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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Acute Leukemia, High Risk

Demethylating Agents Combined With Venetoclax for High-risk T-cell Lymphoblastic Lymphoma/Leukemia Post-Transplant Relapse Prevention NCT06686108Phase 21 site๐Ÿ“ Shanghai Shanghai General Hospital, Shanghai Jiao Tong University Scโ€ฆ ยท Tests: Azacitidine (AZA) Days 1 - 5, Decitabine (DAC), Venetoclax Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse NCT06928662Phase 1, Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Decitabine, Bone Marrow Aspiration, Bone Marrow Biopsy, Chest Radiography, Cytarabine Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome NCT00801489Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cytarabine, Decitabine, Filgrastim-sndz, Fludarabine Phosphate, Gemtuzumab Ozogamicin HVA vs IA/DA or VA in the Treatment of ND HR-AML NCT06810791Phase 31 site๐Ÿ“ Guangzhou Nanfang Hospital, Southern Medical University ยท Tests: HVA, VA, Standard Chemotherapy Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia NCT03136146Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Bortezomib, Clofarabine, Cyclophosphamide, Dexamethasone, Etoposide Venetoclax and Azacitidine Combined With Homoharringtonine, Followed by Allo-HSCT for Intermediate and High-risk AML. NCT06483906Phase 21 site๐Ÿ“ Shanghai Shanghai General Hospital, Shanghai Jiao Tong University Scโ€ฆ ยท Tests: Venetoclax, Azacitidine and Homoharringtonine A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS. NCT04275518Phase 114 sites๐Ÿ“ Beijing๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Ascentage Pharma Group Inc. ยท Tests: APG-115, Azacitidine, Cytarabine Orphan Indications for CD19 Redirected Autologous T Cells NCT04276870Phase 21 site๐Ÿ“ Philadelphia Stephan Grupp MD PhD ยท Tests: Murine CART19 Blinatumomab After TCR Alpha Beta/CD19 Depleted HCT NCT04746209Phase 21 site๐Ÿ“ Milwaukee Medical College of Wisconsin ยท Tests: Alpha/Beta T-cell and B-cell depleted HCT, Blinatumomab Venetoclax Basket Trial for High Risk Hematologic Malignancies NCT05292664Phase 15 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Atlanta Andrew E. Place, MD ยท Tests: Venetoclax, Azacitidine, Cytarabine, Methotrexate, Hydrocortisone Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS NCT04708054Phase 2, Phase 31 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Busulfan, Cladribine, Fludarabine Phosphate, Hematopoietic Cell Transplantation, Thiotepa Individualized AML Treatment NCT07613385n/a1 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Observational Novel Digital Application for Patients With Acute Leukemia NCT06472128NA3 sites๐Ÿ“ Boston๐Ÿ“ Durham๐Ÿ“ Seattle Massachusetts General Hospital ยท Tests: DREAMLAND, VITAL WELLNESS Treatment of CD19 Chimeric Antigen Receptor T Cells for Pediatric Patients With CD19-positive B-cell Acute Lymphoblastic Leukemia Who Are Indicated for Hematopoietic Stem Cell Transplantation NCT06247501Phase 21 site๐Ÿ“ Seoul Seoul National University Hospital ยท Tests: SNUH-CD19-CAR-T MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies NCT05735717Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome NCT07582172Phase 21 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Echocardiography Test, Fludarabine Phosphate Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol NCT06764238Phase 2, Phase 327 sites๐Ÿ“ Hefei๐Ÿ“ Hefei๐Ÿ“ Fuzhou Institute of Hematology & Blood Diseases Hospital, China ยท Tests: Blinatumomab (Group A), Venetoclax (nonRand Group), Blinatumomab (Group B) HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML NCT06594445Phase 11 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: GTB-360 Novel Unedited Allo Cell Therapy For High Risk T-Cell Malignancies Using CD7-Specific Car T Cells NCT07220993Phase 12 sites๐Ÿ“ Houston๐Ÿ“ Houston Baylor College of Medicine ยท Tests: CD7.CAR/28zeta T Cells Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR NCT02416388Phase 2, Phase 356 sites๐Ÿ“ Amiens๐Ÿ“ Angers๐Ÿ“ Argenteuil University Hospital, Angers ยท Tests: Idarubicin, Daunorubicin, HD Cytarabine, Cyclosporine, Methotrexate Monitoring Minimal Residual Disease of Patients With Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome NCT01311258n/a1 site๐Ÿ“ Rochester University of Rochester Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy NCT03630991Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Edetate Calcium Disodium, Multivitamin, Succimer SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) NCT03113643Phase 13 sites๐Ÿ“ Duarte๐Ÿ“ Boston๐Ÿ“ Houston Dana-Farber Cancer Institute ยท Tests: Azacitidine, SL-401, Venetoclax 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome NCT06287944Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Actinium Ac 225-DOTA-Daratumumab, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomograpโ€ฆ A Study Testing an Improved Dose of UM171 to Help Make Cord Blood Transplants More Effective and Safe. NCT07301866Phase 1, Phase 21 site๐Ÿ“ Montreal Ciusss de L'Est de l'รŽle de Montrรฉal ยท Tests: ECT-001-CB Thiotepa Combined With Busulfan and Fludarabine Conditioning Regimen for Haploidentical Hematopoietic Stem Cell Transplantation in Elderly Patients With High-Risk Acute Myeloid Leukemia NCT06869265Phase 21 site๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: Thiotepa ;busulfan;fludarabine First-in-human (FIH) Trial of GEN3018 in Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML) or Higher-risk Myelodysplastic Syndrome (HR-MDS) NCT07384715Phase 16 sites๐Ÿ“ Aarhus๐Ÿ“ Copenhagen๐Ÿ“ Barcelona Genmab ยท Tests: GEN3018 Trial of Novel Anti-leukemia Agents in Flu/Mel RIC Transplant for Myeloid Malignancies NCT07044544Phase 11 site๐Ÿ“ Birmingham University of Alabama at Birmingham ยท Tests: G-CSF, Decitabine, Venetoclax Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders NCT04644016Phase 21 site๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: Clofarabine, Fludarabine, Busulfan, Cyclosporine-A, Mycophenolate Mofetil Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome NCT03661307Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Decitabine, Quizartinib, Venetoclax
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