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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for ALK+ Non-Small-Cell Lung Carcinoma

A Real World Study of Ensartinib in Advanced ALK-positive NSCLC NCT05498064n/a1 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: Ensartinib Neoadjuvant WX-0593 in Resectable ALK-positive or ROS1-positive Non-small Cell Lung Cancer NCT05765877Phase 21 site๐Ÿ“ Jinan Pingping Song ยท Tests: WX-0593 Tablets Adjuvant Therapy of Ensartinib in Stage IB-IIIA ALK-positive Non-small Cell Lung Cancer NCT05241028Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: Ensartinib Lorlatinib Plus Local Consolidation Therapy In ALK Positive Advanced Non-Small Cell Lung Cancer NCT07415005Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Lorlatinib A Study to Evaluate the Combination of Platinum-pemetrexed Based Chemotherapy Plus Lorlatinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) With Exclusively Extracranial Disease Progression on Lorlatinib NCT06378892Phase 29 sites๐Ÿ“ Aviano๐Ÿ“ Florence๐Ÿ“ Lido di Camaiore Centro di Riferimento Oncologico - Aviano ยท Tests: Lorlatinib Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy NCT03042221n/a1 site๐Ÿ“ Aurora University of Colorado, Denver Trial for Local Ablative Treatment (LAT) Optimization in Patients With Advanced Non-Small Cells Lung Cancer (NSCLC) Presenting an Anaplastic Lymphoma Kinase (ALK) Rearrangement Treated by Brigatinib NCT06620835Phase 227 sites๐Ÿ“ Brest๐Ÿ“ Caen๐Ÿ“ Chambรฉry Groupe Francais De Pneumo-Cancerologie ยท Tests: Blood samples for Hematology, Blood samples for Chemistry, Blood sample for liver function tests, Pregnancy test, Tumouโ€ฆ AQUA07 in Patients With ALK-Positive Non-Small Cell Lung Cancer NCT07617337Phase 17 sites๐Ÿ“ Houston๐Ÿ“ Nagoya๐Ÿ“ Kashiwa Chugai Pharmaceutical ยท Tests: AQUA07, Lorlatinib ALK Tyrosine Kinase Inhibitors in ALK-rearranged Advanced Squamous Cell Carcinoma NCT05014464Phase 21 site๐Ÿ“ Changsha Hunan Province Tumor Hospital ยท Tests: Crizotinib Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC NCT05681780Phase 11 site๐Ÿ“ Tampa H. Lee Moffitt Cancer Center and Research Institute ยท Tests: Tumor-infiltrating Lymphocytes (TIL), Nivolumab, Cyclophosphamide, Fludarabine, Tumor-infiltrating Lymphocyte Therapy Efficacy and Safety of Ivonescimab Monotherapy as First-Line Treatment for PD-L1-Positive, Driver Gene-Negative, Locally Advanced or Metastatic NSCLC: A Multicenter, Prospective, Real-World Cohort Study NCT07696832n/a1 site๐Ÿ“ Guangzhou Guangdong Association of Clinical Trials ยท Tests: Ivonescimab Injection Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation NCT04322890Phase 21 site๐Ÿ“ Changsha Hunan Province Tumor Hospital ยท Tests: Osimertinib, Alectinib 150 MG, Crizotinib 250 MG, Savolitinib, Crizotinib., Chemotherapy Analysis of the Effectiveness and Safety of Lorlatinib in Untreated ALK-Positive NSCLC Patients in a French Real-World Context NCT06487078NA32 sites๐Ÿ“ Toulouse๐Ÿ“ Paris๐Ÿ“ Aix-en-Provence Pfizer ยท Tests: Lorlatinib Analysis of Biological Characteristics of Advanced ALK-rearranged NSCLC NCT05122806NA46 sites๐Ÿ“ Saint-Denis๐Ÿ“ Aix-en-Provence๐Ÿ“ Amiens Groupe Francais De Pneumo-Cancerologie ยท Tests: RNAseq Alectinib Pharmacokinetic in Patients With NSCLC NCT05713006Phase 1, Phase 21 site๐Ÿ“ Mexico City Instituto Nacional de Cancerologia de Mexico ยท Tests: Alectinib Oral Product Peptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLC NCT05950139Phase 1, Phase 21 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Peptide vaccine A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC NCT06627647Phase 3300 sites๐Ÿ“ Mobile๐Ÿ“ Chandler๐Ÿ“ Phoenix AstraZeneca ยท Tests: Rilvegostomig, Pembrolizumab, Carboplatin, Cisplatin, Pemetrexed Comparison of Standard Dose Alectinib to Alectinib in Adjusted Dose Based on Alectinib Bloodlevels NCT05525338Phase 48 sites๐Ÿ“ Villejuif๐Ÿ“ Nijmegen๐Ÿ“ Maastricht University Medical Center Groningen ยท Tests: Alectinib A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC) NCT07140016Phase 117 sites๐Ÿ“ Fullerton๐Ÿ“ Orange๐Ÿ“ Edwards Astellas Pharma Global Development, Inc. ยท Tests: gilteritinib Real World Clinical Outcomes of Resected ALK-Positive Early Stage NSCLC Patients Treated With Alectinib as Adjuvant Therapy NCT06862869n/a44 sites๐Ÿ“ Zhanjiang๐Ÿ“ Guangzhou๐Ÿ“ Kaifeng Hoffmann-La Roche ยท Tests: Alectinib Immunotherapy Without Chemotherapy for Advanced Lung Cancer Patients With High PD-L1 Levels NCT07360743Phase 24 sites๐Ÿ“ Bordeaux๐Ÿ“ Boulogne-Billancourt๐Ÿ“ Nice UNICANCER ยท Tests: Pembrolizumab, Cemiplimab Patient-centered, Optimal Integration of Survivorship and Palliative Care NCT04900935NA1 site๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: POISE A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma NCT05456256Phase 216 sites๐Ÿ“ Beverly Hills๐Ÿ“ Fountain Valley๐Ÿ“ Los Alamitos Lantern Pharma Inc. ยท Tests: LP-300, Pemetrexed, Carboplatin Savolitinib Plus Docetaxel as 2L in EGFR/ALK/ROS1/MET ex14m-wildtype NSCLC With MET Overexpression NCT05777278Phase 1, Phase 21 site๐Ÿ“ Guangzhou The First Affiliated Hospital of Guangzhou Medical Universiโ€ฆ ยท Tests: Savolitinib, Docetaxel Efficacy of Platinum-based Chemotherapy Plus Immune Checkpoint Inhibitors for EGFR/ALK/ROS1 Mutant Lung Cancer NCT05284539Phase 21 site๐Ÿ“ Changsha Hunan Province Tumor Hospital ยท Tests: Pemetrexed, Cisplatin, Bevacizumab Plus Pembrolizumab Lorlatinib as the First-line Treatment in China Advanced ALK+ NSCLC NCT06092086Phase 21 site๐Ÿ“ Guangzhou Guangdong Association of Clinical Trials ยท Tests: Loratinib A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites๐Ÿ“ Aurora๐Ÿ“ Lake Mary๐Ÿ“ Lebanon 7 Hills Pharma, LLC ยท Tests: Alintegimod, Ipilimumab, Nivolumab Alectinib Followed by Concomitant Consolidation Radiation Therapy in Advanced NSCLC With ALK-rearrangement (A-SAB) NCT05724004NA1 site๐Ÿ“ Stockholm Karolinska University Hospital ยท Tests: SBRT/SRS/radiation therapy Gilteritinib for the Treatment of ALK NSCLC NCT06225427Phase 13 sites๐Ÿ“ Los Angeles๐Ÿ“ Washington D.C.๐Ÿ“ Ann Arbor University of Michigan Rogel Cancer Center ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Echocardiography, Gilteritinib Real World Study of Lolatinib for Advanced ALK+ NSCLC Patients NCT06361589n/a1 site๐Ÿ“ Chengdu Sichuan Cancer Hospital and Research Institute ยท Tests: Lorlatinib
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