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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Head and Neck Squamous Cell Carcinoma

cDNA and Residual Disease After Chemoradiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinomas NCT07178847NA4 sites📍 Aurillac📍 Clermont-Ferrand📍 Lyon Centre Jean Perrin · Tests: blood sampling Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC NCT06510660Phase 21 site📍 Fuzhou Fujian Medical University Union Hospital · Tests: adebrelimab A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors NCT05208762Phase 162 sites📍 Birmingham📍 Birmingham📍 Birmingham Seagen, a wholly owned subsidiary of Pfizer · Tests: PF-08046054, pembrolizumab Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors NCT07360314Phase 19 sites📍 New Haven📍 Huntersville📍 Galveston EMD Serono Research & Development Institute, Inc. · Tests: M7437, M7437 A Trial of the Combination of Afatinib and Palbociclib in Previously Treated Advanced Esophageal Squamous Cell Carcinoma NCT06753747Phase 1, Phase 21 site📍 Chengdu West China Hospital · Tests: Palbociclib, Afatinib(30mg), Afatinib(40mg), Afatinib(RP2D) Neoadjuvant Adebrelimab Plus Chemotherapy for Esophageal Cancer: A Clinical Study NCT07437898Phase 21 site📍 Putian The Affiliated Hospital of Putian University · Tests: Adebrelimab, chemotherapy Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer NCT06173986Phase 1, Phase 21 site📍 Shanghai Shanghai Chest Hospital · Tests: PD-1inhibitor, nab-paclitaxel + cisplatin, Radiotherapy Nimotuzumab Combined With Immunotherapy and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma NCT07601737Phase 21 site📍 Shanghai Shanghai General Hospital, Shanghai Jiao Tong University Sc… · Tests: Nimotuzumab Injection, Tislelizumab, Albumin-Bound Paclitaxel /nab-Paclitaxel, Cisplatin (Or Carboplatin), Radical surg… Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites📍 Tampa📍 Chicago📍 Fairway National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib A Study of DM005 in Patients With Advanced Solid Tumors NCT06515990Phase 1, Phase 26 sites📍 Detroit📍 Dallas📍 Fairfax Doma Biopharmaceutical（Suzhou）Co., Ltd. · Tests: DM005 A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies NCT05473156Phase 1, Phase 21 site📍 Taipei AP Biosciences Inc. · Tests: AP203, AP203 First in Human Study of TUB-030 in Patients With Advanced Solid Tumors NCT06657222Phase 1, Phase 220 sites📍 New Haven📍 Miami📍 Boston Gilead Sciences · Tests: TUB-030 Nimotuzumab Combined With Sintilimab and Chemotherapy for Advanced Esophageal Squamous Cell Carcinoma NCT06718205Phase 21 site📍 Zhengzhou The First Affiliated Hospital of Zhengzhou University · Tests: Nimotuzumab, Sintilimab, Paclitaxel-albumin, Cisplatin Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site📍 Portland OHSU Knight Cancer Institute · Tests: Biospecimen Collection, Immune Checkpoint Inhibitor Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors NCT04777994Phase 130 sites📍 Tucson📍 New Haven📍 Baltimore Calico Life Sciences LLC · Tests: ABBV-CLS-484, Vascular Endothelial Growth Factor Receptor (VEGFR) Tyrosine Kinase Inhibitor (TKI), Programmed Cell Deat… A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors NCT07749586Phase 1, Phase 24 sites📍 New York📍 Huntersville📍 San Antonio Arvinas Inc. · Tests: ARV-6723, Pembrolizumab, SOC A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas. NCT06022029Phase 116 sites📍 Los Angeles📍 Tamarac📍 Canton OncoNano Medicine, Inc. · Tests: ONM-501, Cemiplimab A Clinical Trial Comparing the Efficacy and Safety of Anyouping® and Platinum-based Chemotherapy With or Without Enlituo® in Advanced Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma. NCT07791745Phase 2, Phase 31 site📍 Shanghai Taizhou Mabtech Pharmaceutical Co.,Ltd · Tests: Enlituo® + Anyouping® + PBC, Placebo-Enlituo + Anyouping® + PBC Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC (KEYSTONE-002) NCT04807673Phase 31 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: Pembrolizumab, Paclitaxel, Cisplatin, neoadjuvant chemoradiotherapy A Study of Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell Carcinoma NCT06354530Phase 2, Phase 31 site📍 Chongqing Army Medical Center of PLA · Tests: anlotinib, Thoracic radiotherapy A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors NCT07277413Phase 123 sites📍 Goodyear📍 Phoenix📍 Duarte IDEAYA Biosciences · Tests: IDE892, IDE397 A Study of IDP-001 in Advanced or Metastatic Solid Tumors NCT07602842Phase 1, Phase 26 sites📍 Los Angeles📍 Sarasota📍 Indianapolis InduPro, Inc. · Tests: IDP-001 Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: SX-682, DTX Pembrolizumab and Induction Chemotherapy in Locally Advanced HNSCC NCT05272696Phase 21 site📍 Guangzhou Guangdong Provincial People's Hospital · Tests: Nab-paclitaxel, cisplatin and Pembrolizumab combination, surgery, Adjuvant Chemoradiotherapy, Radical concurrent chemor… A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors NCT04895709Phase 1, Phase 247 sites📍 Clovis📍 Los Angeles📍 Newport Beach Bristol-Myers Squibb · Tests: BMS-986340, BMS-936558-01, Docetaxel, Pumitamig Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC NCT06601309Phase 21 site📍 Fuzhou Fujian Medical University Union Hospital · Tests: Serplulimab, Paclitaxel+Cisplatin (Neoadjuvant Chemotherapy), Paclitaxel+Cisplatin(Concurrent Chemoradiotherapy), Radio… A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC NCT07385001Phase 1, Phase 21 site📍 Xi'an Tang-Du Hospital · Tests: AK112, AK112, AK112 + Neoadjuvant chemotherapy A Study of Chemoradiation in Combination with Tislelizumab As First Line Treatment in Participants with Advanced Esophageal Squamous Cell Carcinoma NCT05919030Phase 31 site📍 Wuhan Renmin Hospital of Wuhan University · Tests: Intensity-modulated radiotherapy (IMRT), Tislelizumab, Cisplatin, Nab paclitaxel Sintilimab and Chemotherapy Sequential Radiotherapy in Advanced Esophageal Cancer NCT06138028Phase 2, Phase 32 sites📍 Qingdao📍 Qingdao Qingdao Central Hospital · Tests: TP regimen (cis-platinum ; Tocetaxel ) combined with PD-1 inhibitors（Sintilimab） Induction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal Cancer NCT06421376Phase 23 sites📍 Anyang📍 Xinxiang📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Cardonilizumab, Chemoradiotherapy ±immunotherapy, Radical surgery
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