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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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24 recruiting trials

for Dementia, Early Onset

Lecanemab for Early Onset Familial Alzheimer's Disease NCT06883019n/a15 sites📍 Beijing📍 Guangdong📍 Guizhou RenJi Hospital A Study of Donanemab, RG6289, or the Combination of Donanemab and RG6289 in Presenilin 1 (PSEN1) E280A Mutation Carriers for the Treatment of Autosomal-Dominant Alzheimer's Disease NCT06996730Phase 2, Phase 31 site📍 Medellín Banner Health · Tests: Donanemab, RG6289, Donanemab placebo, RG6289 placebo Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease NCT06688968NA3 sites📍 Montpellier📍 Montpellier📍 Montpellier University Hospital, Montpellier · Tests: neuropsychologist interview, questionnaire GnRH Therapy on Cognition in Down Syndrome NCT04390646Phase 2, Phase 31 site📍 Lausanne Nelly Pitteloud · Tests: GnRH, gonadorelin acetate, 0.9% NaCl A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation NCT06647498Phase 2, Phase 337 sites📍 Birmingham📍 La Jolla📍 Los Angeles Washington University School of Medicine · Tests: Remternetug, Matching Placebo (Remternetug) Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites📍 Sioux Falls📍 Sydney Sanford Health Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study NCT05573490NA1 site📍 Indianapolis Indiana University · Tests: Cognitive Training, Tai Chi- Qi Gong, Brain Games, Stretching Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD) NCT01353430n/a1 site📍 Irvine University of California, Irvine Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy NCT05655195NA1 site📍 Cambridge Massachusetts Institute of Technology · Tests: GENUS device (Active Settings), GENUS device (sham settings) A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer's Disease NCT07328451Phase 14 sites📍 's-Hertogenbosch📍 Amsterdam📍 Zwolle Denali Therapeutics Inc. · Tests: DNL628, Placebo A Multifocal tDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia NCT06668610NA1 site📍 Caserta University of Campania Luigi Vanvitelli · Tests: StarStim 32, Neuroelectrics, Spain - Real multifocal tDCS, StarStim 32, Neuroelectrics, Spain - Sham multifocal tDCS, C… Donepezil Versus Non-drug Treatment in Alzheimer's Disease. NCT04661280Phase 31 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Donepezil MIMA Pilot Study: MIcrostructure of the Medial Temporal Lobe in Early Alzheimer's Disease NCT06099587NA1 site📍 Rennes Rennes University Hospital · Tests: high-resolution diffusion MRI A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD NCT05231785Phase 18 sites📍 La Jolla📍 Indianapolis📍 Montreal Alnylam Pharmaceuticals · Tests: ALN-APP, Placebo Genetic Studies of Early-onset Dementia NCT04906863n/a1 site📍 New York Columbia University · Tests: Blood draw, Neurocognitive testing, Medical questionnaire MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY NCT04150198NA2 sites📍 Orsay📍 Paris Institut National de la Santé Et de la Recherche Médicale, … · Tests: TEP/IRM Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease NCT07221344Phase 1, Phase 24 sites📍 East York📍 Toronto📍 Montreal Arrowhead Pharmaceuticals · Tests: ARO-MAPT-SC, Placebo Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study NCT02740634NA1 site📍 Rochester Mayo Clinic · Tests: F-18 AV 1451, C-11 PiB Transcranial Magnetic Stimulation to Slow Down Cognitive Decline in Alzheimer's Disease NCT07036328NA1 site📍 Amsterdam Willem de Haan · Tests: repetitive transcranial magnetic stimulation, sham repetitive transcranial magnetic stimulation The Dampness Syndrome of Chinese Medicine Cohort Study NCT05315895n/a1 site📍 Guangzhou Guangzhou University of Traditional Chinese Medicine · Tests: natural aging process Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia NCT06584357n/a26 sites📍 Atlantis📍 Aventura📍 Clermont GAP Innovations, PBC · Tests: Biomarker Data Collection, MK6240 Network-based biOmarker Discovery of Neurodegenerative Diseases Using Multimodal Connectivity NCT06080659NA1 site📍 Rennes Rennes University Hospital · Tests: fMRI, CONFMEM A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation NCT05552157Phase 2, Phase 337 sites📍 Birmingham📍 La Jolla📍 Los Angeles Washington University School of Medicine · Tests: Remternetug (SC), Matching Placebo (Remternetug) NYSCF Scientific Discovery Biobank NCT06203106n/a1 site📍 New York New York Stem Cell Foundation Research Institute · Tests: Biological Sample Collection
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