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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Esophageal Squamous Cell Carcinoma Stage II

Efficacy and Safety of Concurrent PD-1 Inhibitor and Radiotherapy With Immunonutrition for Esophageal Squamous Cell Carcinoma NCT06342167Phase 210 sites๐Ÿ“ Beijing๐Ÿ“ Fujian๐Ÿ“ Handan Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Radiotherapy, Programmed Cell Death Protein 1 Inhibitor, Immunonutrition support Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer NCT06173986Phase 1, Phase 21 site๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: PD-1inhibitor, nab-paclitaxel + cisplatin, Radiotherapy Nimotuzumab Combined With Sintilimab and Chemotherapy for Advanced Esophageal Squamous Cell Carcinoma NCT06718205Phase 21 site๐Ÿ“ Zhengzhou The First Affiliated Hospital of Zhengzhou University ยท Tests: Nimotuzumab, Sintilimab, Paclitaxel-albumin, Cisplatin A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer NCT05563766Phase 27 sites๐Ÿ“ Palo Alto๐Ÿ“ Ann Arbor๐Ÿ“ Durham VA Office of Research and Development ยท Tests: Itraconazole Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC NCT06601309Phase 21 site๐Ÿ“ Fuzhou Fujian Medical University Union Hospital ยท Tests: Serplulimab, Paclitaxel+Cisplatin (Neoadjuvant Chemotherapy), Paclitaxel+Cisplatin(Concurrent Chemoradiotherapy), Radioโ€ฆ Neoadjuvant Comprehensive Treatment for Unresectable Esophageal Cancer NCT06430658Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Tislelizumab (BGB-A317) with chemoradiotherapy A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC NCT07385001Phase 1, Phase 21 site๐Ÿ“ Xi'an Tang-Du Hospital ยท Tests: AK112, AK112, AK112 + Neoadjuvant chemotherapy Perioperative Tislelizumab Plus Chemotherapy for Resectable Thoracic Oesophageal Squamous Cell Carcinoma NCT06056336Phase 21 site๐Ÿ“ Shanghai Guo Xufeng ยท Tests: Tislelizumab RAPA-201 Therapy of Solid Tumors NCT05144698Phase 1, Phase 21 site๐Ÿ“ Hackensack Rapa Therapeutics LLC ยท Tests: RAPA-201 Rapamycin Resistant T Cells, Chemotherapy Prior to RAPA-201 Therapy, Pembrolizumab (PD-1 Blocking Antibody) A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS) NCT06709417Phase 21 site๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: Sintilimab, Chemotherapy, radiotherapy Phase II Study Evaluating Safety and Efficacy of Tislelizumab for Elderly Patients Unfit for Chemotherapy, With Advanced Esophageal Squamous-cell Carcinoma NCT07205731Phase 230 sites๐Ÿ“ Annecy๐Ÿ“ Amiens๐Ÿ“ Avignon University Hospital, Clermont-Ferrand ยท Tests: Tislelizumab is a fully humanized monoclonal antibody specific for human PD-1 Adebrelimab Combined With Neoadjuvant Chemotherapy in Borderline Resectable Locally Advanced Esophageal Squamous Cell Carcinoma NCT07638436Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Adebrelimab Injection Radiotherapy Combined With Immunochemotherapy in Metastatic Esophageal Squamous Cell Carcinoma NCT05978193Phase 22 sites๐Ÿ“ Shanghai๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: LDRT+CFRT, Immunotherapy, Chemotherapy KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy for First-line Advanced Esophageal Cancer NCT07481058Phase 21 site๐Ÿ“ Beijing Beijing Konruns Pharmaceutical Co., Ltd. ยท Tests: KC1036, Toripalimab, Paclitaxel, Cisplatin, KC1036 Pembrolizumab Combined With Preoperative Chemotherapy (Albumin Paclitaxel+Carboplatin) Neoadjuvant Therapy for Resectable Locally Advanced (Stage II/III) Esophageal Squamous Cell Carcinoma NCT06304350Phase 21 site๐Ÿ“ Shanghai Tongji University ยท Tests: Combination of pembrolizumab and platinum containing dual drugs Chemoradiation Plus Iparomlimab Consolidation in Older With ESCC NCT07038629Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: S1, Iparomlimab, Radiation A Phase II Study of Anlotinib + PD-1 Inhibitor vs. PD-1 Inhibitor Maintenance After First-Line Chemoimmunotherapy in Advanced ESCC (Esophageal Squamous Cell Carcinoma) NCT07863141Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: anlotinib + PD-1 inhibitor, PD-1 inhibitor A Study of Perioperative Camrelizumab Combined With Chemotherapy in Patients With Resectable ESCC NCT05182944Phase 21 site๐Ÿ“ Zhengzhou The First Affiliated Hospital of Zhengzhou University ยท Tests: A๏ผšnon-pCR patients, B๏ผšnon-pCR patients, A๏ผšpCR patients, B๏ผšpCR patients Consolidation of Toripalimab After Chemoradiotherapy in Elderly Esophageal Cancer (EC-CRT-007) NCT06187597Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: S-1, Toripalimab, Intensity-modulated radiotherapy PPIO-008 Tislelizumab Combined With S-1 in Patients With ypT+N0 ESCC After Radical Resection With Neoadjuvant STUDY NCT06354140Phase 21 site๐Ÿ“ Chongqing Daping Hospital and the Research Institute of Surgery of thโ€ฆ ยท Tests: Tegafur AK112 Combined With Chemotherapy as the First-line Treatment in Advanced Esophageal Squamous Cell Carcinoma Patients NCT06489197Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Ivonescimab combined with albumin paclitaxel and cisplatin Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers NCT04221893NA2 sites๐Ÿ“ San Francisco๐Ÿ“ Walnut Creek University of California, San Francisco ยท Tests: Radiation Therapy (RT) Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma NCT06675201Phase 21 site๐Ÿ“ Chengdu Sichuan University ยท Tests: neoantigen-loaded dendritic cell vaccine (NeoDC-Vac) Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma in the Era of Immunotherapy NCT06272214Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: Adjuvant radiotherapy, Observation Neoadjuvant Immunotherapy Plus CRT Versus Neoadjuvant CRT for Locally Advanced Resectable ESCC NCT04973306Phase 2, Phase 31 site๐Ÿ“ Shanghai Shanghai Zhongshan Hospital ยท Tests: Neoadjuvant Chemoradiotherapy, Tislelizumab, Ivor-Lewis or Mckeown Esophagectomy(Mckeown Esophagectomy recommended) A Study of MT-4561 in Patients With Various Advanced Solid Tumors NCT06943521Phase 1, Phase 26 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ Columbus Tanabe Pharma America, Inc. ยท Tests: MT-4561 dCRT vs. Surgery in Resectable ESCC Patients Achieving cCR/PR After Induction Chemoimmunotherapy NCT07162506Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Surgery, Radiotherapy, Chemotherapy, Immunotherapy Study of Dalpiciclib Isethionate Plus Pyrotinib Maleate in the Treatment of Advanced Esophageal Squamous Cell Carcinoma NCT06684600Phase 21 site๐Ÿ“ Beijing Peking University ยท Tests: Dalpiciclib + Pyrotinib Becotatug Vedotin ยฑ Anti-PD-1 in Pretreated Advanced ESCC NCT07403136Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Vebrekotuzumab, PD-1 antibody Perioperative Cadonilimab Combined With Neoadjuvant Chemotherapy in Resectable Esophageal Squamous Cell Carcinoma (ESCC) NCT07263919Phase 21 site๐Ÿ“ Xi'an Akeso ยท Tests: Cadonilimab (AK104), Cisplatin, Paclitaxel
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