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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Acute Lymphoblastic Leukemia, Adult

Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL NCT06481228NA1 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: CAR-T cells, Venetoclax, Olverembatinib A Multicenter Study of CAR-T Cells in Primary Ph+All NCT07252336Phase 21 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: CD19 CAR-T cells VHAG in Treating R/R T-ALL/LBL NCT06742463Phase 21 site๐Ÿ“ Hangzhou First Affiliated Hospital of Zhejiang University ยท Tests: Venetoclax, homoharringtonine, Cytarabine (Ara-C), G-CSF Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia NCT03136146Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Bortezomib, Clofarabine, Cyclophosphamide, Dexamethasone, Etoposide CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia NCT07328503Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: CD22 CAR-transduced T cells, Cyclophosphamide, Fludarabine A Study of Obecabtagene Autoleucel in People With B-cell Acute Lymphoblastic Leukemia NCT07400029Phase 29 sites๐Ÿ“ Duarte๐Ÿ“ Stanford๐Ÿ“ Basking Ridge Memorial Sloan Kettering Cancer Center ยท Tests: Obecabtagene Autoleucel Asciminib as Maintenance Treatment After Cellular Therapies for Adults With Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia NCT07040982Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Asciminib, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Echocardiography Test Cord Blood Transplantation in Children and Young Adults With Blood Cancer NCT07566377Phase 21 site๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: Cord Blood Units, Total Body Irradiation, Cyclophosphamide, Fludarabine, Clofarabine CD19 Chimeric Antigen Receptor (CAR) T Cells in Adults With Relapsed/Refractory CD19 Positive Acute Lymphoblastic Leukemia NCT07361029Phase 11 site๐Ÿ“ Riyadh King Faisal Specialist Hospital & Research Center ยท Tests: CAR T cells chimeric antigen receptor cells Ma-Spore ALL 2020 Study NCT06336395Phase 23 sites๐Ÿ“ Kuala Lumpur๐Ÿ“ Kuala Lumpur๐Ÿ“ Singapore National University Hospital, Singapore ยท Tests: Prednisolone, Dexamethasone, Vincristine, Methotrexate, L-Asparaginase Safety Study of CC312 in Adult Patients With Relapsed/Refractory CD19 Positive B-cell Hematologic Malignancies NCT06037018Phase 11 site๐Ÿ“ Tianjin CytoCares Inc ยท Tests: CC312 Orphan Indications for CD19 Redirected Autologous T Cells NCT04276870Phase 21 site๐Ÿ“ Philadelphia Stephan Grupp MD PhD ยท Tests: Murine CART19 Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies NCT07648264Phase 360 sites๐Ÿ“ Orange๐Ÿ“ Denver๐Ÿ“ Coral Springs CSL Behring ยท Tests: IgPro20 "Triple Negative" Adult B-cell Acute Lymphoblastic Leukemia - TRINEG-ALL NCT06919393n/a3 sites๐Ÿ“ Meldola๐Ÿ“ Ravenna๐Ÿ“ Rimini Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRโ€ฆ ยท Tests: "Triple negative" adul B-cell ALL Pediatric-Inspired Regimen Combined With Venetoclax and Immunotherapy for Adult Ph-Negative Acute Lymphoblastic Leukemia NCT07495631NA1 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: VDCLP+V, 2VIP, Consolidation Therapy, Maintenance Therapy, Blinatumomab Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil NCT05959720n/a1 site๐Ÿ“ Sรฃo Paulo Instituto do Cancer do Estado de Sรฃo Paulo ยท Tests: Prednisone, Vincristin, Daunorubicin, Peg-asparaginase, Intrathecal Suspension Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome NCT06128070Phase 21 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biospecimen Collection, Chest Computed Tomography, Echocardiography, Hematopoietic Cell Transplantation, Methotrexate Venetoclax Basket Trial for High Risk Hematologic Malignancies NCT05292664Phase 15 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Atlanta Andrew E. Place, MD ยท Tests: Venetoclax, Azacitidine, Cytarabine, Methotrexate, Hydrocortisone Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia NCT06446661NA1 site๐Ÿ“ Chicago University of Chicago ยท Tests: High Intensity, No Text Messagings, Low Intensity Text Messaging Recombinant Erwinia Asparaginase and Venetoclax in Combination With Blinatumomab for the Treatment of Relapsed or Refractory CD19 Positive B-cell Acute Lymphoblastic Leukemia NCT07133997Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Blinatumomab, Bone Marrow Aspiration, Bone Marrow Biopsy MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies NCT05735717Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma NCT07356245Phase 21 site๐Ÿ“ Columbus Jonathan Brammer ยท Tests: Ruxolitinib, Positron emission tomography-computed tomography, Bone Marrow Biopsy, Biopsy Procedure, Biospecimen Collecโ€ฆ Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with Hemoblastosis NCT06756152Phase 2, Phase 31 site๐Ÿ“ Moscow Federal Research Institute of Pediatric Hematology, Oncologโ€ฆ ยท Tests: Conditioning regimen: Treosulfan 42 g/m2/course or total body irradiation 12 Gray/course, Etoposide 60 mg/kg , Fludarabโ€ฆ ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL NCT07454226NA1 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: Olverembatinib, Gecacitinib, Venetoclax, Chemotherapy Regimen, Blinatumomab Anti-CD19, Dual Co-stimulatory (4-1BB, CD3ฮถ) Chimeric Antigen Receptor T-cells in Patients With Relapsed/Refractory Aggressive Lymphoma or Acute Lymphoblastic Leukemia (ALL) NCT03938987Phase 1, Phase 26 sites๐Ÿ“ Calgary๐Ÿ“ Calgary๐Ÿ“ Calgary University of Alberta ยท Tests: autologous CD19-directed chimeric antigen receptor (CAR) T-cells Determining the Mechanisms of Loss of CAR T Cell Persistence NCT05809284n/a3 sites๐Ÿ“ London๐Ÿ“ London๐Ÿ“ Manchester University College, London Clinical Study of LV009 Injection for the Treatment of Relapsed/Refractory CD19-Positive Hematologic and Lymphoid Malignancies NCT07312630EARLY Phase 11 site๐Ÿ“ Hefei PersonGen BioTherapeutics (Suzhou) Co., Ltd. ยท Tests: LV009 Injection Infusion A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) NCT01351545n/a142 sites๐Ÿ“ Birmingham๐Ÿ“ Gilbert๐Ÿ“ Phoenix Center for International Blood and Marrow Transplant Researโ€ฆ ยท Tests: A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant NCT03326921Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: CD8+ and CD4+ Donor Memory T-cells-expressing HA1-Specific TCR, Bone Marrow Aspiration, Biospecimen Collection CalPeg for Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) NCT05581030Phase 11 site๐Ÿ“ Tampa H. Lee Moffitt Cancer Center and Research Institute ยท Tests: Hyper CVAD Protocol (Standard of Care Multi-Agent Chemotherapy), Calaspargase Pegol, Rituximab
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