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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

26 recruiting trials

for Cancer Predisposition Syndrome

Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency NCT06090669Phase 11 site📍 Bethesda National Cancer Institute (NCI) · Tests: TruSight Oncology, imatinib DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study NCT01247597n/a2 sites📍 Bethesda📍 Rockville National Cancer Institute (NCI) Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants NCT07019155n/a1 site📍 Bethesda National Cancer Institute (NCI) Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform NCT06999954n/a1 site📍 Woburn Shwachman-Diamond Syndrome Alliance Inc InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer NCT05463796n/a1 site📍 Boston Dana-Farber Cancer Institute · Tests: Samples Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome NCT04792463n/a1 site📍 Columbus Mohamed Abdel-Rahman Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Population: The INFORM Study NCT06450171NA1 site📍 Boston Dana-Farber Cancer Institute · Tests: GRAIL Galleri Test Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer NCT04903782n/a3 sites📍 Newcastle📍 Sydney📍 Sydney Sydney Children's Hospitals Network · Tests: Family-based whole genome sequencing Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight NCT01238250n/a2 sites📍 Boston📍 Lewisburg Simons Searchlight Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions NCT03160274n/a1 site📍 San Antonio The University of Texas Health Science Center at San Antonio · Tests: Genetic screening Familial Investigations of Childhood Cancer Predisposition NCT03050268n/a1 site📍 Memphis St. Jude Children's Research Hospital Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer NCT00033137n/a1 site📍 Bethesda National Cancer Institute (NCI) Quantitative Susceptibility Biomarker and Brain Structural Property for Cerebral Cavernous Malformation Related Epilepsy NCT04076449n/a2 sites📍 Beijing📍 Beijing yuanli Zhao Study of Families With an Hemopathies Predisposition Related to the DDX41 Gene. NCT06022016NA5 sites📍 Bordeaux📍 Limoges📍 Marseille Institut Claudius Regaud · Tests: For each person (index case or related) included in this study: Questionnaire on Congenital Cancer Signs Through Self-Assessment NCT07378423NA1 site📍 Bern Insel Gruppe AG, University Hospital Bern · Tests: Pre-Visit Preparation (PVP) Brochure, QUOCCAS Questionnaire, Germline genetic sequencing for Cancer Predisposition Synd… Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma NCT05960773Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: Decitabine/cedazuridine Prostate Cancer Genetic Risk Evaluation and Screening Study NCT05129605n/a1 site📍 Boston Massachusetts General Hospital · Tests: Prostate cancer screening Genome-based Management of Patients in Precision Medicine (Ge-Med) Towards a Genomic Health Program NCT04760522NA1 site📍 Tübingen University Hospital Tuebingen · Tests: WGS Diagnostic: Blood take for genetic diagnostic Cancer in Inherited Bone Marrow Failure Syndromes NCT00027274n/a2 sites📍 Bethesda📍 Rockville National Cancer Institute (NCI) Video Capsule Examination in Patients With Lynch Syndrome NCT06712095NA1 site📍 London Royal Marsden NHS Foundation Trust · Tests: Video capsule investigation Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer NCT06888388n/a16 sites📍 New Haven📍 Boston📍 New York Sir Mortimer B. Davis - Jewish General Hospital · Tests: Nipple Sparing Mastectomy (NSM), Skin-Sparing Mastectomy (SSM), Total (Simple) Mastectomy Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome NCT04431024n/a1 site📍 Bethesda National Cancer Institute (NCI) Shwachman Diamond Syndrome Registry and Study NCT06056908n/a4 sites📍 Aurora📍 Boston📍 Boston Boston Children's Hospital Diagnostic Value of Exome/ Genome Sequencing, Conventional Methods in Rare Diseases and Familial Tumor Syndromes NCT04731857n/a1 site📍 Tübingen University Hospital Tuebingen · Tests: Retrospective data analysis Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations NCT02705846n/a1 site📍 Sutton Institute of Cancer Research, United Kingdom · Tests: Observation of treatment outcomes via Questionnaire Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis NCT01441089n/a1 site📍 Bethesda National Cancer Institute (NCI)
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