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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Brain Tumor, Recurrent

Sonodynamic Therapy in Patients With Recurrent GBM NCT06039709Phase 11 site📍 Charlottesville Shayan Moosa, MD · Tests: 5-ALA and Low-Intensity Focused Ultrasound (SDT) Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial NCT06818331Phase 21 site📍 China The Third Affiliated hospital of Zhejiang Chinese Medical U… · Tests: SMES+PTX, Paclitaxel, Specific mode electroacupuncture stimulation Study of How Safe and Effective Tarlatamab is in Brain Cancers NCT06776250Phase 21 site📍 Toronto University Health Network, Toronto · Tests: Tarlatamab Acute Ischemic Stroke in Patients With Active Cancer NCT07819526n/a1 site📍 Suita Osaka University Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain Metastases NCT05911230NA1 site📍 Basel University Hospital, Basel, Switzerland · Tests: Advanced diffusion-weighted MRI (ADW-MRI) Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) NCT04427384n/a54 sites📍 Phoenix📍 Little Rock📍 Castro Valley GT Medical Technologies, Inc. · Tests: GammaTile Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR BeaM) NCT07053033Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Surgery, LITT A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases NCT07268053EARLY Phase 11 site📍 Phoenix Nader Sanai · Tests: Risvutatug rezetecan Combination Therapy for the Treatment of Diffuse Midline Gliomas NCT05009992Phase 232 sites📍 Birmingham📍 Los Angeles📍 San Diego University of California, San Francisco · Tests: ONC201, Radiation Therapy, Paxalisib, DNX-2401 GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma NCT06815432Phase 11 site📍 Houston Baylor College of Medicine · Tests: 15.GPC3-CAR T cells Early [18F]-FDG PET Dynamic Analysis in Brain Metastases After Radiotherapy. NCT07632092n/a1 site📍 Amiens Centre Hospitalier Universitaire, Amiens · Tests: CT scan Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis NCT07339085NA1 site📍 Los Angeles Jonsson Comprehensive Cancer Center · Tests: Advanced Magnetic Resonance Imaging, Biospecimen Collection, Magnetic Resonance Imaging NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… · Tests: LMP744, Conventional Surgery or Biopsy Chronic CED of TPT for Recurrent Malignant Glioma NCT06666712Phase 11 site📍 New York Jeffrey N. Bruce · Tests: Topotecan Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells NCT04254419Phase 11 site📍 Columbus Nationwide Children's Hospital · Tests: NK cells Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma NCT07506239NA1 site📍 San Francisco University of California, San Francisco · Tests: Laser Interstitial Thermal Therapy (LITT), Magnetic resonance imaging (MRI), Questionnaires A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent Glioblastoma NCT07297212Phase 26 sites📍 Beijing📍 Chongqing📍 Jinan BioNTech SE · Tests: Pumitamig, Bevacizumab, Temozolomide Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors NCT04185038Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors NCT02754544NA1 site📍 Houston M.D. Anderson Cancer Center · Tests: Direct Electrocortical Stimulation, Electrocorticography A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma NCT06552260EARLY Phase 13 sites📍 Boston📍 Boston📍 Boston Ugonma Chukwueke · Tests: Troriluzole Study of Letrozole in Recurrent Gliomas NCT03122197EARLY Phase 11 site📍 Cincinnati University of Cincinnati · Tests: Letrozole Oral Tablet, Temozolomide Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling NCT05857969Phase 11 site📍 Miami Florida International University · Tests: Functional Precision Medicine A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… Surgical Resection of Latent Brain Tumors Prior to Recurrence NCT04810871NA1 site📍 Rochester Mayo Clinic · Tests: Brain Surgery Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites📍 Sioux Falls📍 Sydney Sanford Health ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients NCT06254326Phase 11 site📍 Gainesville University of Florida · Tests: TTRNA-DC vaccines with GM-CSF, Autologous Hematopoietic Stem cells (HSCs), TTRNA-xALT, Td vaccine A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies. NCT07017816EARLY Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: SGT-53, hypofractionated radiotherapy with immunotherapy, Nivolumab A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma NCT07428616Phase 220 sites📍 Birmingham📍 Phoenix📍 San Francisco Exelixis · Tests: Zanzalintinib Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment NCT05432804Phase 1, Phase 239 sites📍 Phoenix📍 Duarte📍 Irvine National Cancer Institute (NCI) · Tests: Biospecimen Collection, Magnetic Resonance Imaging, Placebo Administration, Selinexor, Temozolomide
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