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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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19 recruiting trials

for Accelerated Phase Myeloproliferative Neoplasm

Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia NCT03263572Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Blinatumomab, Cytarabine, Methotrexate, Ponatinib Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors NCT03934372Phase 1, Phase 223 sites๐Ÿ“ Ghent๐Ÿ“ Paris๐Ÿ“ Paris Incyte Biosciences International Sร rl ยท Tests: Ponatinib Pacritinib With Standard of Care Azacitidine or Decitabine as a Bridge to Allogeneic Hematopoietic Stem Cell Transplant for Patients With Accelerated and Blast Phase Myeloproliferative Neoplasms NCT07148947Phase 21 site๐Ÿ“ Seattle University of Washington ยท Tests: Pacritinib, Decitabine, Decitabine and Cedazuridine, Azacitidine, Survey Administration A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs) NCT06661915Phase 231 sites๐Ÿ“ Irvine๐Ÿ“ Orange๐Ÿ“ Palo Alto National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Decitabine and Cedazuridine, Iadademstat TGRX-678 Chinese Phase II in Chronic Myelogenous Leukemia (CML) Patients NCT06453902Phase 21 site๐Ÿ“ Beijing Shenzhen TargetRx Co., Ltd. ยท Tests: TGRX-678 Personalized NK Cell Therapy in CBT NCT02727803Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Allogeneic Natural Killer Cell Line NK-92, Anti-Thymocyte Globulin, Busulfan, Clofarabine, Cyclophosphamide MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing NCT05794880NA1 site๐Ÿ“ Milwaukee Medical College of Wisconsin ยท Tests: Magnetic-Activated Cell Sorter (CliniMACS, Miltenyi) Open-label Study of Asciminib for CML-CP or CML-AP Patients With T315I Mutation Who Are Resistant, Intolerant or Ineligible to Ponatinib. NCT06514534Phase 26 sites๐Ÿ“ Bordeaux๐Ÿ“ Lille๐Ÿ“ Lyon Novartis Pharmaceuticals ยท Tests: ABL001/Asciminib Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms NCT04282187Phase 21 site๐Ÿ“ Seattle University of Washington ยท Tests: Decitabine, Ruxolitinib, Fedratinib, Questionnaire Administration, Pacritinib Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS) NCT06802315Phase 21 site๐Ÿ“ Chicago University of Illinois at Chicago ยท Tests: Intensity modulated total marrow irradiation, Cyclophosphamide (CTX), Fludarabine (Fludara), Busulfan (conditioning forโ€ฆ Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms NCT05074355Phase 21 site๐Ÿ“ Toronto University Health Network, Toronto ยท Tests: Azacitidine, Venetoclax Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) NCT05322850Phase 1, Phase 24 sites๐Ÿ“ Gainesville๐Ÿ“ Miami๐Ÿ“ Miami University of Florida ยท Tests: Orca-Q MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs) NCT07362225n/a2 sites๐Ÿ“ Chicago๐Ÿ“ New York MPN Research Foundation A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant NCT07020533Phase 13 sites๐Ÿ“ Duarte๐Ÿ“ Atlanta๐Ÿ“ Boston City of Hope Medical Center ยท Tests: Biospecimen Collection, Electronic Health Record Review, Haploidentical Hematopoietic Cell Transplantation, Letermovir,โ€ฆ Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL NCT04260022Phase 19 sites๐Ÿ“ Birmingham๐Ÿ“ Duarte๐Ÿ“ Atlanta Ascentage Pharma Group Inc. ยท Tests: Ascentage Pharma HQP1351 bioavailable inhibitor, Blinatumomab (Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis NCT04996875Phase 242 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ Duarte Cogent Biosciences, Inc. ยท Tests: bezuclastinib Asciminib Roll-over Study NCT04877522Phase 485 sites๐Ÿ“ Ann Arbor๐Ÿ“ New York๐Ÿ“ Portland Novartis Pharmaceuticals ยท Tests: Asciminib single agent, Imatinib, Nilotinib, Bosutinib, Dasatinib Registry of Older Patients With Cancer NCT01137825n/a7 sites๐Ÿ“ Boone๐Ÿ“ Chapel Hill๐Ÿ“ Greenville UNC Lineberger Comprehensive Cancer Center Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer NCT01137643n/a1 site๐Ÿ“ Chapel Hill UNC Lineberger Comprehensive Cancer Center ยท Tests: biologic sample preservation procedure, cytology specimen collection procedure
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