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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Extensive-stage Small Cell Lung Cancer (ES-SCLC)

Irinotecan Liposome (II) or Etoposide Combined With Adebrelimab and Carboplatin in the Treatment of ES-SCLC NCT06739928Phase 21 site๐Ÿ“ Guangzhou Guangzhou Institute of Respiratory Disease ยท Tests: Irinotecan liposome (II) combined with adebrelimab and carboplatin, etoposide combined with adebrelimab and carboplatin Small Extracellular Vesicle miRNAs as Predictive Biomarkers for Immunochemotherapy Efficacy in Extensive-stage Small Cell Lung Cancer NCT07070011n/a1 site๐Ÿ“ Shanghai Shanghai Chest Hospital of Shanghai Jiao Tong University ยท Tests: EC/EP + ICIs A Prospective, Single-Arm, Single-Center Phase II Study Evaluating the Efficacy and Safety of Chidamide Combined With PD-L1 Inhibitor, Carboplatin, and Etoposide as First-Line Treatment in Patients With Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) NCT07373964Phase 21 site๐Ÿ“ Shenyang China Medical University, China ยท Tests: Chidamide Tablets๏ผ› PD-L1 Inhibitor (as per chosen drug's prescribing information)๏ผ›Carboplatin๏ผ› Etoposide A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS). NCT06646276Phase 3183 sites๐Ÿ“ Daphne๐Ÿ“ Hot Springs๐Ÿ“ Fort Myers Bristol-Myers Squibb ยท Tests: BMS-986489 (Atigotatug+Nivolumab), Atezolizumab, Carboplatin, Etoposide A Phase I Study to Evaluate the Safety and Preliminary Efficacy of [225Ac]Ac-DOTATATE Injection Combined With Tislelizumab in the Maintenance Treatment Period for Patients of Extensive-stage Small Cell Lung Cancer (ES-SCLC) With Somatostatin Receptors (SSTR)+ as First-line Treatment NCT07413042Phase 11 site๐Ÿ“ Beijing Peking University Cancer Hospital & Institute ยท Tests: [225Ac]Ac-DOTATATE Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer NCT06712355Phase 3225 sites๐Ÿ“ Tucson๐Ÿ“ Clermont๐Ÿ“ Palm Bay BioNTech SE ยท Tests: Pumitamig, Atezolizumab, Etoposide, Carboplatin (or cisplatin if carboplatin is not tolerated) Pembrolizumab and Olaparib Treatment of Extensive Small Cell Lung Cancer (ES-SCLC) NCT05623319Phase 212 sites๐Ÿ“ Meldola๐Ÿ“ Monza๐Ÿ“ Pesaro Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRโ€ฆ ยท Tests: Pembrolizumab/Olaparib Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC). NCT06663098Phase 225 sites๐Ÿ“ Aviano (PN)๐Ÿ“ Bari๐Ÿ“ Bologna Gruppo Oncologico Italiano di Ricerca Clinica ยท Tests: Atezolizumab, Carboplatin, Etoposide Second-line Immunotherapy for ES-SCLC NCT06853678NA1 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Adebrelimab, Selinexor, Nab-paclitaxel IN10018 Combination Therapy in Treatment-naรฏve ES-SCLC NCT06030258Phase 1, Phase 23 sites๐Ÿ“ Jinan๐Ÿ“ Tianjin๐Ÿ“ Zhengzhou InxMed (Shanghai) Co., Ltd. ยท Tests: IN10018, Tislelizumab, Carboplatin, Etoposide Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation NCT06110572Phase 1, Phase 21 site๐Ÿ“ Nashville Vanderbilt-Ingram Cancer Center ยท Tests: Carboplatin, Atezolizumab, Etoposide, Total Body Irradiation, Hypofractionated Radiation Therapy A Trial of Tarlatamab in Patients With Pretreated Extensive-stage Small Cell Lung Cancer (ES-SCLC) and ECOG PS 2 NCT07203053Phase 219 sites๐Ÿ“ Angers๐Ÿ“ Bordeaux๐Ÿ“ Lyon ETOP IBCSG Partners Foundation ยท Tests: Tarlatamab Phase II Trial of Consolidative Thoracic Radiotherapy for ES-SCLC After Standard Care of Chemo-immunotherapy NCT05552846NA1 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: thoracic radiotherapy DAREON ยฎ -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy NCT07472517Phase 3245 sites๐Ÿ“ Mobile๐Ÿ“ Little Rock๐Ÿ“ Hialeah Boehringer Ingelheim ยท Tests: obrixtamig, atezolizumab, carboplatin, etoposide Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC NCT06217757Phase 1, Phase 21 site๐Ÿ“ Chengdu Sichuan University ยท Tests: Low-dose radiotherapy, Etoposide, Cisplatin, Sugemalimab, Olaparib A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination Therapy in Participants With Relapsed/Refractory Small Cell Lung Cancer NCT07325136Phase 1, Phase 213 sites๐Ÿ“ Detroit๐Ÿ“ Buffalo๐Ÿ“ Durham Bristol-Myers Squibb ยท Tests: BMS-986525, Pumitamig Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC NCT06536868Phase 26 sites๐Ÿ“ Jincheng๐Ÿ“ Jinzhong๐Ÿ“ Taiyuan Second Hospital of Shanxi Medical University ยท Tests: Tislelizumab, Etoposide, Carboplatin or Cisplatin, Thoracic radiotherapy Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum Based First-line Chemotherapy (ES-SCLC) NCT07778316Phase 39 sites๐Ÿ“ Orlando๐Ÿ“ Grand Rapids๐Ÿ“ Omaha Amgen ยท Tests: Tarlatamab Tislelizumab Combined With Chemotherapy and Relayed Radiotherapy in First-line Treatment of ES-SCLC NCT06838208Phase 21 site๐Ÿ“ Hefei Anhui Provincial Cancer Hospital ยท Tests: Tislelizumab, Carboplatin /Cisplatin, Etoposide Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients NCT05703971Phase 1, Phase 217 sites๐Ÿ“ Lone Tree๐Ÿ“ St Louis๐Ÿ“ Canton Genprex, Inc. ยท Tests: quaratusugene ozeplasmid, atezolizumab Metronomic Oral Paclitaxel Plus PD-1/ PD-L1 Inhibitor Maintenance in Advanced Lung Cancer (PULSE Study) NCT07744698Phase 41 site๐Ÿ“ Hefei Anhui Provincial Cancer Hospital ยท Tests: Paclitaxel Oral Solution, PD-1/PD-L1 inhibitor (eg. Tislelizumab) A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors NCT07887971Phase 11 site๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-2519 (therapeutic), [64Cu]Cu-AKY-2519 (imaging) A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer NCT07155174Phase 269 sites๐Ÿ“ New Haven๐Ÿ“ Gainesville๐Ÿ“ Ocala AbbVie ยท Tests: ABBV-706, Atezolizumab, Etoposide, Carboplatin, Carboplatin Teniposide, Cisplatin and Serplulimab for Treatment of ES-SCLC, a Randomized Controlled Study NCT07583511Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Teniposide, Etoposide, serplulimab, cisplatin Sintilimab Combined With Tafolecimab and Chemotherapy as First-Line Treatment for Extensive-Stage Small Cell Lung Cancer NCT07061535Phase 25 sites๐Ÿ“ Changsha๐Ÿ“ Jinan๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Tafolecimab, Sintilimab (approved), Etoposide, Carboplatin / Cisplatin PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer NCT06429696Phase 21 site๐Ÿ“ Guangzhou Nanfang Hospital, Southern Medical University ยท Tests: PD-L1 inhibitor combined with apatinib First Line Pembrolizumab, Plinabulin Plus Etoposide and Platinum (EP) for ES-SCLC NCT05745350Phase 21 site๐Ÿ“ Wuhan Xiaorong Dong ยท Tests: Pembrolizumab, Plinabulin plus Etoposide and Platinum Adebrelimab Combine With Etoposide Capsules in ES-SCLC Maintenance Therapy NCT07141264Phase 21 site๐Ÿ“ Xi'an Tang-Du Hospital ยท Tests: Adebrelimab combined with Etoposide Capsules Clinical Study on Using TCR to Predict the Effect of Tislelizumab + Chemotherapy in the First-line Treatment of ES-SCLC NCT07244016n/a1 site๐Ÿ“ Zhengzhou Henan Cancer Hospital Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study NCT06769126Phase 2148 sites๐Ÿ“ Loma Linda๐Ÿ“ Rancho Mirage๐Ÿ“ Sacramento SWOG Cancer Research Network ยท Tests: Biospecimen Collection, Ceralasertib, Computed Tomography, Durvalumab, Etoposide
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