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A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.
Rheumatoid arthritis (RA) is a form of arthritis that causes pain, swelling, and stiffness in your joints. RA is an autoimmune disease. Although it is most common in the wrist and fingers, this disease can cause your immune system to attack any joint tissue. The inflammation (swelling) that comes with RA can also affect other body parts. Inflammation could cause medical issues in your eyes, skin, heart, nerves, blood, or lungs.
RA differs from osteoarthritis, a common arthritis that often comes with age. RA affects the lining of your joints and damages the tissue that covers the ends of the bones in a joint. Eventually, this might cause your joints to not work as well.
There is no cure for RA, but early treatment can help you manage symptoms, reduce joint damage, and lead a productive life.
From MedlinePlus: Rheumatoid Arthritis (US National Library of Medicine) ↗
🛡️ Autoimmune diseases: In autoimmune diseases the immune system, which should fight germs, attacks the body's own healthy tissue - the joints in rheumatoid arthritis, many organs in lupus, nerves in multiple sclerosis.
General information about autoimmune diseases, reviewed by people; it does not describe any one person. Below: the evidence for rheumatoid arthritis itself.
AI reads the targets, drugs, trials and papers below and writes where the science stands — every claim cited. It is shared with everyone who opens rheumatoid arthritis.
Green labels: what the target is known to be druggable by. The score combines genetics, somatic mutations, drugs, expression and literature.
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