🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

23 recruiting trials

for DIPG

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site📍 Boadilla del Monte Fundación de investigación HM · Tests: Olaparib; 177Lu-DOTATATE Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma NCT01106794n/a1 site📍 Washington D.C. Children's National Research Institute NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity Focused Ultrasound With Microbubbles in Combination With T-Cell Infusion in Patients With Newly Diagnosed Diffuse Midline Glioma (LIFT) NCT07796061Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: TAA-T Cell, BBB Disruption xPedite: A Study to Expedite DIPG and DMG Research NCT06140719n/a1 site📍 Los Altos xCures Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors NCT04185038Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults NCT06305910Phase 11 site📍 Minneapolis OX2 Therapeutics · Tests: Treatment with CD200AR-L C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B) NCT04099797Phase 11 site📍 Houston Baylor College of Medicine · Tests: C7R-GD2.CART cells (IV and ICV infusion), C7R-GD2.CART cells (IV and ICV infusion) A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma NCT04250064Phase 21 site📍 Mumbai Tata Memorial Centre · Tests: Bevacizumab Injection, Ultra-low-dose RT Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG NCT06221553Phase 11 site📍 Bangkok Chulalongkorn University · Tests: B7H3 specific CAR T cell with IL-7Ra signaling domain Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0 NCT05476939Phase 356 sites📍 Brussels📍 Leuven📍 Aarhus Gustave Roussy, Cancer Campus, Grand Paris · Tests: Everolimus, ONC201, Radiotherapy Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant NCT05843253Phase 220 sites📍 Aurora📍 Washington D.C.📍 Chicago Nationwide Children's Hospital · Tests: Ribociclib, Everolimus, Temozolomide (TMZ) ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas NCT06838676Phase 220 sites📍 Aurora📍 Washington D.C.📍 Miami Nationwide Children's Hospital · Tests: ACT001 Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation NCT07076498Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: M032 rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG NCT04943848Phase 13 sites📍 Orange📍 Chicago📍 Boston Ann & Robert H Lurie Children's Hospital of Chicago · Tests: rHSC-DIPGVax, Balstilimab, Zalifrelimab Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas NCT06465199Phase 1, Phase 214 sites📍 Birmingham📍 Little Rock📍 Hartford Milton S. Hershey Medical Center · Tests: Eflornithine (DFMO), AMXT 1501 Dicaprate FUS Etoposide for DMG NCT05762419Phase 11 site📍 New York Columbia University · Tests: Etoposide; Oral, 50 Mg, Focused ultrasound with neuro-navigator-controlled sonication GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG) NCT04196413Phase 11 site📍 Stanford Stanford University · Tests: GD2 CAR T cells, Fludarabine, Cyclophosphamide, Rituximab PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma NCT05096481Phase 213 sites📍 Aurora📍 Washington D.C.📍 Miami Nationwide Children's Hospital · Tests: PEP-CMV, Temozolomide, Tetanus Diphtheria Vaccine International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository NCT03101813n/a1 site📍 Cincinnati Children's Hospital Medical Center, Cincinnati Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age NCT05956821Phase 1, Phase 21 site📍 Miami University of Miami · Tests: SIACI of cetuximab and bevacizumab Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). NCT07680439Phase 26 sites📍 Los Angeles📍 Atlanta📍 Chicago BrainChild Bio, Inc · Tests: BCB-276 Study of Olutasidenib and Temozolomide in HGG NCT06161974Phase 220 sites📍 Aurora📍 Washington D.C.📍 Miami Rigel Pharmaceuticals · Tests: Olutasidenib + TMZ
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy