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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Adenocarcinoma - GEJ

Perioperative Chemotherapy Combined With Serplulimab or Placebo for pMMR Locally Advanced Gastric Adenocarcinoma (FOCUS-05) NCT05872685Phase 25 sites📍 Hangzhou📍 Hangzhou📍 Lishui Yu jiren · Tests: S1, Oxaliplatin, Serplulimab, Placebo A Multicenter Randomized Controlled Phase II Trial of Iparomlimab and Tuvonralimab (QL1706) Combined With SOX Chemotherapy Versus Chemotherapy Alone in the Treatment of Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma NCT06829797Phase 21 site📍 Jinan Shandong Provincial Hospital · Tests: Neoadjuvant Therapy(QL1706+SOX Chemotherapy), Neoadjuvant Therapy(SOX Chemotherapy), Radical surgery (D2), Drug: Adjuva… CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site📍 Chicago Northwestern University · Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride Registry Platform Gastric/Esophageal Cancer (SAPHIR) NCT04290806n/a1 site📍 Multiple Locations iOMEDICO AG · Tests: Routine care as per site standard First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2) NCT06730373Phase 220 sites📍 Zhengzhou📍 Binzhou📍 Dongying Qilu Hospital of Shandong University · Tests: Disitamab Vedotin, Sintilimab, S-1, Trastuzumab, Oxaliplatin Ph1b/2 Study of the Safety and Efficacy of SHR-A1811 Combinations in Advanced HER2 Expression Gastric Cancer NCT05671822Phase 21 site📍 Shanghai Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Tests: SHR-A1811 and SHR-1701, SHR-A1811 and capecitabine, SHR-A181, SHR-1701, and capecitabine, SHR-A1811, SHR-1316, and cape… A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer NCT05365581Phase 146 sites📍 Orange📍 Santa Monica📍 Chicago Astellas Pharma Global Development, Inc. · Tests: ASP2138, Pembrolizumab, Oxaliplatin, Leucovorin, Fluorouracil KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy NCT05427383Phase 2, Phase 31 site📍 Beijing Shanghai JMT-Bio Inc. · Tests: KN026/Placbo Injection, Paclitaxel Injection, Docetaxel Injection, Irinotecan Injection A Study of Cadonilimab Combined With Chemotherapy in People With Gastric or Gastroesophageal Junction Cancer NCT07631000Phase 27 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Cadonilimab Neoadjuvant and Adjuvant Therapy Studies of Sintilimab Combined With Chemotherapy With or Without Ipilimumab N01 in Resectable Gastric/Gastroesophageal Junction Adenocarcinoma NCT07643623Phase 2, Phase 31 site📍 Guangzhou Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. · Tests: tegafur, Gimeracil and Oteracil Potassium Capsules, Sintilimab Placebo, Sintilimab, Ipilimumab N01, Oxaliplatin for inj… Right Versus Left Thoracic Surgical Approaches for Siewert II Gastroesophageal Junction Adenocarcinoma NCT06644352NA1 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: different thoracic surgical approaches IBI343 in Combination Therapy for Advanced Malignant Solid Tumors NCT07483554Phase 21 site📍 Hangzhou Innovent Biologics (Suzhou) Co. Ltd. · Tests: IBI343,Gemcitabine, Albumin-bound Paclitaxel Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Avapritinib Apatinib as the First-Line Therapy in Elderly Locally Advanced or Metastatic Gastric Cancer NCT03219593Phase 21 site📍 Bengbu The First Affiliated Hospital of Bengbu Medical University · Tests: Apatinib mesylate tablets Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study) NCT05482893Phase 1, Phase 211 sites📍 Duarte📍 Los Angeles📍 Denver Phanes Therapeutics · Tests: Spevatamig (PT886), Paclitaxel, Gemcitabine, Abraxane, KEYTRUDA® (pembrolizumab) BC001 in Combination with Sintilimab and XELOX in the Treatment of HER-2 Negative Advanced or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma. NCT06773312Phase 11 site📍 Beijing Sichuan Luzhou Buchang Biopharmaceutical Co., Ltd. · Tests: BC001+Sintilimab+XELOX Combination of Chemotherapy and Adaptive MR-Guided Radiotherapy to Improve Outcomes in Patients With Esophageal Adenocarcinoma NCT07359443Phase 11 site📍 Utrecht UMC Utrecht · Tests: MRI guided radiotherapy A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors NCT06131840Phase 148 sites📍 Phoenix📍 Scottsdale📍 Duarte Seagen, a wholly owned subsidiary of Pfizer · Tests: PF-08046050, bevacizumab, 5-Fluorouracil (5-FU), Oxaliplatin, Leucovorin (LV) Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2) NCT07432295Phase 26 sites📍 Goodyear📍 Duarte📍 Boston I-Mab Biopharma US Limited · Tests: Givastomig, Nivolumab, 5Fluorouracil, Leucovorin, Oxaliplatin Sintilimab Combined With Chemotherapy as Adjuvant Treatment for Phase III GC and GEJ NCT06761846Phase 21 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Sintilimab plus Chemotherapy A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors NCT04895709Phase 1, Phase 247 sites📍 Clovis📍 Los Angeles📍 Newport Beach Bristol-Myers Squibb · Tests: BMS-986340, BMS-936558-01, Docetaxel, Pumitamig Phase 2 Trial of KN026+KN046±XELOX in HER2-positive Locally Advanced GC NCT06023758Phase 21 site📍 Beijing Peking University · Tests: KN026, KN046, XELOX A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer NCT06764875Phase 3304 sites📍 Anchorage📍 Phoenix📍 Duarte AstraZeneca · Tests: Rilvegostomig, Trastuzumab deruxtecan, Trastuzumab, Pembrolizumab, 5-fluorouracil Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer NCT04511039Phase 11 site📍 Buffalo Roswell Park Cancer Institute · Tests: Trifluridine and Tipiracil Hydrochloride, Talazoparib Tosylate Neoadjuvant Tislelizumab + LM-302 + S-1 or Tislelizumab + SOX for CLDN18.2-Positive Gastric/GEJ Adenocarcinoma NCT07569068Phase 21 site📍 Shanghai Ruijin Hospital · Tests: Tislelizumab, LM-302 and S-1, Tislelizumab combined with oxaliplatin and S-1 A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer NCT06123338Phase 210 sites📍 Boston📍 Basking Ridge📍 Middletown Memorial Sloan Kettering Cancer Center · Tests: Pembrolizumab, Trastuzumab, Oxaliplatin, Capecitabine, 5-Fluorouracil DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 16 sites📍 Denver📍 Grand Rapids📍 East Brunswick Duboce Biopharmaceuticals, Inc. · Tests: DBC-664 A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites📍 Birmingham📍 Los Angeles📍 Miami Astellas Pharma Global Development, Inc. · Tests: ASP546C A Study of AK104/Placebo Plus AK109/Placebo And Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma NCT06341335Phase 31 site📍 Beijing Akeso · Tests: cadonilimab, pulocimab, paclitaxel, placebo Capeox Regimen Combined With Sintilimab and Bevacizumab for Gastric Cancer NCT05640609Phase 1, Phase 21 site📍 Chengdu West China Hospital · Tests: Capeox regimen combined with Sintilimab and Bevacizumab
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