AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

📰

Breakthrough Tracker

Every week AI Cure reads the newest phase 3 results, the papers in the leading journals and the US drug label updates, and AI explains what changed — every point cited. For 36 cancers, starting with the ones that matter most in India.

Breakthroughs around the world

The world is fighting cancer - right now

Every green pulse is a country recruiting cancer patients into trials today. Beside it, the newest phase 3 results, as they are posted.

109countries recruiting
102phase 3 results this year
83papers in leading journals
Triple-negative breast carcinomaStudy of Pembrolizumab (MK-3475) Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-522/KEYNOTE-522)NCT03036488 · results posted 2026-10-22 · Merck Sharp & Dohme LLC Hodgkins lymphomaBrentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCLNCT04404283 · results posted 2026-10-21 · Seagen, a wholly owned subsidiary of Pf… Hodgkins lymphomaNKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell LymphomaNCT05664217 · results posted 2026-10-16 · Nektar Therapeutics Small cell lung carcinomaA Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive or Rearranged During Transfection (RET)-Positive CancerNCT03194893 · results posted 2026-10-09 · Hoffmann-La Roche Small cell lung carcinomaA Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer (IMpower030)NCT03456063 · results posted 2026-10-09 · Hoffmann-La Roche Small cell lung carcinomaTesting the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung CancerNCT04214262 · results posted 2026-10-06 · National Cancer Institute (NCI) MesotheliomaDuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural MesotheliomaNCT04334759 · results posted 2026-10-01 · PrECOG, LLC. Breast cancerA Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast CancerNCT05132582 · results posted 2026-09-29 · Seagen, a wholly owned subsidiary of Pf… Urinary bladder cancerA Phase 3 Study of UGN-103 for Treatment of Patients With Low-grade Intermediate-risk Non-muscle Invasive Bladder CancerNCT06331299 · results posted 2026-09-28 · UroGen Pharma Ltd. Urinary bladder cancerA Study of Atezolizumab Versus Placebo as Adjuvant Therapy in Participants With High-risk Muscle-invasive Bladder Cancer (MIBC) Who Are ctDNA Positive Following CystectomyNCT04660344 · results posted 2026-09-28 · Hoffmann-La Roche B-cell chronic lymphocytic leukemiaA Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)NCT05023980 · results posted 2026-09-25 · Loxo Oncology, Inc. Ovarian cancerRelacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube CancerNCT05257408 · results posted 2026-09-25 · Corcept Therapeutics Renal cell carcinomaA Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With Previously Treated Clear Cell Renal Cell Carcinoma That is Advanced or Has SpreadNCT04810078 · results posted 2026-09-22 · Bristol-Myers Squibb Small cell lung carcinomaDouble Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLCNCT02273375 · results posted 2026-09-14 · Canadian Cancer Trials Group MelanomaPercutaneous Hepatic Perfusion in Patients With Hepatic-dominant Ocular MelanomaNCT02678572 · results posted 2026-09-10 · Delcath Systems Inc. Prostate cancerCapivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN DeficiencyNCT04493853 · results posted 2026-09-10 · AstraZeneca Hepatocellular carcinomaSafety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)NCT04246177 · results posted 2026-09-03 · Merck Sharp & Dohme LLC Cervical cancerImpact of Applying a Bandage Skin Hydrogel on the Pains of the Head and Neck in Patients With Cancer of Head and Neck Treated With RadiotherapyNCT01520701 · results posted 2026-09-01 · Centre Francois Baclesse B-cell chronic lymphocytic leukemiaAcalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia PatientsNCT04008706 · results posted 2026-09-01 · AstraZeneca MelanomaA Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable MelanomaNCT05625399 · results posted 2026-08-26 · Bristol-Myers Squibb

Sources: ClinicalTrials.gov (recruiting trials and posted results), PubMed (leading journals). Refreshed every week.

Most common in India

🫁 Lung cancer

The leading cause of cancer death worldwide, and a major one in India.

12 phase 3 results12 papers0 label updatesupdated 2026-10-26
🎀 Breast cancer

The most common cancer in women in India and the world.

12 phase 3 results12 papers0 label updatesupdated 2026-10-26
👄 Oral cancer

Among the most common cancers in Indian men, driven by tobacco and areca nut - and often preventable.

7 phase 3 results4 papers0 label updatesupdated 2026-10-26
🌸 Cervical cancer

Caused by HPV, preventable by vaccination and screening, yet still a leading cancer in Indian women.

10 phase 3 results12 papers8 label updatesupdated 2026-10-26
🔬 Pancreatic cancer

One of the deadliest cancers, usually found late, with few good treatments - where new ideas matter most.

4 phase 3 results12 papers4 label updatesupdated 2026-10-26
🗣️ Head and neck cancer

Cancers of the mouth, throat and voice box: very common in India, mostly from tobacco and alcohol.

7 phase 3 results12 papers6 label updatesupdated 2026-10-26
🩺 Colorectal cancer

Bowel cancer: rising in India, especially in younger adults, and curable when found early.

10 phase 3 results12 papers8 label updatesupdated 2026-10-26
🫃 Stomach cancer

Common in north-east India; often linked to H. pylori infection, diet and smoking.

1 phase 3 result12 papers0 label updatesupdated 2026-10-26
🥤 Oesophageal cancer

Cancer of the food pipe: common in north-east India and Kashmir, usually found late.

4 phase 3 results12 papers6 label updatesupdated 2026-10-26
🌺 Ovarian cancer

Often silent until advanced; BRCA changes make some cases strongly treatable.

5 phase 3 results12 papers8 label updatesupdated 2026-10-26
🟢 Gallbladder cancer

Unusually common in northern and north-eastern India, along the Gangetic plain - and little studied.

0 phase 3 results12 papers0 label updatesupdated 2026-10-26
🟤 Liver cancer

Hepatocellular carcinoma: linked to hepatitis B and C, alcohol and fatty liver disease.

5 phase 3 results12 papers0 label updatesupdated 2026-10-26

More cancers

🧬 Prostate cancer

The most common cancer in men in many countries, and rising in Indian cities.

7 phase 3 results12 papers8 label updatesupdated 2026-10-26
🫘 Kidney cancer

Renal cell carcinoma: often found by chance on a scan; targeted drugs and immunotherapy changed its outlook.

2 phase 3 results12 papers0 label updatesupdated 2026-10-26
💧 Bladder cancer

Strongly linked to smoking; blood in the urine is the warning sign.

5 phase 3 results12 papers8 label updatesupdated 2026-10-26
🦋 Thyroid cancer

Usually very treatable; more common in women.

1 phase 3 result12 papers3 label updatesupdated 2026-10-26
🌷 Uterine (endometrial) cancer

Cancer of the womb lining, rising with obesity; bleeding after the menopause is the warning sign.

1 phase 3 result12 papers1 label updateupdated 2026-10-26
🧠 Glioblastoma (brain cancer)

The most aggressive brain cancer, with few treatments - a top priority for new ideas.

1 phase 3 result12 papers8 label updatesupdated 2026-10-26
☀️ Melanoma

Skin cancer where immunotherapy first transformed survival.

4 phase 3 results12 papers8 label updatesupdated 2026-10-26
🟡 Bile duct cancer

Cholangiocarcinoma: rare, hard to treat, with new targeted options for FGFR2 and IDH1 changes.

1 phase 3 result12 papers4 label updatesupdated 2026-10-26
🌬️ Small-cell lung cancer

A fast-growing lung cancer closely tied to smoking, with few targeted options.

12 phase 3 results12 papers8 label updatesupdated 2026-10-26
🎗️ Triple-negative breast cancer

The hardest-to-treat breast cancer, more common in younger women.

4 phase 3 results12 papers4 label updatesupdated 2026-10-26
🏭 Mesothelioma

Caused by asbestos; a rare cancer of the lining of the lungs.

2 phase 3 results8 papers7 label updatesupdated 2026-10-26
👃 Nasopharyngeal cancer

Linked to the Epstein-Barr virus; more common in north-east India.

0 phase 3 results12 papers0 label updatesupdated 2026-10-26

Blood cancers

🩸 Acute myeloid leukaemia

A fast blood cancer of adults, with many new targeted drugs (FLT3, IDH, menin).

2 phase 3 results12 papers8 label updatesupdated 2026-10-26
🧒 Acute lymphoblastic leukaemia

The most common childhood cancer - most children are now cured.

0 phase 3 results12 papers8 label updatesupdated 2026-10-26
🩸 Chronic lymphocytic leukaemia

A slow blood cancer of older adults, transformed by BTK and BCL2 inhibitors.

3 phase 3 results12 papers8 label updatesupdated 2026-10-26
🩸 Chronic myeloid leukaemia

The first cancer tamed by a targeted pill (imatinib).

2 phase 3 results12 papers6 label updatesupdated 2026-10-26
🧫 Diffuse large B-cell lymphoma

The most common aggressive lymphoma; CAR-T and bispecific antibodies are new options.

3 phase 3 results12 papers8 label updatesupdated 2026-10-26
🧫 Hodgkin lymphoma

A lymphoma of young adults that is usually curable.

6 phase 3 results12 papers8 label updatesupdated 2026-10-26
🦴 Multiple myeloma

A cancer of plasma cells in the bone marrow; many new drugs, but still rarely cured.

6 phase 3 results12 papers8 label updatesupdated 2026-10-26

Children, young people and rare cancers

👶 Neuroblastoma

A cancer of young children that grows from nerve cells.

0 phase 3 results12 papers7 label updatesupdated 2026-10-26
🦴 Osteosarcoma

Bone cancer of teenagers and young adults, with little progress in decades.

0 phase 3 results5 papers6 label updatesupdated 2026-10-26
💪 Soft tissue sarcoma

Rare cancers of muscle, fat and connective tissue - more than 50 kinds.

1 phase 3 result12 papers4 label updatesupdated 2026-10-26
⚽ Testicular cancer

The most common cancer in young men, and usually curable.

0 phase 3 results12 papers4 label updatesupdated 2026-10-26
👁️ Uveal melanoma (eye)

A rare eye cancer, unlike skin melanoma, that often spreads to the liver.

1 phase 3 result12 papers2 label updatesupdated 2026-10-26

Any other disease has a Breakthrough Tracker too: open it in the Disease Atlas and choose “Breakthroughs”.

🗺️ Find a disease
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy