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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for ESCC

Adebrelimab ยฑInduction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC NCT06510660Phase 21 site๐Ÿ“ Fuzhou Fujian Medical University Union Hospital ยท Tests: adebrelimab Adebrelimab Combined With Neoadjuvant Chemoradiotherapy for Esophageal Squamous Cell Carcinoma NCT07595770Phase 21 site๐Ÿ“ Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ยท Tests: โ€ข Adebrelimab and nab-paclitaxel, carboplatin in Combination With radiotherapy A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies NCT05473156Phase 1, Phase 21 site๐Ÿ“ Taipei AP Biosciences Inc. ยท Tests: AP203, AP203 Individualized Tumor-Informed CtDNA Analysis for Monitoring Postoperative Recurrence in ESCC (NEOCRTEC2401) NCT06561178n/a1 site๐Ÿ“ Guangzhou Sun Yat-Sen University Cancer Center ยท Tests: molecular residual disease detection Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC (KEYSTONE-002) NCT04807673Phase 31 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Pembrolizumab, Paclitaxel, Cisplatin, neoadjuvant chemoradiotherapy A Study of Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell Carcinoma NCT06354530Phase 2, Phase 31 site๐Ÿ“ Chongqing Army Medical Center of PLA ยท Tests: anlotinib, Thoracic radiotherapy Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC NCT06601309Phase 21 site๐Ÿ“ Fuzhou Fujian Medical University Union Hospital ยท Tests: Serplulimab, Paclitaxel+Cisplatin (Neoadjuvant Chemotherapy), Paclitaxel+Cisplatin(Concurrent Chemoradiotherapy), Radioโ€ฆ A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC NCT07385001Phase 1, Phase 21 site๐Ÿ“ Xi'an Tang-Du Hospital ยท Tests: AK112, AK112, AK112 + Neoadjuvant chemotherapy A Clinical Study of Sintilimab as Adjuvant Therapy in Node-positive ESCC NCT06190639Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: sintilimab Benmelstobart Combined With Radiochemotherapy as Neoadjuvant Treatment Iin ESCC NCT06637163Phase 25 sites๐Ÿ“ Shantou๐Ÿ“ Shenyang๐Ÿ“ Shanghai Shanghai Zhongshan Hospital ยท Tests: Benmelstobart+ Paclitaxel + Carboplatin+ Radiotherapy, Paclitaxel + Carboplatin + Radiotherapy A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS) NCT06709417Phase 21 site๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: Sintilimab, Chemotherapy, radiotherapy A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types NCT07503808Phase 115 sites๐Ÿ“ Denver๐Ÿ“ Sarasota๐Ÿ“ Detroit IDEAYA Biosciences ยท Tests: IDE034 Phase II Study Evaluating Safety and Efficacy of Tislelizumab for Elderly Patients Unfit for Chemotherapy, With Advanced Esophageal Squamous-cell Carcinoma NCT07205731Phase 230 sites๐Ÿ“ Annecy๐Ÿ“ Amiens๐Ÿ“ Avignon University Hospital, Clermont-Ferrand ยท Tests: Tislelizumab is a fully humanized monoclonal antibody specific for human PD-1 Adebrelimab Combined With Neoadjuvant Chemotherapy in Borderline Resectable Locally Advanced Esophageal Squamous Cell Carcinoma NCT07638436Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Adebrelimab Injection KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy for First-line Advanced Esophageal Cancer NCT07481058Phase 21 site๐Ÿ“ Beijing Beijing Konruns Pharmaceutical Co., Ltd. ยท Tests: KC1036, Toripalimab, Paclitaxel, Cisplatin, KC1036 A Randomized Controlled Trial Evaluating of Prophylactic Irradiation in CRT for cT1bN0M0 ESCC NCT04328948Phase 31 site๐Ÿ“ Tokyo National Cancer Center, Japan ยท Tests: Chemoradiotherapy Chemoradiation Plus Iparomlimab Consolidation in Older With ESCC NCT07038629Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: S1, Iparomlimab, Radiation A Phase II Study of Anlotinib + PD-1 Inhibitor vs. PD-1 Inhibitor Maintenance After First-Line Chemoimmunotherapy in Advanced ESCC (Esophageal Squamous Cell Carcinoma) NCT07863141Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: anlotinib + PD-1 inhibitor, PD-1 inhibitor Time-of-Day of Immunotherapy Infusion in Neoadjuvant Immunochemotherapy for Thoracic ESCC NCT07452601Phase 21 site๐Ÿ“ Xi'an Tang-Du Hospital ยท Tests: Adebrelimab plus nab-paclitaxel and cisplatin A Study of Perioperative Camrelizumab Combined With Chemotherapy in Patients With Resectable ESCC NCT05182944Phase 21 site๐Ÿ“ Zhengzhou The First Affiliated Hospital of Zhengzhou University ยท Tests: A๏ผšnon-pCR patients, B๏ผšnon-pCR patients, A๏ผšpCR patients, B๏ผšpCR patients A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCC NCT07733180Phase 24 sites๐Ÿ“ Yokohama๐Ÿ“ Takatsukishi๐Ÿ“ ChuoKu BeOne Medicines ยท Tests: Tislelizumab, Oxaliplatin, Leucovorin, 5-fluorouracil (5-FU) A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors NCT04686682Phase 1, Phase 21 site๐Ÿ“ Tianjin Jacobio Pharmaceuticals Co., Ltd. ยท Tests: JAB-8263, JAB-8263 A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors NCT05914116Phase 1, Phase 2107 sites๐Ÿ“ Tucson๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles DualityBio Inc. ยท Tests: DB-1311, Lopinavir and Ritonavir Tablets, itraconazole, Enzalutamide, Abiraterone PPIO-008 Tislelizumab Combined With S-1 in Patients With ypT+N0 ESCC After Radical Resection With Neoadjuvant STUDY NCT06354140Phase 21 site๐Ÿ“ Chongqing Daping Hospital and the Research Institute of Surgery of thโ€ฆ ยท Tests: Tegafur AK112 Combined With Chemotherapy as the First-line Treatment in Advanced Esophageal Squamous Cell Carcinoma Patients NCT06489197Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Ivonescimab combined with albumin paclitaxel and cisplatin A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors NCT07887971Phase 11 site๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-2519 (therapeutic), [64Cu]Cu-AKY-2519 (imaging) Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma NCT06675201Phase 21 site๐Ÿ“ Chengdu Sichuan University ยท Tests: neoantigen-loaded dendritic cell vaccine (NeoDC-Vac) Neoadjuvant Immunotherapy Plus CRT Versus Neoadjuvant CRT for Locally Advanced Resectable ESCC NCT04973306Phase 2, Phase 31 site๐Ÿ“ Shanghai Shanghai Zhongshan Hospital ยท Tests: Neoadjuvant Chemoradiotherapy, Tislelizumab, Ivor-Lewis or Mckeown Esophagectomy(Mckeown Esophagectomy recommended) dCRT vs. Surgery in Resectable ESCC Patients Achieving cCR/PR After Induction Chemoimmunotherapy NCT07162506Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Surgery, Radiotherapy, Chemotherapy, Immunotherapy Becotatug Vedotin ยฑ Anti-PD-1 in Pretreated Advanced ESCC NCT07403136Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Vebrekotuzumab, PD-1 antibody
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