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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Intrahepatic Cholangiocarcinoma

Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma NCT07780838Phase 21 site๐Ÿ“ Columbus Ohio State University Comprehensive Cancer Center ยท Tests: Biospecimen Collection, Cisplatin, Computed Tomography, Durvalumab, Gemcitabine Liver Transplantation in Intrahepatic Cholangiocarcinoma NCT06140134n/a2 sites๐Ÿ“ Newark๐Ÿ“ Newark Rutgers, The State University of New Jersey ยท Tests: Liver Transplant Safety and Efficacy of CD160-Enhanced Autologous Antigen-Specific T-Cells (BTC-Ag-T) in Advanced Biliary Tract Cancer NCT07614061Phase 11 site๐Ÿ“ Shanghai Shanghai Zhongshan Hospital ยท Tests: BTC-Ag-T (ACH-AgT001), Cyclophosphamide and Fludarabine Personalized Tumor Neoantigen mRNA Therapy for Advanced Intrahepatic Cholangiocarcinoma NCT06956716Phase 1, Phase 21 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: individualized anti-tumor new antigen iNeo-Vac-R01 injection, Gemcitabine + cisplatin (GP), Sintilimab injection Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma: a Phase 2 Study(HAIC-quad Trial) NCT06859684Phase 21 site๐Ÿ“ Chengdu West China Hospital ยท Tests: Durvalumab, hepatic arterial infusion chemotherapy (HAIC), Lenvatinib HYPERION CCA: a Phase 2 Trial of Systemic Therapy With or Without Liver-directed Radiation Therapy for Patients With Advanced Intrahepatic Cholangiocarcinoma NCT06858735Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Durvalumab, Gemcitabine, Cisplatin TACE Combined With Tislelizumab in Patients With Advanced Intrahepatic Cholangiocarcinoma NCT04954781Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Tislelizumab, TACE Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma NCT06058663Phase 11 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Angiography, Biopsy, Biospecimen Collection, Computed Tomography, Durvalumab Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio NCT05655949Phase 21 site๐Ÿ“ Boston Beth Israel Deaconess Medical Center ยท Tests: Gemcitabine, Cisplatin, Durvalumab, Yttrium-90 A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer NCT07265674Phase 318 sites๐Ÿ“ Duarte๐Ÿ“ Orange๐Ÿ“ Santa Monica J-Pharma Co., Ltd. ยท Tests: Nanvuranlat, Physician's Best Choice A Clinical Study to Evaluate the Efficacy and Safety of VG2025 in Intrahepatic Cholangiocarcinoma NCT07522476Phase 21 site๐Ÿ“ Hangzhou Virogin Biotech Ltd. ยท Tests: VG2025 HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma NCT04353375Phase 2, Phase 31 site๐Ÿ“ Beijing Hutchmed ยท Tests: HMPL-453 A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4ฮฑ srRNA in Treating Advanced ICC Patients NCT06583993EARLY Phase 11 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: HNF4ฮฑ srRNA Perioperative Retlirafusp Alfa(Anti-PD-L1/TGF-ฮฒ Bifunctional Fusion Protein) Plus Famitinib and GEMOX-Based Hepatic Arterial Infusion Chemotherapy for Locally Advanced Intrahepatic Cholangiocarcinoma: A Multicenter, Single-Arm, Exploratory Phase II Trial NCT07847710Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: Retlirafusp alfa, Famitinib malate, Gemcitabine & oxaliplatin, Capecitabine, S-1 A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement NCT06728410Phase 23 sites๐Ÿ“ Birmingham๐Ÿ“ Buffalo๐Ÿ“ Columbus Mehmet Akce ยท Tests: Pemigatinib, Durvalumab Combined Therapy Using Gemcitabine and Cisplatin Chemotherapy, Lenvatinib and Adebrelimab for Patients With Advanced and Unresectable Intrahepatic Cholangiocarcinoma NCT06298968Phase 21 site๐Ÿ“ Guangzhou Nanfang Hospital, Southern Medical University ยท Tests: combined therapy using gemcitabine and cisplatin chemotherapy, Lenvatinib and Adebrelimab Chemotherapy Combined with Immunotherapy and Targeted Therapy in Cholangiocarcinoma NCT06718257n/a1 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Gemcitabine combined with cisplatin or oxaliplatin, Gemcitabine combined with cisplatin or oxaliplatin, PD-1/L1 and TKIโ€ฆ Liver Transplantation for Locally Advanced Intrahepatic Cholangiocarcinoma After SIRT and Chemotherapy NCT06910722NA1 site๐Ÿ“ Clichy-sous-Bois Assistance Publique - Hรดpitaux de Paris ยท Tests: Liver transplant Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study NCT05342194Phase 31 site๐Ÿ“ Shanghai Shanghai Junshi Bioscience Co., Ltd. ยท Tests: Toripalimab, Lenvatinib mesylate capsules, Placebo IV, Oral placebo, Oxaliplatin for injection Cryoablation Combined With Lenvatinib Plus Tislelizumab Compared With FOLFOX in Patients With Advanced Intrahepatic Cholangiocarcinoma (CASTLE-ZS-01) NCT06860477Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Tislelizumab, Lenvatinib, cryoablation, FOLFOX (5-fluorouracil, Leucovorin, Oxaliplatin) Lenvatinib Plus Sintilimab in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Liver Cancer NCT05010681Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Sintilimab, Lenvatinib A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors NCT07169734Phase 1, Phase 241 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ New Haven Alentis Therapeutics AG ยท Tests: ALE.P03, ALE.P03, ALE.P03 Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer NCT06282575Phase 3185 sites๐Ÿ“ Duarte๐Ÿ“ Lone Tree๐Ÿ“ Orlando Jazz Pharmaceuticals ยท Tests: Zanidatamab, Cisplatin, Gemcitabine, Pembrolizumab, Durvalumab Phase II Clinical Study of GemOX Hepatic Arterial Infusion Combined with Lenvatinib and Toripalimab for Advanced and Unresectable Intrahepatic Cholangiocarcinoma and Gallbladder Cancer NCT06852287Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: chemotherapy with gemcitabine and oxaliplatin; small molecure TKI lenvatinib; immune-checkpoint inhibitor toripalimab. The Purpose of This Research Study is to See if Combining Gemcitabine, Cisplatin and Durvalumab Chemotherapy Treatments With a Direct Tumor Therapy Yittrium-90 (Y-90) Will Work Better Together to Shrink Tumors and Control Cancer NCT05422690Phase 21 site๐Ÿ“ Fairfax Inova Health Care Services ยท Tests: Induction Chemotherapy Triplet Therapy, Concurrent Y-90 treatment, Consolidation Doublet Therapy: Cryoablation Combined with Anti-PD-1 Antibody in Patients with Advanced Intrahepatic Cholangiocarcinoma NCT04299581Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Camrelizumab, US/CT-guided Percutaneous Cryoablation A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors NCT07020221Phase 1, Phase 220 sites๐Ÿ“ Los Angeles๐Ÿ“ Baltimore๐Ÿ“ Boston Verastem, Inc. ยท Tests: VS-7375, Cetuximab, Carboplatin + Pemetrexed + Pembrolizumab, Gemcitabine + Nab-paclitaxel, Pembrolizumab Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract Cancer NCT07641036Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-HC01 dual-target CARNK cells, Fludarabine, Cyclophosphamide Cryoablation Combined With Lenvatinib Plus QL1706 (Iparomlimab/Tuvonralimab) in Patients With Advanced Intrahepatic Cholangiocarcinoma NCT07070700Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: QL1706 (bispecific antibody targeting PD-1 and CLTA-4), Lenvatinib, cryoablation Clinical Study of VG161 in Advanced Intrahepatic Cholangiocarcinoma NCT06746480Phase 21 site๐Ÿ“ Hangzhou CNBG-Virogin Biotech (Shanghai) Ltd. ยท Tests: Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell))
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