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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Malignant Tumour

MT027 in Patients With Advanced Peritoneal Malignancies or Abdominal Metastatic Solid Tumors NCT06912152Phase 11 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: MT027 CAR-T cells A Clinical Trial of MK-2010 With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Solid Tumors (MK-2010) NCT07785609Phase 24 sites๐Ÿ“ San Antonio๐Ÿ“ Hong Kong๐Ÿ“ Bellinzona Merck Sharp & Dohme LLC ยท Tests: MK-2010, Sacituzumab tirumotecan, Histamine H1 Receptor Antagonist, Histamine H2 Receptor Antagonist, Acetaminophen (orโ€ฆ A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies NCT04678648Phase 13 sites๐Ÿ“ Los Angeles๐Ÿ“ Denver๐Ÿ“ Nashville RasCal Therapeutics, Inc. ยท Tests: RSC-1255 Dose Escalation, RSC-1255 Dose Expansion Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid Cancers NCT06606990Phase 11 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Advanced Solid Tumors NCT07387068Phase 112 sites๐Ÿ“ New Haven๐Ÿ“ Grand Rapids๐Ÿ“ Lake Success Genmab ยท Tests: GEN1079 Phase 1 Study of MST-168 in Participants With Advanced Solid Malignant Tumors NCT07644650Phase 11 site๐Ÿ“ Shanghai Mabsoft Therapeutics (Shanghai) Co., Ltd. ยท Tests: MST-168 A Phase I/II Study of LM-101 Injection in Patients With Advanced Malignant Tumors NCT05615974Phase 1, Phase 25 sites๐Ÿ“ Guangzhou๐Ÿ“ Wuhan๐Ÿ“ Linyi LaNova Medicines Limited ยท Tests: LM101, Toripalimab, Rituximab Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors NCT04222413Phase 12 sites๐Ÿ“ Fairway๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Metarrestin JSKN022 in Subjects With Advanced Malignant Solid Tumors NCT07292402Phase 11 site๐Ÿ“ Guangzhou Jiangsu Alphamab Biopharmaceuticals Co., Ltd ยท Tests: JSKN022 CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site๐Ÿ“ Chicago Northwestern University ยท Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies NCT04282044Phase 13 sites๐Ÿ“ Scottsdale๐Ÿ“ La Jolla๐Ÿ“ Stanford BioEclipse Therapeutics ยท Tests: CRX100 suspension for infusion, Fludarabine, Cyclophosphamide Study of MHB088C for Patients With Advanced Solid Malignant Tumors NCT07102004Phase 1, Phase 21 site๐Ÿ“ Beijing Qilu Pharmaceutical Co., Ltd. ยท Tests: MHB088C for Injection Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma NCT07126509NA1 site๐Ÿ“ Chicago University of Chicago ยท Tests: Partial Pleurectomy Siltuximab for the Prevention of Severe Immune-Related Adverse Events During Immune Checkpoint Inhibitor Rechallenge in Patients With Advanced Cancer, CIRES Trial NCT06470971Phase 21 site๐Ÿ“ Columbus Yuanquan Yang ยท Tests: Anti-PD-L1 Monoclonal Antibody, Anti-PD1 Monoclonal Antibody, Biopsy, Biospecimen Collection, Bone Scan Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors NCT04879121Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Larotrectinib Sulfate Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors NCT05141474EARLY Phase 11 site๐Ÿ“ Barcelona Vall d'Hebron Institute of Oncology ยท Tests: NEXTGEN-TIL, Non-myeloablative Lymphodepletion (NMA-LD) Regimen, Interleukin-2 Safety, Tolerability, and Preliminary Antitumor Activity of Cationic Peptide-IL22BP mRNA in Advanced Solid Tumors NCT07583654Phase 11 site๐Ÿ“ Chengdu West China Hospital ยท Tests: CP-IL22BP mRNA intratumorally injection Using Neoantigen Peptide Vaccine/neoantigen-based DC to Treat Advanced Malignant Solid Tumors NCT05749627NA1 site๐Ÿ“ Nanchang The First Affiliated Hospital of Nanchang University ยท Tests: Neoantigen peptide vaccine, Neoantigen-based DC immune preparation A Study of Osimertinib-based Adaptive Treatment Guided by ctDNA EGFRm+ Monitoring in NSCLC NCT07058519Phase 21 site๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: Osimertinib-based adaptive treatment, Osimertinib 80 MG Anti-HER2 CAR-T Cell Injection in Patients With HER2-positive Advanced Malignant Solid Tumors NCT06658951NA1 site๐Ÿ“ Zhengzhou UTC Therapeutics Inc. ยท Tests: Anti-HER2 CAR-T cells Atamparib in Patients With Advanced Solid Tumors NCT07374419Phase 1, Phase 21 site๐Ÿ“ Shanghai Nerviano Medical Sciences (Shanghai) Ltd. ยท Tests: atamparib escalation levels, atamparib RP2D AZD5305 hADME in Patients With Advanced Solid Malignancies NCT06713369Phase 12 sites๐Ÿ“ Liverpool๐Ÿ“ Manchester AstraZeneca ยท Tests: Saruparib (AZD5305), [14C]-AZD5305 microtracer, [14C]-AZD5305 (therapeutic dose) Efficacy and Safety of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma NCT07885319Phase 1, Phase 23 sites๐Ÿ“ Shanghai๐Ÿ“ Shanghai๐Ÿ“ Chengdu Ruijin Hospital ยท Tests: Ivonescimab Combined With Chemotherapy MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma NCT06277154Phase 21 site๐Ÿ“ Guangzhou HRYZ Biotech Co. ยท Tests: MASCT-I, Doxorubicin, Ifosfamide A Study Evaluating the Safety and Efficacy of AUR107 in Patients With Relapsed Advanced Malignancies (SHAKTI-1) NCT05865002Phase 137 sites๐Ÿ“ Vijayawada๐Ÿ“ Visakhapatnam๐Ÿ“ Chandigarh Aurigene Discovery Technologies Limited ยท Tests: AUR107 A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of SSGJ-705 Monotherapy in Patients with Advanced Malignant Tumors NCT06390774Phase 11 site๐Ÿ“ Jinan Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. ยท Tests: SSGJ-705 Study of LM-299 in Subjects Advanced Malignant Tumors NCT06650566Phase 1, Phase 26 sites๐Ÿ“ Perth๐Ÿ“ Xinxiang๐Ÿ“ Liaocheng LaNova Medicines Limited ยท Tests: LM-299 Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT) NCT07026422Phase 21 site๐Ÿ“ Jinan Shandong Cancer Hospital and Institute ยท Tests: Total neoadjuvant therapy integrating iparomlimab/tuvonralimab with chemoradiotherapy Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Biospecimen Collection, Immune Checkpoint Inhibitor An Open-label, Randomized Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of the Combination Therapy of SLC-3010 and Axitinib Compared to Axitinib Monotherapy as a Second-line Treatment for Locally Advanced or Metastatic Clear Cell Renal Cell Carcinoma NCT07469683Phase 21 site๐Ÿ“ Seoul Yonsei University ยท Tests: SLC-3010 + Axitinib, Axitinib
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