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30 recruiting trials

for Castration-Sensitive Prostate Carcinoma

PROCARE - PROstate Cancer Real World Evidence Registry NCT06835218n/a53 sites๐Ÿ“ Freiburg im Breisgau๐Ÿ“ Heidelberg๐Ÿ“ Mannheim UroTrials Company (GmbH) Apa/Enza-short Study: Shorter Treatment With Androgen Receptor Pathway Inhibitor in Patients With Low-volume Metastatic Castration-sensitive Prostate Cancer NCT07260435Phase 326 sites๐Ÿ“ Alkmaar๐Ÿ“ Amersfoort๐Ÿ“ Amsterdam Nick Beije ยท Tests: ADT plus only 12 months of ARPI, ADT plus continued ARPI Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response NCT06592924Phase 3395 sites๐Ÿ“ Anchorage๐Ÿ“ Anchorage๐Ÿ“ Anchorage Canadian Cancer Trials Group ยท Tests: Abiraterone, Enzalutamide, Apalutamide, Darolutamide (BAY 1841788), Docetaxel A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer NCT07005154Phase 254 sites๐Ÿ“ Huntsville๐Ÿ“ San Diego๐Ÿ“ Tampa Astellas Pharma Global Development, Inc. ยท Tests: ASP5541, Prednisone, Prednisolone, abiraterone acetate, Adrenocorticotropic hormone Estrogen to Improve Quality of Life for Men With Newly Diagnosed or Recurrent Metastatic Hormone Sensitive Prostate Cancer, EQUIP Trial NCT07466498Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Androgen Receptor Pathway Inhibitor, Transdermal Estrogen, Bone Scan, Computed Tomography, Dual X-ray Absorptiometry PSMA PET-Staged Comprehensive Progression-Directed Radiotherapy for Limited Progression in Prostate Cancer NCT07691697n/a1 site๐Ÿ“ Zamoล›ฤ‡ Affidea Nu-med Center of Oncological DIagnostics and Therapy ยท Tests: Comprehensive Progression-Directed Radiotherapy A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer NCT04729114Phase 125 sites๐Ÿ“ Tucson๐Ÿ“ Anaheim๐Ÿ“ Santa Rosa Astellas Pharma Global Development, Inc. ยท Tests: PRL-02 injection, prednisone, dexamethasone, enzalutamide Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial NCT06931340Phase 3213 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Dublin Alliance for Clinical Trials in Oncology ยท Tests: Androgen Therapy, Apalutamide, Docetaxel, Computed Tomography, Magnetic Resonance Imaging Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial NCT07650240Phase 21 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Abiraterone Acetate, Biospecimen Collection, Leuprolide Acetate, Lutetium Lu 177 Vipivotide Tetraxetan, Prednisone A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors NCT05914116Phase 1, Phase 2107 sites๐Ÿ“ Tucson๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles DualityBio Inc. ยท Tests: DB-1311, Lopinavir and Ritonavir Tablets, itraconazole, Enzalutamide, Abiraterone PSA Biochemical Response as Prognostic Factor in Metastatic Castration-Sensitive Prostate Cancer NCT06652607n/a1 site๐Ÿ“ Rome Fondazione Policlinico Universitario Agostino Gemelli IRCCS ยท Tests: Enzalutamide, Apalutamide (Erleadaโ„ข) 60 mg or 240 mg tablets, Darolutamide (Nubeqaยฎ) 300 mg tablets, Taxotere (docetaxeโ€ฆ A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy NCT06044025Phase 11 site๐Ÿ“ Little Rock University of Arkansas ยท Tests: Metformin, Turmeric ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate Cancer NCT03903835Phase 332 sites๐Ÿ“ Aalst๐Ÿ“ Antwerp๐Ÿ“ Bruges Karolinska Institutet ยท Tests: Enzalutamide Oral Capsule, Abiraterone Oral Tablet, Carboplatin, Cabazitaxel 60 mg Solution for Injection, Docetaxel Inโ€ฆ Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial NCT06378866Phase 23 sites๐Ÿ“ Phoenix๐Ÿ“ Jacksonville๐Ÿ“ Rochester Mayo Clinic ยท Tests: Abiraterone, Apalutamide, Biospecimen Collection, Bone Scan, Computed Tomography A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer NCT05818683Phase 115 sites๐Ÿ“ Sarasota๐Ÿ“ Grand Rapids๐Ÿ“ St Louis Janssen Research & Development, LLC ยท Tests: Pasritamig, Cetrelimab, Cabazitaxel, Docetaxel, Apalutamide An Observational Study to Learn More About the Safety of Darolutamide in Men With Prostate Cancer in Korea NCT06334120n/a1 site๐Ÿ“ Multiple Locations Bayer ยท Tests: Darolutamide (Nubeqa, BAY1841788) Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer NCT04734730Phase 21 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Abiraterone Acetate, Bicalutamide, Degarelix, Goserelin Acetate, Leuprolide Acetate This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naรฏve. NCT07028853Phase 3319 sites๐Ÿ“ Huntsville๐Ÿ“ Huntsville๐Ÿ“ Chandler Pfizer ยท Tests: Mevrometostat, Placebo, Enzalutamide START-MET HS Prostate Cancer. : SbrT & Androgen Receptor Therapy METastatic HSPC NCT05209243NA2 sites๐Ÿ“ Madrid๐Ÿ“ Valencia Instituto de Investigaciรณn en Oncologรญa Radioterรกpica - Funโ€ฆ ยท Tests: SBRT, STANDARD OF CARE Real-world Use of Lutetium (177Lu) Vipivotide Tetraxetan in China(PSMAreal CN) NCT07290270n/a1 site๐Ÿ“ Shanghai Novartis Pharmaceuticals Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer NCT04489719n/a4 sites๐Ÿ“ Baltimore๐Ÿ“ Bozeman๐Ÿ“ Seattle University of Washington ยท Tests: Biospecimen Collection, Questionnaire Administration, Radium Ra 223 Dichloride Efficacy and Safety of Organoid-Based Drug Sensitivity Screening to Guide the Treatment of mCRPC Patients Progressed After First-line Treatment NCT06529549n/a1 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Organoid-Based Drug Sensitivity Screening Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer NCT05997615Phase 124 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ Orange Astellas Pharma Global Development, Inc. ยท Tests: VIR-5500, Androgen receptor signaling inhibitor (ARSI), Docetaxel Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy NCT05919329Phase 41 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Piflufolastat, PSMA PET/CT Scan, PSMA PET/MRI scan, Biospecimen Collection, Electronic Health Record Review A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer NCT04633252Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: PDS01ADC, Docetaxel, M7824, Prednisone, ADT A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1) NCT07723248Phase 312 sites๐Ÿ“ Coral Springs๐Ÿ“ Jeffersonville๐Ÿ“ Holland ORIC Pharmaceuticals ยท Tests: Rinzimetostat, Darolutamide, Enzalutamide, Docetaxel JUR-003 in Adult Patients With Metastatic Prostate Cancer NCT07824349Phase 14 sites๐Ÿ“ Grand Rapids๐Ÿ“ Lake Success๐Ÿ“ Nashville Juri Biosciences, Inc. ยท Tests: JUR-003 Study of Recurrence-directed Therapy (RDT) With or Without Androgen-Deprivation Therapy (ADT) In Patients With Radio-recurrent Oligo-metastatic Hormone/Castrate Sensitive Prostate Cancer (romCSPC) NCT06654336Phase 25 sites๐Ÿ“ Hamilton๐Ÿ“ Ottawa๐Ÿ“ Toronto Ontario Clinical Oncology Group (OCOG) ยท Tests: Recurrence-directed therapy (RDT), ELIGARD 22.5mg FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial NCT06244004Phase 26 sites๐Ÿ“ Chicago๐Ÿ“ DeKalb๐Ÿ“ Geneva Northwestern University ยท Tests: Antiandrogen Therapy, Bone Scan, Computed Tomography, Cytotoxic Chemotherapy, FDG-Positron Emission Tomography Talazoparib Plus Enzalutamide After Progression to Prior ARPi in Metastatic Prostate Cancer NCT06582628Phase 219 sites๐Ÿ“ Bordeaux๐Ÿ“ Brest๐Ÿ“ Lille Fundacion Oncosur ยท Tests: Enzalutamide capsule, Enzalutamide capsule and Talazoparib capsule
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