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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Soft Tissue Sarcoma

Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors NCT04557449Phase 1, Phase 239 sites📍 Los Angeles📍 New Haven📍 New Haven Pfizer · Tests: PF-07220060, Letrozole, Fulvestrant, Midazolam, Enzalutamide Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC NCT07145450Phase 1, Phase 210 sites📍 Copenhagen📍 Berlin📍 Dresden Anocca AB · Tests: ANOC-001 (TCR-T cells targeting KRAS G12V mutation presented by specific HLA alleles), ANOC-002 (TCR-T cells targeting … Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors NCT04222413Phase 12 sites📍 Fairway📍 Bethesda National Cancer Institute (NCI) · Tests: Metarrestin Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies NCT04282044Phase 13 sites📍 Scottsdale📍 La Jolla📍 Stanford BioEclipse Therapeutics · Tests: CRX100 suspension for infusion, Fludarabine, Cyclophosphamide X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma NCT04389281Phase 14 sites📍 Washington D.C.📍 Charlotte📍 Durham Immunolight, LLC · Tests: X-PACT Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe Trial NCT07227571Phase 11 site📍 Seattle Fred Hutchinson Cancer Center · Tests: FH FOLR1 ST CAR T-cells, Leukapheresis, Fludarabine, Cyclophosphamide, Echocardiography Test A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004) NCT06345729Phase 3246 sites📍 Bakersfield📍 Beverly Hills📍 Stamford Merck Sharp & Dohme LLC · Tests: Calderasib, Placebo, Pembrolizumab MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma NCT06277154Phase 21 site📍 Guangzhou HRYZ Biotech Co. · Tests: MASCT-I, Doxorubicin, Ifosfamide Sarcoma Preoperative Radiation With Simultaneous INTegrated Boost (SPRINT) NCT05761054NA1 site📍 Florence Azienda Ospedaliero-Universitaria Careggi · Tests: RT Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor NCT05146440Phase 1, Phase 24 sites📍 Zaragoza📍 Barcelona📍 Barcelona Grupo Espanol de Investigacion en Sarcomas · Tests: PM14 Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma NCT06528769Phase 21 site📍 Columbus Gabriel Tinoco · Tests: all-trans retinoic acid, Cemiplimab, Computed Tomography, Magnetic resonance imaging, Biospecimen Collection Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Avapritinib A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma NCT06942442Phase 24 sites📍 Los Angeles📍 Chicago📍 New York Sarcoma Alliance for Research through Collaboration · Tests: Physician's Choice, Tebentafusp Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc) NCT06114004Phase 211 sites📍 Santa Cruz de Tenerife📍 Barcelona📍 Barcelona Asociación Europea y Latinoamericana SELNET para la Investi… · Tests: Selinexor 20 MG, Gemcitabine A Phase 2 Pilot Study to Evaluate the Safety and the Anti-Tumour Activity of the Myc Inhibitor OMO-103 Administered Intravenously in Patients With Advanced High-Grade Osteosarcoma NCT06650514Phase 21 site📍 Barcelona Vall d'Hebron Institute of Oncology · Tests: OMO-103 A Study of PHST001 in Advanced Solid Tumors NCT06840886Phase 120 sites📍 Beverly Hills📍 Los Angeles📍 Palo Alto Pheast Therapeutics · Tests: PHST001, Paclitaxel, Topotecan, Doxorubicin, FOLFIRI SAINT:Trabectedin, Ipilimumab and Nivolumab for Previously Treated Advanced Soft Tissue Sarcoma NCT03138161Phase 1, Phase 21 site📍 Santa Monica Sarcoma Oncology Research Center, LLC · Tests: Trabectedin, Ipilimumab, Nivolumab Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma NCT07291297Phase 22 sites📍 Charlotte📍 Winston-Salem Wake Forest University Health Sciences · Tests: Metformin Hydrochloride ER A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, Dedifferentiated Liposarcoma, or Angiosarcoma NCT05607095Phase 12 sites📍 Harrison📍 New York Memorial Sloan Kettering Cancer Center · Tests: Lifileucel (LN-144/LN-145) Study of the Impact of Digital Health Interventions on Symptom & Side-Effect Management in Metastatic Sarcoma Patients NCT07642375NA11 sites📍 Athens📍 Athens📍 Athens CareAcross · Tests: Digital support First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors NCT06644755Phase 17 sites📍 Boston📍 New York📍 Nashville Daiichi Sankyo · Tests: DS-2243a IDOV-Immune for Advanced Solid Tumors NCT06910657Phase 15 sites📍 St Louis📍 Houston📍 San Antonio ViroMissile, Inc. · Tests: IDOV-Immune (oncolytic vaccinia virus) IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors NCT05039801Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: Bevacizumab, Glutaminase-1 Inhibitor IACS-6274, Paclitaxel, Capivasertib Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer NCT07067255Phase 1, Phase 21 site📍 Beijing Essen Biotech · Tests: GPC3 CD146 CAR-T cells Evaluate the Safety and Clinical Activity of HH2853 NCT04390737Phase 1, Phase 225 sites📍 Phoenix📍 Jacksonville📍 Rochester Haihe Biopharma Co., Ltd. · Tests: HH2853 Tablets This is a Randomized Study of Early Involvement of Palliative Care Along Side Standard Treatment Versus Standard Treatment Alone in Newly Diagnosed Patients With Advanced or Metastatic Soft Tissue Sarcoma (SARQUALITY) NCT06805669NA1 site📍 Toronto Mount Sinai Hospital, Canada · Tests: Early referral to palliative care, Standard Treatment Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue Sarcoma NCT04535271Phase 21 site📍 Santa Monica Sarcoma Oncology Research Center, LLC · Tests: Trabectedin A Study Evaluating the Efficacy and Safety of Risvutatug Rezetecan in Participants With Advanced Sarcomas (EMBOLD Sarcoma-202) NCT07602777Phase 1, Phase 213 sites📍 West Valley City📍 Toronto📍 Montreal GlaxoSmithKline · Tests: Ris-Rez, G-CSF PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma NCT04303117Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: PDS01ADC, M7824 Lenvatinib for Advanced Bone and Soft Tissue Sarcoma NCT05617859Phase 21 site📍 Zhengzhou Henan Cancer Hospital · Tests: Lenvatinib mesylate capsule
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