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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Colorectal Cancer Metastatic

Standard Systemic Therapy Combined With High/Low-dose Radiotherapy Plus Toripalimab for Metastatic Colorectal Cancer NCT06525428Phase 21 site📍 Shanghai Fudan University · Tests: standard systemic therapy combined with high/low-dose radiotherapy plus toripalimab DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer NCT06275958Phase 336 sites📍 's-Hertogenbosch📍 Alkmaar📍 Amstelveen Leiden University Medical Center · Tests: Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)… The Safety, Efficacy, and Immune Response of Multimodal Thermal Therapy in the Treatment of Malignant Liver Tumors NCT07159048NA1 site📍 Shanghai Fudan University · Tests: Multimodal Tumor Thermal Therapy System, Radiofrequency Ablation System or Microwave Ablation System Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery NCT06349590Phase 1, Phase 21 site📍 Chicago University of Chicago · Tests: High-fiber/low-fat meals Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors NCT04222413Phase 12 sites📍 Fairway📍 Bethesda National Cancer Institute (NCI) · Tests: Metarrestin Sacituzumab Govitecan in Metastatic Colorectal Cancer NCT06243393Phase 2, Phase 31 site📍 Heidelberg University Hospital Heidelberg · Tests: Sacituzumab Govitecan (SG), Physicians Choice (PhC). Efficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer NCT06008119Phase 31 site📍 Beijing Shanghai Kechow Pharma, Inc. · Tests: Tunlametinib plus Vemurafenib, Doublets Chemotherapy ± Bevacizumab or Doublets Chemotherapy ± Cetuximab A Comparative Study of Pharmacokinetics, Safety, and Immunogenicity of RPH-030 and Vectibix® in Patients With Metastatic Colorectal Cancer With Wild-type RAS as First-line Therapy in Combination With FOLFIRI NCT07543744Phase 126 sites📍 Arkhangelsk📍 Istra📍 Ivanovo R-Pharm · Tests: RPH-030, Vectibix®, Irinotecan, Calcium Folinate, Fluorouracil CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site📍 Chicago Northwestern University · Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride ROMANCE: "Irinotecan Plus Cetuximab Rechallenge Versus Trifluridine/Tipiracil Plus Bevacizumab in Molecularly Selected Metastatic Colorectal Cancer" NCT07381764Phase 226 sites📍 Alessandria📍 Ancona📍 Aviano Gruppo Oncologico Italia Meridionale · Tests: Erbitux (Cetuximab), Bevacizumab, Irinotecan, Trifluridine/tipiracil Prospective Validation of an AI Model for Predicting Liver Metastasis in Colorectal Cancer NCT07392567n/a1 site📍 Wuhan Tongji Hospital · Tests: Multimodal Deep Learning Prediction Model Novel Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer NCT07759921NA1 site📍 Aurora University of Colorado, Denver · Tests: Couple-based Mindfulness Intervention, Health and Wellness Education Control Condition Evaluation of a Diagnostic Test to Identify the Best Drugs for Treatment of Metastatic Colorectal Cancer NCT07171554NA1 site📍 Lørenskog Oncosyne AS · Tests: µCAN drug screen test, Standard-of-Care Therapy Explore Biomarkers Associated With Prognosis of Recurrent and Metastatic CRC After Surgery by Multi-omics Methods NCT05501353n/a1 site📍 Hangzhou Second Affiliated Hospital, Zhejiang University, School of … · Tests: no intervention A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer NCT07284849Phase 3293 sites📍 Mobile📍 Tucson📍 Tucson Incyte Corporation · Tests: INCA33890, Placebo, Bevacizumab, FOLFOX Evaluation of Irinotecan Liposome (II) Combined With 5-FU, LV, and Bevacizumab for mCRC NCT06643793Phase 21 site📍 Nanjing Affiliated Hospital of Nantong University · Tests: Irinotecan liposome (ll) + 5-FU/LV + bevacizumab Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers NCT06580574Phase 21 site📍 Beijing Peking University · Tests: PD1/PDL1 antibody monotherapy, up to 24 weeks, Intensive immunotherapy plus anti-VEGF treatment, up to 24 weeks, Radica… Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis NCT07193862EARLY Phase 12 sites📍 Lake Success📍 New Hyde Park Northwell Health · Tests: Doxorubicin, FOLFOX, Botensilimab, Balstilimab, Bevacizumab, FOLFIRI, FOLFIRINOX, AGEN2373 A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors NCT07318805Phase 113 sites📍 Duarte📍 Grand Rapids📍 Long Island City Pfizer · Tests: PF-08032562, Fulvestrant, Cetuximab, Fluorouracil, Oxaliplatin Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR ) Combined With Anti-PD1，Chemotherapy and Target Therapy for Metastatic Colorectal Cancer NCT06841159Phase 21 site📍 Shanghai Fudan University · Tests: Ultra-fractionated radiation therapy, Sintilimab, Standard systemic therapy Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer NCT06530303Phase 1, Phase 21 site📍 Beijing Essen Biotech · Tests: Tumor Infiltrating Lymphocytes (TIL), Cyclophosphamide, Fludarabine, Interleukin-2, Pembrolizumab A Randomized, Double-blind, Placebo-controlled, Parallel-group, Comparative, Phase III Study to Evaluate the Efficacy and Safety of Nuvastatic® 300mg Capsule in Reducing Cancer-Tumor in Patients With Metastatic Colorectal Cancer Receiving Standard Chemotherapy. NCT07669454Phase 36 sites📍 Visakhapatnam📍 Mysore📍 Jalgaon Natureceuticals Sdn Bhd · Tests: Nuvastatic 300, Placebo JS212 Combination Therapies in Metastatic Colorectal Cancer NCT07503756Phase 21 site📍 Shanghai Shanghai Junshi Bioscience Co., Ltd. · Tests: JS212, Capecitabine, Bevacizumab, Oxaliplatin, JS207 Selective Internal Radiation Therapy With 90Y Resin Micropheres for Refractory Colorectal Cancer Liver Metastases NCT04491929n/a1 site📍 Aarhus N Aarhus University Hospital Liver Transplantation for Non-resectable Colorectal Liver Metastases: Translational Research NCT05398380NA1 site📍 Barcelona Hospital Vall d'Hebron · Tests: Liver transplantation An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response NCT04796818NA1 site📍 Houston M.D. Anderson Cancer Center · Tests: Diffusion Weighted Imaging AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors NCT07094113Phase 139 sites📍 Duarte📍 Los Angeles📍 Atlanta Amgen · Tests: AMG 410, Pembrolizumab, Panitumumab Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection NCT06698146n/a1 site📍 Chicago Northwestern University The Safety and Efficacy of Cetuximab Beta Plus Fruquintinib With or Without Immune Checkpoint Inhibitorrs in First-line Treatment of RAS/BRAF Wild Type Unresectable Metastatic Colorectal Cancer NCT07257653Phase 21 site📍 Hangzhou Zhejiang University · Tests: Cetuximab β；Fruquintinib；, Cetuximab β；Fruquintinib；anti-PD1 antibody；, Cetuximab β；Fruquintinib；anti-PD1/CTLA4 antibody The Phase 1b/IIa, Open-label, Dose Escalation and Dose Expansion to Evaluate Safety, Tolerability, and Preliminary Efficacy of the Combination of HCB101, Cetuximab/Bevacizumab, and FOLFOX/FOLFIRI in Advanced or Metastatic Colorectal Cancer NCT07204574Phase 1, Phase 21 site📍 Taoyuan Chang Gung Memorial Hospital · Tests: HCB101, Bevacizumab, Cetuximab (Erbitux), FOLFIRI (Fluorouracil (5-FU), leucovorin, irinotecan), FOLFOX (Oxaliplatin/Le…
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