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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Advanced or Metastatic Non-small Cell Lung Cancer

A Phase I Study of CFT8919 in Patients With Advanced NSCLC NCT06641609Phase 11 site๐Ÿ“ Hangzhou Betta Pharmaceuticals Co., Ltd. ยท Tests: Dose-Escalation (Phase Ia) CFT8919 capsule, Dose-Expansion (Phase Ib) CFT8919 capsule, Cohort-Expansion (Phase Ic) CFT8โ€ฆ A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation. NCT05967689Phase 280 sites๐Ÿ“ Birmingham๐Ÿ“ Duarte๐Ÿ“ Boston Taiho Oncology, Inc. ยท Tests: TAS6417, CYP Cocktail, Transporter Cocktail A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2) NCT06452277Phase 3279 sites๐Ÿ“ Newport Beach๐Ÿ“ San Diego๐Ÿ“ San Francisco Bayer ยท Tests: Sevabertinib, Pembrolizumab, Cisplatin, Carboplatin, Pemetrexed GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer NCT07017829Phase 21 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Anti-CFH Monoclonal Antibody GT103, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test A Phase 2 Clinical Study of Combination Therapy With ABSK043 and Firmonertinib NCT06668103Phase 25 sites๐Ÿ“ Hefei๐Ÿ“ Harbin๐Ÿ“ Wuhan Abbisko Therapeutics Co, Ltd ยท Tests: ABSK043 in combination with Firmonertinib AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors NCT07094113Phase 139 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Atlanta Amgen ยท Tests: AMG 410, Pembrolizumab, Panitumumab A Study of Osimertinib-based Adaptive Treatment Guided by ctDNA EGFRm+ Monitoring in NSCLC NCT07058519Phase 21 site๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: Osimertinib-based adaptive treatment, Osimertinib 80 MG A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) โ‰ฅ50% (MK-1084-004/KANDLELIT-004) NCT06345729Phase 3246 sites๐Ÿ“ Bakersfield๐Ÿ“ Beverly Hills๐Ÿ“ Stamford Merck Sharp & Dohme LLC ยท Tests: Calderasib, Placebo, Pembrolizumab GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors NCT04977453Phase 1, Phase 213 sites๐Ÿ“ New York๐Ÿ“ New York๐Ÿ“ Huntersville GI Innovation, Inc. ยท Tests: GI-101, Pembrolizumab (KEYTRUDAยฎ), Lenvatinib, GI-101A A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations NCT06430437Phase 31 site๐Ÿ“ Shanghai Jiangsu HengRui Medicine Co., Ltd. ยท Tests: SHR-A1811, PD-1/PD-L1 inhibitorsใ€Pemetrexed/ Paclitaxelใ€Carboplatin/ Cisplatin ASKC202 Combined With Limertinib Versus Platinum-based Chemotherapy in Treatment of Locally Advanced or Metastatic NSCLC With MET Amplification/Overexpression After Failure of EGFR-TKI Therapy NCT07109531Phase 31 site๐Ÿ“ Shanghai Jiangsu Aosaikang Pharmaceutical Co., Ltd. ยท Tests: ASKC202+ Limertinib, Pemetrexed + Cisplatin /Carboplatin Vebreltinib Plus Furmonertinib in Patients With EGFR-mutated Advanced Non-small Cell Lung Cancer and High PD-L1 Expression NCT07655622Phase 1, Phase 21 site๐Ÿ“ Nanchang Second Affiliated Hospital of Nanchang University ยท Tests: Vebreltinib, Furmonertinib 80mg A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies NCT05473156Phase 1, Phase 21 site๐Ÿ“ Taipei AP Biosciences Inc. ยท Tests: AP203, AP203 Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Biospecimen Collection, Immune Checkpoint Inhibitor Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors NCT04777994Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ New Haven๐Ÿ“ Baltimore Calico Life Sciences LLC ยท Tests: ABBV-CLS-484, Vascular Endothelial Growth Factor Receptor (VEGFR) Tyrosine Kinase Inhibitor (TKI), Programmed Cell Deatโ€ฆ Nelmastobart in Combination With Docetaxel in Non Small Cell Lung Cancer NCT07306624Phase 25 sites๐Ÿ“ Gyeonggi-do๐Ÿ“ Seoul๐Ÿ“ Seoul STCube, Inc. ยท Tests: Nelmastobart and Docetaxel Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations NCT06772623Phase 1, Phase 2126 sites๐Ÿ“ Phoenix๐Ÿ“ Fullerton๐Ÿ“ Oxnard AbbVie ยท Tests: Telisotuzumab Adizutecan, Budigalimab, Pembrolizumab, Pembrolizumab, Carboplatin Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) NCT07149649Phase 2, Phase 311 sites๐Ÿ“ Aarau๐Ÿ“ Aarau๐Ÿ“ Baden Swiss Cancer Institute ยท Tests: Magnesiocard, Magnesium Diasporal, Microcrystalline cellulose, Isotonic saline solution 0.9% A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer NCT06512051Phase 1, Phase 21 site๐Ÿ“ Beijing Shanghai Hengrui Pharmaceutical Co., Ltd. ยท Tests: SHR-A2102 for Injection, Adebrelimab Injection, Cisplatin injection, Carboplatin injection, Bevacizumab Injection Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer NCT05168566Phase 231 sites๐Ÿ“ Glendale๐Ÿ“ Washington D.C.๐Ÿ“ Athens Teligene US ยท Tests: Sutetinib Maleate Capsule Study of MT-302 in Adults With Advanced or Metastatic Epithelial Tumors NCT05969041Phase 16 sites๐Ÿ“ Darlinghurst๐Ÿ“ Randwick๐Ÿ“ Westmead Myeloid Therapeutics ยท Tests: MT-302 (A) A Study of IDP-001 in Advanced or Metastatic Solid Tumors NCT07602842Phase 1, Phase 26 sites๐Ÿ“ Los Angeles๐Ÿ“ Sarasota๐Ÿ“ Indianapolis InduPro, Inc. ยท Tests: IDP-001 Disitamab Vedotin in Combination with Tislelizumab and Bevacizumab in a Phase II Clinical Study of Locally Advanced or Metastatic Non-small Cell Lung Cancer with HER2 Mutation/amplification/expression NCT06749860Phase 21 site๐Ÿ“ Shanghai Shanghai Pulmonary Hospital, Shanghai, China ยท Tests: Disitamab Vedotin + tislelizumab + bevacizumab Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites๐Ÿ“ Scottsdale๐Ÿ“ Bethesda๐Ÿ“ Columbus Novartis Pharmaceuticals ยท Tests: dabrafenib, trametinib A Phase 1 Study of LNCB74 in Advanced Solid Tumors NCT06774963Phase 114 sites๐Ÿ“ Newport Beach๐Ÿ“ Edgewood๐Ÿ“ Boston NextCure, Inc. ยท Tests: LNCB74 Sotorasib in Previously Treated Locally Advanced or Metastatic NSCLC Subjects With Mutated KRAS p.G12C NCT05631249Phase 25 sites๐Ÿ“ Lyon๐Ÿ“ Marseille๐Ÿ“ Paris Gustave Roussy, Cancer Campus, Grand Paris ยท Tests: Sotorasib 120Mg Tab Andamertinib With or Without Platinum-doublet Chemotherapy Versus Platinum-doublet Chemotherapy in Patients With NSCLC Harboring Atypical EGFR Mutations NCT07336732Phase 21 site๐Ÿ“ Guangzhou Avistone Biotechnology Co., Ltd. ยท Tests: PLB1004 TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Lung Cancer NCT06538012Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: Tumor Infiltrating Lymphocytes (TIL), Cyclophosphamide, Fludarabine, Interleukin-2, Pembrolizumab D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure NCT06300177Phase 386 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Beijing Chia Tai Tianqing Pharmaceutical Group Co., Ltd. ยท Tests: D-1553 Tablet, Docetaxel injection A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer NCT07155187Phase 2, Phase 3117 sites๐Ÿ“ Springdale๐Ÿ“ Duarte๐Ÿ“ Irvine AbbVie ยท Tests: Telisotuzumab Adizutecan, Standard of Care, Osimertinib
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