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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for CAR T-cell Therapy

Novel CD19/BCMA Dual-Targeted CAR-T Cell Therapy for the Treatment of Relapsed/Refractory Multiple Myeloma NCT07359014NA1 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Dual CD19/BCMA CAR-T Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia NCT05281809Phase 21 site๐Ÿ“ Pittsburgh John Lister ยท Tests: Chimeric Antigen Receptor (CAR) T-Cell Product (Autologous) GB-5267 for the Treatment Platinum-Resistant Ovarian, Peritoneal, or Fallopian Tube Cancer NCT07489287Phase 11 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: GB-5267 - IV only, GB-5267 -Combined IV and IP Infusion Clinical Study on the EBV CAR-T /TCR-T Cells in the Treatment of Nasopharyngeal Carcinoma NCT05587543EARLY Phase 11 site๐Ÿ“ Shanghai Fudan University ยท Tests: PK Blood Collection, CAR, TCR CD180 CART for Relapsed or Refractory CD180 Positive Hematologic Malignancies NCT07106749Phase 11 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: CD180 CART Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies NCT07284433Phase 1, Phase 213 sites๐Ÿ“ Chicago๐Ÿ“ Evanston๐Ÿ“ Providence AvenCell Therapeutics, Inc. ยท Tests: Cyclophosphamide (Non-IMP, Lymphodepletion), Fludarabine (Non-IMP, Lymphodepletion), Allo-QuadCAR01-T Donor Derived CD117 CAR-T Cells in the Treatment of R/R Acute Myeloid Leukemia NCT07144020EARLY Phase 11 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: CD117 CAR T-cells The Safety and Efficacy of Allogeneic CD70 CAR-T Therapy in Unresectable or Metastatic Clear Cell Renal Cell Carcinoma NCT07645690EARLY Phase 13 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Chinese PLA General Hospital ยท Tests: CLEAR CAR-T cell injection Intrathecal Cytarabine and Hydrocortisone for the Early Treatment of ICANS in Patients Undergoing CAR T Therapy for Non Hodgkin Lymphoma NCT07763210Phase 21 site๐Ÿ“ Nashville Vanderbilt-Ingram Cancer Center ยท Tests: Therapeutic Hydrocortisone, Cytarabine, Dexamethasone, Methylprednisolone, Cyclophosphamide CAR-T Therapy for Refractory Autoimmune Diseases NCT07059169NA1 site๐Ÿ“ Wuhan LiangZou ยท Tests: JY231 (JY231 injection) Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL NCT06481228NA1 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: CAR-T cells, Venetoclax, Olverembatinib GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFฮฒ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers NCT03198052Phase 12 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: CAR-T cells targeting GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFฮฒ, HER2, Lewis-Y, AXL, or EGFR IVIG for Infection Prevention After CAR-T-Cell Therapy NCT05952804Phase 27 sites๐Ÿ“ Duarte๐Ÿ“ Miami๐Ÿ“ Tampa Fred Hutchinson Cancer Center ยท Tests: Immune Globulin Infusion (Human), 10% Solution, Anti-CD19 CAR T Cells Preparation, Saline, Biospecimen Collection, Survโ€ฆ Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rฮฑ2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas NCT07544992Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Echocardiography Test, FDGโ€ฆ Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe Trial NCT07227571Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: FH FOLR1 ST CAR T-cells, Leukapheresis, Fludarabine, Cyclophosphamide, Echocardiography Test A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases. NCT07203404EARLY Phase 11 site๐Ÿ“ Shanghai Nanjing Bioheng Biotech Co., Ltd. ยท Tests: RD06-05 CART Cell Injection A Multicenter Study of CAR-T Cells in Primary Ph+All NCT07252336Phase 21 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: CD19 CAR-T cells A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis NCT06138132Phase 11 site๐Ÿ“ Palo Alto Stanford University ยท Tests: KYV-101 anti-CD19 CAR-T cell therapy, Standard lymphodepletion regimen A Clinical Study of Dual-Target, Universal CAR-T Cell Therapy for Refractory Systemic Lupus Erythematosus NCT07444307Phase 13 sites๐Ÿ“ Hefei๐Ÿ“ Wuhan๐Ÿ“ Beijing Hangzhou Qihan Biotech Co., Ltd. ยท Tests: QT-019B Cell Injection CAR T-cell Therapy Targeting CD19 and BCMA in Patients with AIHA Who Have Failed โ‰ฅ3 Lines of Therapy. NCT06733610Phase 11 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: universal allogeneic anti-CD19/BCMA CAR T-cells Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer NCT06530303Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: Tumor Infiltrating Lymphocytes (TIL), Cyclophosphamide, Fludarabine, Interleukin-2, Pembrolizumab Intracranial Genetically Modified Immune Cells (TGFฮฒR2KO/IL13Rฮฑ2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma NCT06815029Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biospecimen Collection, Chimeric Antigen Receptor T-Cell Therapy, Echocardiography, Fludeoxyglucose F-18, Intracranial โ€ฆ Autologous and Donor-derived CD7 CAR-T Therapy in Refractory or Relapsed T-cell Malignancies NCT06316427Phase 1, Phase 24 sites๐Ÿ“ Beijing๐Ÿ“ Shanghai๐Ÿ“ Shanghai Beijing GoBroad Hospital ยท Tests: Autologous CD7 CAR T-cell, Prior-HSCT donor-derived CD7 CAR T-cell, New donor-derived CD7 CAR T-cell Study of Ultra-Fast CD19 CAR-T Therapy for Refractory SLE NCT07233642Phase 11 site๐Ÿ“ Hangzhou The Children's Hospital of Zhejiang University School of Meโ€ฆ ยท Tests: CD19 CAR-T cells Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy NCT05757219Phase 21 site๐Ÿ“ Tampa H. Lee Moffitt Cancer Center and Research Institute ยท Tests: Itacitinib, Chimeric antigen receptor (CAR) T-cell therapy Intracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/Mem T-lymphocytes) for the Treatment of Central Nervous System Lymphoma NCT05625594Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Aspiration, Biospecimen Collection, Catheterization, CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem T-lymphocytes, Computโ€ฆ CAR-T Cells Therapy for Patients With Autoimmune Diseases NCT07052565NA1 site๐Ÿ“ Hefei Anhui Provincial Hospital ยท Tests: Anti-BCMA and CD19 CART cells will be injected intravenously on a one-time basis Phase IIa Trial of Anti-CD19 CAR T-Cells in Systemic Sclerosis Resistant to Immunosuppressive Therapy NCT07493395Phase 24 sites๐Ÿ“ Lille๐Ÿ“ Montpellier๐Ÿ“ Paris University Hospital, Montpellier ยท Tests: CD19 CAR T Arm A Study of Ultra-fraction Radiotherapy Bridging CART in R/R DLBCL NCT05514327NA1 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: ultra-fraction radiotherapy Feasibility and Safety of Collecting and Combining Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy in Subjects With Relapsed/Refractory Hematological Malignancies NCT05887167Phase 11 site๐Ÿ“ Los Angeles Joshua Sasine, MD, PhD ยท Tests: autologous hematopoietic stem cells added to planned CAR T
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