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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Cellular Immunotherapy, Adoptive

N-803 in Patients With Progressive Synovial Sarcoma and Myxoid/Round Cell Liposarcoma Previously Treated With Adoptive Cellular Therapy NCT07261657EARLY Phase 11 site๐Ÿ“ Chicago Seth Pollack ยท Tests: Biospecimen Collection, Computed Tomography, Leukapheresis, Magnetic Resonance Imaging, Nogapendekin Alfa Inbakicept Dual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCC NCT07500220Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-G3B7-NK dual-target CAR-NK cells, Fludarabine, Cyclophosphamide Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL) NCT07572136Phase 11 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: TSLPR-CART, Cyclophosphamide, Fludarabine CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia NCT07328503Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: CD22 CAR-transduced T cells, Cyclophosphamide, Fludarabine A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1) NCT06557265Phase 1, Phase 219 sites๐Ÿ“ Little Rock๐Ÿ“ Tustin๐Ÿ“ Gainesville Nkarta, Inc. ยท Tests: NKX019, Fludarabine, Cyclophosphamide A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV) NCT04422912Phase 1, Phase 213 sites๐Ÿ“ Redwood City๐Ÿ“ Sacramento๐Ÿ“ New Haven Cabaletta Bio ยท Tests: DSG3-CAART, CABA-201 Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies NCT06904066Phase 11 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: aldesleukin, cyclophosphamide, fludarabine phosphate, Individual Patient TCR-Transduced PBL, TruSight Oncology (TSO) 500 A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2) NCT06733935Phase 1, Phase 218 sites๐Ÿ“ Orange๐Ÿ“ Gainesville๐Ÿ“ Miami Nkarta, Inc. ยท Tests: NKX019, Fludarabine, Cyclophosphamide HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant NCT03326921Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: CD8+ and CD4+ Donor Memory T-cells-expressing HA1-Specific TCR, Bone Marrow Aspiration, Biospecimen Collection Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma. NCT05727904Phase 382 sites๐Ÿ“ Birmingham๐Ÿ“ Duarte๐Ÿ“ Los Angeles Iovance Biotherapeutics, Inc. ยท Tests: Lifileucel plus Pembrolizumab, Pembrolizumab with Optional Crossover Period Autologous huMNC2-CAR44 or huMNC2-CAR22 T Cells for Breast Cancer Targeting Cleaved Form of MUC1 (MUC1*) NCT04020575Phase 11 site๐Ÿ“ Duarte Minerva Biotechnologies Corporation ยท Tests: huMNC2-CAR44 CAR T cells or huMNC2-CAR22 CAR T cells, huMNC2-CAR44 CAR T cells or huMNC2-CAR22 CAR T cells @ RP2D CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies NCT05442515Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: CD19/CD22-CAR-transduced T cells, cyclophosphamide, fludarabine Dual-Targeting CAR-NK Cells in Biomarker-Selected Advanced Colorectal Cancer NCT07589517Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-DUO-CAR-NK-CEA/GCC, Lymphodepletion Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors NCT07443020Phase 11 site๐Ÿ“ Pittsburgh Allegheny Singer Research Institute (also known as Alleghenโ€ฆ ยท Tests: locally manufactured adoptive cellular therapy (ACT) product, Interleukin-2 (IL-2) Long-Term Follow up of Patients Undergoing Hematopoietic Stem Cell Transplantation, Cellular Therapy, or Gene Therapy NCT03000244n/a1 site๐Ÿ“ Bethesda National Cancer Institute (NCI) Target-Selected CAR-NK Cells (CD30, CD5, or Mesothelin) for Relapsed/Refractory B2 Thymoma or Thymic Carcinoma NCT07598955Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: Cyclophosphamide, Fludarabine, EB-CAR30-NK, EB-CAR5-NK, EB-CARMSLN-NK Dual-Target CAR-NK Cells Targeting MSLN, EGFR, or HER2 in Advanced NSCLC NCT07641023Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: Dual-target CAR-NK cells, Lymphodepleting chemotherapy, Supportive care Multi-center Study of TBI-1301 (INN: Mipetresgene Autoleucel; Mip-cel) in Patients With NY-ESO-1 Positive Synovial Sarcoma NCT07174427Phase 33 sites๐Ÿ“ Osaka๐Ÿ“ Fukuoka๐Ÿ“ Kashiwa Takara Bio Inc. ยท Tests: TBI-1301, Cyclophosphamide, Fludarabine Safely Delivered Targeted High-dose Irradiation Followed by Adoptive Immunotherapy with Regulatory and Conventional T Cells to Increase Potency of Hematopoietic Stem Cell Transplantation in High-risk Acute Leukemia NCT06845592NA1 site๐Ÿ“ Perugia University Of Perugia ยท Tests: total marrow/lymphoid irradiation Dual-Target CAR-NK Cells in Recurrent or Refractory Epithelial Ovarian Cancer NCT07589543Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-DUALNK, Cyclophosphamide, Fludarabine Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL NCT05963217Phase 11 site๐Ÿ“ Toronto University Health Network, Toronto ยท Tests: TBI-2001, Cyclophosphamide, Fludarabine ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients NCT06254326Phase 11 site๐Ÿ“ Gainesville University of Florida ยท Tests: TTRNA-DC vaccines with GM-CSF, Autologous Hematopoietic Stem cells (HSCs), TTRNA-xALT, Td vaccine A Multi-Institution Study of TGFฮฒ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue NCT05634369Phase 1, Phase 222 sites๐Ÿ“ South Birmingham๐Ÿ“ Phoenix๐Ÿ“ Little Rock Nationwide Children's Hospital ยท Tests: GEM/DOX + TGFBi expanded NK cells Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG NCT06221553Phase 11 site๐Ÿ“ Bangkok Chulalongkorn University ยท Tests: B7H3 specific CAR T cell with IL-7Ra signaling domain Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer NCT03412877Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Cyclophosphamide, Fludarabine, Aldesleukin, Individual Patient TCR-Transduced PBL, Pembrolizumab (KEYTRUDA(R)) R-MVST Cells for Treatment of Viral Infections NCT05183490Phase 11 site๐Ÿ“ New York Columbia University ยท Tests: Rapidly generated virus specific T (R-MVST) cells A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies NCT06045910Phase 1, Phase 27 sites๐Ÿ“ Birmingham๐Ÿ“ Cambridge๐Ÿ“ Leeds Cancer Research UK ยท Tests: ALETA-001 Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy NCT05646576NA1 site๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: Palliative Care, Usual Care T Cell Therapy of Opportunistic Cytomegalovirus Infection NCT02982902EARLY Phase 11 site๐Ÿ“ Cleveland Mari Dallas ยท Tests: CMV specific adoptive t-cells A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab NCT02621021Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: young TIL, Pembrolizumab, Aldesleukin, Fludarabine, Cyclophosphamide
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