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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Gastroesophageal Adenocarcinoma

A Multicenter Randomized Controlled Phase II Trial of Iparomlimab and Tuvonralimab (QL1706) Combined With SOX Chemotherapy Versus Chemotherapy Alone in the Treatment of Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma NCT06829797Phase 21 site📍 Jinan Shandong Provincial Hospital · Tests: Neoadjuvant Therapy(QL1706+SOX Chemotherapy), Neoadjuvant Therapy(SOX Chemotherapy), Radical surgery (D2), Drug: Adjuva… CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site📍 Chicago Northwestern University · Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2) NCT06730373Phase 220 sites📍 Zhengzhou📍 Binzhou📍 Dongying Qilu Hospital of Shandong University · Tests: Disitamab Vedotin, Sintilimab, S-1, Trastuzumab, Oxaliplatin Ph1b/2 Study of the Safety and Efficacy of SHR-A1811 Combinations in Advanced HER2 Expression Gastric Cancer NCT05671822Phase 21 site📍 Shanghai Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Tests: SHR-A1811 and SHR-1701, SHR-A1811 and capecitabine, SHR-A181, SHR-1701, and capecitabine, SHR-A1811, SHR-1316, and cape… A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer NCT05365581Phase 146 sites📍 Orange📍 Santa Monica📍 Chicago Astellas Pharma Global Development, Inc. · Tests: ASP2138, Pembrolizumab, Oxaliplatin, Leucovorin, Fluorouracil KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy NCT05427383Phase 2, Phase 31 site📍 Beijing Shanghai JMT-Bio Inc. · Tests: KN026/Placbo Injection, Paclitaxel Injection, Docetaxel Injection, Irinotecan Injection A Study of Cadonilimab Combined With Chemotherapy in People With Gastric or Gastroesophageal Junction Cancer NCT07631000Phase 27 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Cadonilimab Right Versus Left Thoracic Surgical Approaches for Siewert II Gastroesophageal Junction Adenocarcinoma NCT06644352NA1 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: different thoracic surgical approaches A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors NCT07749586Phase 1, Phase 24 sites📍 New York📍 Huntersville📍 San Antonio Arvinas Inc. · Tests: ARV-6723, Pembrolizumab, SOC IBI343 in Combination Therapy for Advanced Malignant Solid Tumors NCT07483554Phase 21 site📍 Hangzhou Innovent Biologics (Suzhou) Co. Ltd. · Tests: IBI343,Gemcitabine, Albumin-bound Paclitaxel Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Avapritinib Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA NCT07070466Phase 22 sites📍 Santa Monica📍 Boston Massachusetts General Hospital · Tests: Ivonescimab, 5-Fluorouracil, Oxaliplatin, Leucovorin A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors NCT07277413Phase 123 sites📍 Goodyear📍 Phoenix📍 Duarte IDEAYA Biosciences · Tests: IDE892, IDE397 Apatinib as the First-Line Therapy in Elderly Locally Advanced or Metastatic Gastric Cancer NCT03219593Phase 21 site📍 Bengbu The First Affiliated Hospital of Bengbu Medical University · Tests: Apatinib mesylate tablets Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study) NCT05482893Phase 1, Phase 211 sites📍 Duarte📍 Los Angeles📍 Denver Phanes Therapeutics · Tests: Spevatamig (PT886), Paclitaxel, Gemcitabine, Abraxane, KEYTRUDA® (pembrolizumab) BC001 in Combination with Sintilimab and XELOX in the Treatment of HER-2 Negative Advanced or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma. NCT06773312Phase 11 site📍 Beijing Sichuan Luzhou Buchang Biopharmaceutical Co., Ltd. · Tests: BC001+Sintilimab+XELOX A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors NCT06131840Phase 148 sites📍 Phoenix📍 Scottsdale📍 Duarte Seagen, a wholly owned subsidiary of Pfizer · Tests: PF-08046050, bevacizumab, 5-Fluorouracil (5-FU), Oxaliplatin, Leucovorin (LV) Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2) NCT07432295Phase 26 sites📍 Goodyear📍 Duarte📍 Boston I-Mab Biopharma US Limited · Tests: Givastomig, Nivolumab, 5Fluorouracil, Leucovorin, Oxaliplatin A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors NCT04895709Phase 1, Phase 247 sites📍 Clovis📍 Los Angeles📍 Newport Beach Bristol-Myers Squibb · Tests: BMS-986340, BMS-936558-01, Docetaxel, Pumitamig Phase 2 Trial of KN026+KN046±XELOX in HER2-positive Locally Advanced GC NCT06023758Phase 21 site📍 Beijing Peking University · Tests: KN026, KN046, XELOX Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer NCT04511039Phase 11 site📍 Buffalo Roswell Park Cancer Institute · Tests: Trifluridine and Tipiracil Hydrochloride, Talazoparib Tosylate Neoadjuvant Tislelizumab + LM-302 + S-1 or Tislelizumab + SOX for CLDN18.2-Positive Gastric/GEJ Adenocarcinoma NCT07569068Phase 21 site📍 Shanghai Ruijin Hospital · Tests: Tislelizumab, LM-302 and S-1, Tislelizumab combined with oxaliplatin and S-1 DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 16 sites📍 Denver📍 Grand Rapids📍 East Brunswick Duboce Biopharmaceuticals, Inc. · Tests: DBC-664 A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites📍 Birmingham📍 Los Angeles📍 Miami Astellas Pharma Global Development, Inc. · Tests: ASP546C A Study of AK104/Placebo Plus AK109/Placebo And Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma NCT06341335Phase 31 site📍 Beijing Akeso · Tests: cadonilimab, pulocimab, paclitaxel, placebo QLS31905 in Combination With CAPOX Versus Sintilimab in Combination With CAPOX as First-line Treatment in Patients With GC/GEJ NCT07716449Phase 31 site📍 Beijing Qilu Pharmaceutical Co., Ltd. · Tests: QLS31905, Sintilimab, Oxaliplatin, Capecitabine Fruquintinib in Combination With Sintilimab and CAPEOX as First-line Treatment for G/GEJ Cancer NCT06329973Phase 1, Phase 21 site📍 Zhengzhou Henan Cancer Hospital · Tests: Fruquintinib in combination with Sintilimab and CAPEOX Folfox+Irinotecan+Chemort In Esophageal Cancer NCT04656041Phase 23 sites📍 Boston📍 Boston📍 Newton Massachusetts General Hospital · Tests: FOLFOX/ nal-IRI, Paclitaxel, Carboplatin, Proton Radiation Therapy A Phase Ib/II Study of Adebrelimab in Combination with Capecitabine and Oxaliplatin in Cancer NCT06776770Phase 1, Phase 21 site📍 Shenzhen Cancer Hospital Chinese Academy of Medical Science, Shenzhe… · Tests: Adebrelimab Testing Ivonescimab in Combination With Chemotherapy in Advanced or Metastatic Gastric/Gastroesophageal Adenocarcinoma NCT06846346Phase 24 sites📍 Lyon📍 Marseille📍 Reims UNICANCER · Tests: Ivonescimab, FOLFOX regimen, Irinotecan, Paclitaxel
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