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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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15 recruiting trials

for DMG

CAR T Cells to Target GD2 for DMG NCT05544526Phase 11 site📍 London University College, London · Tests: GD2 CAR T cells ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors NCT04732065Phase 17 sites📍 San Francisco📍 Washington D.C.📍 Atlanta Sabine Mueller, MD, PhD · Tests: ONC206, Standard of Care Radiation Therapy, Optional Proton (1H) MR spectroscopy (MRS) NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity Focused Ultrasound With Microbubbles in Combination With T-Cell Infusion in Patients With Newly Diagnosed Diffuse Midline Glioma (LIFT) NCT07796061Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: TAA-T Cell, BBB Disruption xPedite: A Study to Expedite DIPG and DMG Research NCT06140719n/a1 site📍 Los Altos xCures Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors NCT04185038Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults NCT06305910Phase 11 site📍 Minneapolis OX2 Therapeutics · Tests: Treatment with CD200AR-L ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) NCT05580562Phase 3162 sites📍 Phoenix📍 Phoenix📍 Phoenix Jazz Pharmaceuticals · Tests: Dordaviprone (ONC201), Dordaviprone (ONC201) + Placebo, Placebo Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites📍 Sioux Falls📍 Sydney Sanford Health Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation NCT07076498Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: M032 rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG NCT04943848Phase 13 sites📍 Orange📍 Chicago📍 Boston Ann & Robert H Lurie Children's Hospital of Chicago · Tests: rHSC-DIPGVax, Balstilimab, Zalifrelimab FUS Etoposide for DMG NCT05762419Phase 11 site📍 New York Columbia University · Tests: Etoposide; Oral, 50 Mg, Focused ultrasound with neuro-navigator-controlled sonication GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG) NCT04196413Phase 11 site📍 Stanford Stanford University · Tests: GD2 CAR T cells, Fludarabine, Cyclophosphamide, Rituximab International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository NCT03101813n/a1 site📍 Cincinnati Children's Hospital Medical Center, Cincinnati Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). NCT07680439Phase 26 sites📍 Los Angeles📍 Atlanta📍 Chicago BrainChild Bio, Inc · Tests: BCB-276
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