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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Bone Marrow Failure Syndromes

Investigation of the Genetics of Hematologic Diseases NCT02720679n/a1 site๐Ÿ“ Memphis St. Jude Children's Research Hospital CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia NCT03896269Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Liposome-encapsulated Daunorubicin-Cytarabine CD7 CAR-T Bridging to alloHSCT for Severe Aplastic Anemia NCT06633328EARLY Phase 11 site๐Ÿ“ Hanzhou Zhejiang University ยท Tests: CD7 CAR-T cells injection, Allogeneic hematopoietic stem cell transplantation TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Non-Malignant Hematological Disorders in Children NCT04356469Phase 21 site๐Ÿ“ St. Petersburg Johns Hopkins All Children's Hospital ยท Tests: Haploidentical Hematopoietic Cell Transplantation Role of Acetaldehyde in the Development of Oral Cancer NCT05973656NA1 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Alcohol, Biospecimen Collection, Breath Test Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency NCT06090669Phase 11 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: TruSight Oncology, imatinib Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium NCT05343572EARLY Phase 11 site๐Ÿ“ Orange Hugh Taylor ยท Tests: Plerixafor Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC NCT04528355n/a1 site๐Ÿ“ Pittsburgh Paul Szabolcs ยท Tests: data collection A Multicenter, Randomized, Open-Label Study of Haplo-Cord HSCT for the Treatment of Aplastic Anemia NCT07499284NA4 sites๐Ÿ“ Suzhou๐Ÿ“ Suzhou๐Ÿ“ Xuzhou The First Affiliated Hospital of Soochow University ยท Tests: Haploidentical hematopoietic cell transplantation combined with unrelated cord blood stem cells, Haploidentical hematopโ€ฆ Natural History of Acquired and Inherited Bone Marrow Failure Syndromes NCT05012111n/a1 site๐Ÿ“ Bethesda National Heart, Lung, and Blood Institute (NHLBI) A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) NCT01351545n/a142 sites๐Ÿ“ Birmingham๐Ÿ“ Gilbert๐Ÿ“ Phoenix Center for International Blood and Marrow Transplant Researโ€ฆ ยท Tests: A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias NCT03653338Phase 1, Phase 21 site๐Ÿ“ Pittsburgh Paul Szabolcs ยท Tests: CD3/CD19 depleted leukocytes, CD45RA depleted leukocytes, Hydroxyurea, Rituximab, Alemtuzumab Umbilical Cord Blood-Supported Haplo-HSCT for Aplastic Anemia Treatment Study NCT06650553NA1 site๐Ÿ“ Taiyuan Shanxi Bethune Hospital ยท Tests: Clinically diagnosed AA patients are divided into HLA-matched HSCT group and umbilical cord blood-supported haplo-HSCT โ€ฆ Reduced Dose of Cyclophosphamide Combined With Standard Immunosuppressive Therapy to Treat Severe Aplastic Anemia NCT06695741Phase 21 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: Reduced dose of cyclophosphamide combined with standard immunosuppressive therapy Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms NCT06303193Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: pacritinib Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC NCT02356653EARLY Phase 11 site๐Ÿ“ Philadelphia Children's Hospital of Philadelphia ยท Tests: Transplant of stem cells with CD3+/CD19+ depletion (CliniMACs) Diagnosis and Phenotype Characterisation Using Genomics in Patients With Inherited Bone Marrow Failure (IBMDx Study) NCT05196789n/a1 site๐Ÿ“ Melbourne Peter MacCallum Cancer Centre, Australia ยท Tests: whole genome and transcriptome sequencing Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders NCT03128996Phase 1, Phase 24 sites๐Ÿ“ New Haven๐Ÿ“ Wilmington๐Ÿ“ Grand Rapids Washington University School of Medicine ยท Tests: RIC regimen, GVHD prophylaxis regimen Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders NCT04644016Phase 21 site๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: Clofarabine, Fludarabine, Busulfan, Cyclosporine-A, Mycophenolate Mofetil Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform NCT06999954n/a1 site๐Ÿ“ Woburn Shwachman-Diamond Syndrome Alliance Inc Phase I/II Study of Anti-CD38 Monoclonal Antibody in Refractory Severe Aplastic Anemia NCT07714512Phase 1, Phase 21 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: Isatuximab Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome NCT01624805Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, Methylprednisolone, Pegfilgrastim Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors NCT05194397Phase 23 sites๐Ÿ“ Duarte๐Ÿ“ Philadelphia๐Ÿ“ Memphis Children's Hospital of Philadelphia ยท Tests: Nicotinamide Riboside, Placebo, Exercise Intervention Mobilization of CD34+ Peripheral Blood Stem Cells in Patients With Diamond Blackfan Anemia Syndrome (DBAS) NCT07186179n/a1 site๐Ÿ“ New Hyde Park Northwell Health ยท Tests: Mobilization Regimen Clinical Study on Modified Allogeneic Hematopoietic Stem Cell Transplantation Regimen for Severe Aplastic Anemia NCT06378060Phase 21 site๐Ÿ“ Kunming Hematology department of the 920th hospital ยท Tests: Modified transplantation system A Novel Conditioning Regimen for Haplo-HSCT in Older Patients With SAA NCT07586735n/a1 site๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: BFCA conditiong regimen CD7 CAR-T Cell Sequential Allo-HSCT for Non-malignant Blood and Immune System Diseases NCT06787560EARLY Phase 11 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: CD7 CAR-T cells injection, Allo-HSCT Familial Investigations of Childhood Cancer Predisposition NCT03050268n/a1 site๐Ÿ“ Memphis St. Jude Children's Research Hospital Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) NCT06648096Phase 1, Phase 22 sites๐Ÿ“ Hanover๐Ÿ“ Barcelona Fundaciรณ Institut de Recerca de l'Hospital de la Santa Creuโ€ฆ ยท Tests: Afatinib Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia NCT06517641Phase 225 sites๐Ÿ“ Birmingham๐Ÿ“ Duarte๐Ÿ“ Los Angeles Medical College of Wisconsin ยท Tests: Haploidentical donor bone marrow transplant, Unrelated donor bone marrow transplant
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