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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Extensive Stage Lung Small Cell Carcinoma

Irinotecan Liposome (II) or Etoposide Combined With Adebrelimab and Carboplatin in the Treatment of ES-SCLC NCT06739928Phase 21 site๐Ÿ“ Guangzhou Guangzhou Institute of Respiratory Disease ยท Tests: Irinotecan liposome (II) combined with adebrelimab and carboplatin, etoposide combined with adebrelimab and carboplatin Small Extracellular Vesicle miRNAs as Predictive Biomarkers for Immunochemotherapy Efficacy in Extensive-stage Small Cell Lung Cancer NCT07070011n/a1 site๐Ÿ“ Shanghai Shanghai Chest Hospital of Shanghai Jiao Tong University ยท Tests: EC/EP + ICIs A Prospective, Single-Arm, Single-Center Phase II Study Evaluating the Efficacy and Safety of Chidamide Combined With PD-L1 Inhibitor, Carboplatin, and Etoposide as First-Line Treatment in Patients With Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) NCT07373964Phase 21 site๐Ÿ“ Shenyang China Medical University, China ยท Tests: Chidamide Tablets๏ผ› PD-L1 Inhibitor (as per chosen drug's prescribing information)๏ผ›Carboplatin๏ผ› Etoposide A Study of MHB088C Injection Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer NCT06954246Phase 31 site๐Ÿ“ Shanghai Qilu Pharmaceutical Co., Ltd. ยท Tests: MHB088C for Injection, Topotecan, Irinotecan, Paclitaxel A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS). NCT06646276Phase 3183 sites๐Ÿ“ Daphne๐Ÿ“ Hot Springs๐Ÿ“ Fort Myers Bristol-Myers Squibb ยท Tests: BMS-986489 (Atigotatug+Nivolumab), Atezolizumab, Carboplatin, Etoposide WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases NCT06243003Phase 1, Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: HA-WBRT plus SBRT Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer NCT06287775Phase 1, Phase 243 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ La Jolla National Cancer Institute (NCI) ยท Tests: Atezolizumab, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Durvalumab Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer NCT07226999Phase 2, Phase 382 sites๐Ÿ“ Fayetteville๐Ÿ“ Rogers๐Ÿ“ Springdale Pfizer ยท Tests: PF-08634404, Atezolizumab, Chemotherapy A Phase I Study to Evaluate the Safety and Preliminary Efficacy of [225Ac]Ac-DOTATATE Injection Combined With Tislelizumab in the Maintenance Treatment Period for Patients of Extensive-stage Small Cell Lung Cancer (ES-SCLC) With Somatostatin Receptors (SSTR)+ as First-line Treatment NCT07413042Phase 11 site๐Ÿ“ Beijing Peking University Cancer Hospital & Institute ยท Tests: [225Ac]Ac-DOTATATE MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer NCT05903092Phase 24 sites๐Ÿ“ Indianapolis๐Ÿ“ Iowa City๐Ÿ“ Detroit Hirva Mamdani ยท Tests: Durvalumab, Monalizumab, Carboplatin or Cisplatin, Etoposide A Study of Bemotuzumab Plus Chemotherapy and Anlotinib Induction Followed by Bemotuzumab, Anlotinib and Consolidative Thoracic Radiotherapy in Extensive-Stage Small Cell Lung Cancer NCT07358676Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Bemotuzumab + Anlotinib + Chemotherapy + Radiotherapy Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer NCT06712355Phase 3225 sites๐Ÿ“ Tucson๐Ÿ“ Clermont๐Ÿ“ Palm Bay BioNTech SE ยท Tests: Pumitamig, Atezolizumab, Etoposide, Carboplatin (or cisplatin if carboplatin is not tolerated) Pembrolizumab and Olaparib Treatment of Extensive Small Cell Lung Cancer (ES-SCLC) NCT05623319Phase 212 sites๐Ÿ“ Meldola๐Ÿ“ Monza๐Ÿ“ Pesaro Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRโ€ฆ ยท Tests: Pembrolizumab/Olaparib A Study Comparing BL-B01D1 Combined With Tislelizumab Versus Platinum-containing Chemotherapy Combined With Tislelizumab as First-line Treatment in Patients With Extensive-stage Small Cell Lung Cancer(PANKU-Lung07) NCT07502300Phase 32 sites๐Ÿ“ Zhengzhou๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, Tislelizumab, Carboplatin, Etoposide Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM) NCT07139990Phase 11 site๐Ÿ“ Dallas University of Texas Southwestern Medical Center ยท Tests: Cohort A: Extensive Stage Small Cell Lung Cancer (ES-SCLC) Thoracic Tumor PULSAR (Personalized ultrahypofractionated stโ€ฆ Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC). NCT06663098Phase 225 sites๐Ÿ“ Aviano (PN)๐Ÿ“ Bari๐Ÿ“ Bologna Gruppo Oncologico Italiano di Ricerca Clinica ยท Tests: Atezolizumab, Carboplatin, Etoposide NK Cells Plus ICI for SCLC Maintenance NCT07759856Phase 21 site๐Ÿ“ Tianjin Tianjin First Central Hospital ยท Tests: Allogeneic Natural Killer Cells, Immune Checkpoint Inhibitor Second-line Immunotherapy for ES-SCLC NCT06853678NA1 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Adebrelimab, Selinexor, Nab-paclitaxel IN10018 Combination Therapy in Treatment-naรฏve ES-SCLC NCT06030258Phase 1, Phase 23 sites๐Ÿ“ Jinan๐Ÿ“ Tianjin๐Ÿ“ Zhengzhou InxMed (Shanghai) Co., Ltd. ยท Tests: IN10018, Tislelizumab, Carboplatin, Etoposide Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation NCT06110572Phase 1, Phase 21 site๐Ÿ“ Nashville Vanderbilt-Ingram Cancer Center ยท Tests: Carboplatin, Atezolizumab, Etoposide, Total Body Irradiation, Hypofractionated Radiation Therapy A Study to Investigate Treatment Patterns and Effectiveness of Tislelizumab in European Patients With Resectable or Advanced Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC) NCT07652736n/a6 sites๐Ÿ“ Cรณrdoba๐Ÿ“ Jaรฉn๐Ÿ“ Lugo BeOne Medicines ยท Tests: Tislelizumab A Trial of Tarlatamab in Patients With Pretreated Extensive-stage Small Cell Lung Cancer (ES-SCLC) and ECOG PS 2 NCT07203053Phase 219 sites๐Ÿ“ Angers๐Ÿ“ Bordeaux๐Ÿ“ Lyon ETOP IBCSG Partners Foundation ยท Tests: Tarlatamab Molecular Analysis and Treatment Options of SCLC NCT05945745n/a1 site๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: Chemotherapy Phase II Trial of Consolidative Thoracic Radiotherapy for ES-SCLC After Standard Care of Chemo-immunotherapy NCT05552846NA1 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: thoracic radiotherapy DAREON ยฎ -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy NCT07472517Phase 3245 sites๐Ÿ“ Mobile๐Ÿ“ Little Rock๐Ÿ“ Hialeah Boehringer Ingelheim ยท Tests: obrixtamig, atezolizumab, carboplatin, etoposide Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC NCT06217757Phase 1, Phase 21 site๐Ÿ“ Chengdu Sichuan University ยท Tests: Low-dose radiotherapy, Etoposide, Cisplatin, Sugemalimab, Olaparib Palliative Radiotherapy With Lurbinectedin in Patients With Extensive Stage Small Cell Lung Cancer NCT05244239Phase 13 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Lurbinectedin, Palliative Radiation Therapy A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003) NCT07227597Phase 1, Phase 257 sites๐Ÿ“ Santa Rosa๐Ÿ“ Aurora๐Ÿ“ Orlando Merck Sharp & Dohme LLC ยท Tests: Gocatamig, I-DXd, Atezolizumab, Carboplatin, Etoposide A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination Therapy in Participants With Relapsed/Refractory Small Cell Lung Cancer NCT07325136Phase 1, Phase 213 sites๐Ÿ“ Detroit๐Ÿ“ Buffalo๐Ÿ“ Durham Bristol-Myers Squibb ยท Tests: BMS-986525, Pumitamig Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC NCT06536868Phase 26 sites๐Ÿ“ Jincheng๐Ÿ“ Jinzhong๐Ÿ“ Taiyuan Second Hospital of Shanxi Medical University ยท Tests: Tislelizumab, Etoposide, Carboplatin or Cisplatin, Thoracic radiotherapy
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