🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Bipolar I Disorder

An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania NCT07288320Phase 211 sites📍 Little Rock📍 Cerritos📍 Garden Grove Neurocrine Biosciences · Tests: NBI-1117568, Placebo A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3) NCT06929273Phase 3184 sites📍 Glendale📍 Scottsdale📍 Tucson Bristol-Myers Squibb · Tests: KarXT, Lithium, Valproate, Lamotrigine Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE. NCT07494305Phase 226 sites📍 Bentonville📍 Little Rock📍 Bellflower LB Pharmaceuticals Inc. · Tests: LB-102, Placebo Brexpiprazole Treatment for Bipolar I Depression NCT04569448Phase 33 sites📍 Hamilton📍 Montreal📍 Montreal Douglas Mental Health University Institute · Tests: Brexpiprazole Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II. NCT07412132Phase 31 site📍 São Paulo University of Sao Paulo · Tests: Lacosamide, Placebo Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder NCT07213466Phase 41 site📍 Rochester Mayo Clinic · Tests: Group Therapy Program, semaglutide, Phentermine-Topiramate, naltrexone and bupropion (combination) Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder NCT05025605Phase 15 sites📍 Anaheim📍 Hialeah📍 Atlanta BioXcel Therapeutics Inc · Tests: BXCL501 80 Micrograms, Placebo Film, BXCL501 120 Micrograms, BXCL501 60 Micrograms Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT) NCT07569198Phase 21 site📍 Toronto Joshua Rosenblat · Tests: Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT) Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression NCT07108257NA1 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: ExAblate Neuro 4000 Norwegian Mental Illness Heart Health Study NCT07085923NA1 site📍 Oslo Madeleine Elisabeth Angelsen · Tests: Lifestyle Intervention Biocollection on Peripheral Inflammation NCT05934474n/a1 site📍 Nantes Nantes University Hospital · Tests: Peripheral venipuncture blood sampling, as part of standard care procedures, Interview with a psychiatrist Feasibility and Preliminary Results of the Efficacy of Blue-Blocking Glasses on Manic Symptoms in Bipolar Disorder NCT07194278NA1 site📍 Paris Centre Hospitalier St Anne · Tests: Blue-blocking glasses Safety and Tolerability of Open-Labeled Iloperidone in Adolescents NCT05648591Phase 411 sites📍 Dothan📍 Little Rock📍 Denver Vanda Pharmaceuticals · Tests: Iloperidone Safety and Feasibility of DBS for Bipolar Depression NCT07745374NA1 site📍 New York Icahn School of Medicine at Mount Sinai · Tests: Medtronic Percept PC DBS system Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder NCT05303064Phase 347 sites📍 Dothan📍 Little Rock📍 Encino Alkermes, Inc. · Tests: OLZ/SAM, Olanzapine SYNCED - SYNChronized Eating in Bipolar Depression Study NCT06560957NA1 site📍 Ottawa University of Ottawa · Tests: Time restricted eating, Eating ad libitum with nutritional counselling Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine NCT07185815Phase 1, Phase 26 sites📍 Ahmedabad📍 Ahmedabad📍 Beersheba Mapi Pharma Ltd. · Tests: Cariprazine Depot, Cariprazine Depot, Cariprazine Depot MTD, Oral Cariprazine 3 mg/day A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder NCT07540338Phase 1, Phase 21 site📍 Boston Alzamend Neuro, Inc. · Tests: AL001, Lithium carbonate A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine NCT07140913Phase 3104 sites📍 Bentonville📍 Little Rock📍 Bellflower Bristol-Myers Squibb · Tests: Xanomeline/Trospium Chloride, Placebo Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT NCT07211750NA1 site📍 Leuven KU Leuven · Tests: integrated care intervention tailored to the needs of older adults leaving at home with mood disorders and multimorbidi… Melatonin and Response to Lithium NCT05878730n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: urine collection, Level of Proteins, Level of mRNA and miRNA, Level of plasmatic and intraerythrocytic lithium A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder. NCT04777357Phase 381 sites📍 Bentonville📍 Anaheim📍 Beverly Hills AbbVie · Tests: Cariprazine, Placebo Socio-cognitive and Biological Responses to Maltreatment NCT07101107n/a1 site📍 Innsbruck Medical University Innsbruck Decoding Emotional Dynamics in Bipolar Disorder NCT07221864NA1 site📍 Tulsa Laureate Institute for Brain Research, Inc. · Tests: Think and Regulate Affective State Task The Bipolar Lithium Imaging Scan Study. NCT06134349n/a1 site📍 Leiden Leiden University Medical Center · Tests: Lithium MR imaging Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients NCT06372964Phase 368 sites📍 Dothan📍 Little Rock📍 Anaheim Intra-Cellular Therapies, Inc. · Tests: Lumateperone, Placebo A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2) NCT06951711Phase 385 sites📍 Little Rock📍 Rogers📍 Culver City Bristol-Myers Squibb · Tests: KarXT, Placebo NMDA Receptor Modulation for the Treatment of Bipolar I Disorder NCT05977023Phase 21 site📍 Taichung China Medical University Hospital · Tests: NMDAE, Placebo Cap Exercise and Olanzapine-samidorphan NCT06740890Phase 41 site📍 New York New York State Psychiatric Institute · Tests: Olanzapine-samidorphan + exercise Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder NCT06221852NA1 site📍 Belmont Mclean Hospital · Tests: Ketogenic diet, Dietary Guidelines for Americans
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy