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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Gastro-esophageal Junction (GEJ) Cancer

Study of Adjuvant Chemotherapy With or Without PD-1 Inhibitors and Chemoradiotherapy in Resected pN3 Gastric (G) or GEJ Adenocarcinoma NCT04997837Phase 31 site๐Ÿ“ Shanghai Fudan University ยท Tests: PD-1 inhibitor, Oxaliplatin, Capecitabine, Tegafur-gimeracil-oteracil potassium, 5-FU AK104 in Combination With AK112 Plus Chemotherapy(SOX/XELOX) as First-line Treatment for Advanced G/GEJ Cancer NCT06196697Phase 21 site๐Ÿ“ Harbin Harbin Medical University ยท Tests: Cadonilimab, Ivonescimab, XELOX, SOX Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors NCT07660055Phase 15 sites๐Ÿ“ Omaha๐Ÿ“ Darlinghurst๐Ÿ“ Montreal Novartis Pharmaceuticals ยท Tests: [68Ga]Ga-DWJ155, [177Lu]Lu-DWJ155 A Study of Sigvotatug Vedotin in Advanced Solid Tumors NCT04389632Phase 1158 sites๐Ÿ“ Anchorage๐Ÿ“ Fayetteville๐Ÿ“ Rogers Seagen, a wholly owned subsidiary of Pfizer ยท Tests: sigvotatug vedotin, pembrolizumab, cisplatin, carboplatin Fruquintinib Combined With Trastuzumab and XELOX as First-line Treatment in Patients With HER2-positive Advanced Gastric Cancer NCT07334431Phase 1, Phase 21 site๐Ÿ“ Zhengzhou Henan Cancer Hospital ยท Tests: fruquintinib๏ผ‹trastuzumab + XELOX A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors NCT06131840Phase 148 sites๐Ÿ“ Phoenix๐Ÿ“ Scottsdale๐Ÿ“ Duarte Seagen, a wholly owned subsidiary of Pfizer ยท Tests: PF-08046050, bevacizumab, 5-Fluorouracil (5-FU), Oxaliplatin, Leucovorin (LV) M108 Plus CAPOX Versus Placebo Plus CAPOX as First-line Treatment for Claudin (CLDN) 18.2-Positive, HER2-Negative, PD-L1 CPS<5, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma. NCT06177041Phase 31 site๐Ÿ“ Beijing FutureGen Biopharmaceutical (Beijing) Co., Ltd ยท Tests: M108 monoclonal antibody, Placebo, Oxaliplatin, Capecitabine Low-dose Radiotherapy Combined With Chemotherapy and AK112 as Second-line Treatment in Patients With Advanced G/GEJ Cancer NCT06791148Phase 21 site๐Ÿ“ Nanjing The Affiliated Nanjing Drum Tower Hospital of Nanjing Univeโ€ฆ ยท Tests: Low-dose radiotherapy, albumin-bound paclitaxel, AK112 Disitamab Vedotin Plus Trastuzumab in Patients With HER2 Positive GC/GEJ Patiens NCT06572319Phase 1, Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: Disitamab Vedotin(RC48) Plus Tratuzumab Perioperative HLX10 (Serplulimab) With S-1+Oxaliplatin (SOX) in Locally Advanced and PD-L1-Positive Gastric or Esophagogastric Junction Adenocarcinoma NCT07699939Phase 218 sites๐Ÿ“ Chiba๐Ÿ“ Fukuoka๐Ÿ“ Gifu National Cancer Center, Japan ยท Tests: serplulimab, Placebo DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 17 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ St Louis Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 OGT-assisted Overlap Esophagojejunostomy Versus Traditional Overlap Method NCT05450835NA12 sites๐Ÿ“ Quanzhou๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Nanfang Hospital, Southern Medical University ยท Tests: OGT group, Overlap group Neoadjuvant Cadonilimab Combined With Perioperative Oxaliplatin Plus S1 for Diffuse or Mixed Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma NCT06949033Phase 34 sites๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou Zuoyi Jiao ยท Tests: Neoadjuvant cadonilimab combined with perioperative SOX, Neoadjuvant placebo plus perioperative SOX A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer NCT07673887Phase 38 sites๐Ÿ“ Saint Louis Park๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Astellas Pharma Global Development, Inc. ยท Tests: ASP2138, Pembrolizumab, Oxaliplatin, Capecitabine, Folinic acid Phase II Trial of Neoadjuvant Thymalfasin, PD-1 Inhibitor, and Chemoradiotherapy for cStage III GEJ Adenocarcinoma NCT07277439Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: Radiochemoimmunotherapy, Immunomodulation Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma NCT05702229Phase 244 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Baton Rouge AstraZeneca ยท Tests: Rilvegostomig, Volrustomig, FOLFOX, XELOX, AZD0901 Perioperative FLOT(D) With Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR) in Esophageal Cancer NCT07700420Phase 11 site๐Ÿ“ Dallas University of Texas Southwestern Medical Center ยท Tests: PULSAR- Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy, FLOT (Fluorouracil+Leucovorin+Oxaliplatin+Dโ€ฆ Tislelizumab in Combination With Pre-operative CRT Versus SOC for Locally Advanced G/GEJ Adenocarcinoma NCT05687357Phase 23 sites๐Ÿ“ Wuhan๐Ÿ“ Nanjing๐Ÿ“ Taiyuan The Affiliated Nanjing Drum Tower Hospital of Nanjing Univeโ€ฆ ยท Tests: Tislelizumab, S-1, Oxaliplatin, Nab paclitaxel, Radiation A Study of Cadonilimab Combined With Chemotherapy in People With Gastric or Gastroesophageal Junction Cancer NCT07631000Phase 27 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Cadonilimab First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors NCT07284186Phase 110 sites๐Ÿ“ Scottsdale๐Ÿ“ Duarte๐Ÿ“ Orange Plexium, Inc. ยท Tests: PLX-61639 Pan-tumor MRD Study NCT06605404n/a47 sites๐Ÿ“ Birmingham๐Ÿ“ Bullhead City๐Ÿ“ Casa Grande Paradigm Health ยท Tests: blood and tissue samples, blood and tissue samples A Beta-only IL-2 ImmunoTherapY Study NCT05086692Phase 1, Phase 228 sites๐Ÿ“ San Diego๐Ÿ“ San Francisco๐Ÿ“ Santa Monica Medicenna Therapeutics, Inc. ยท Tests: MDNA11, Pembrolizumab (KEYTRUDAยฎ) A Trial of Adebrelimab Plus (SHR-A1811/SHR-A1904 With Chemotherapy) or SHR-8068 as Treatment for Gastric/GEJ Cancer NCT07110571Phase 22 sites๐Ÿ“ Shijiazhuang๐Ÿ“ Hangzhou Suzhou Suncadia Biopharmaceuticals Co., Ltd. ยท Tests: Adebrelimab Injection, SHR-A1811 for Injection, SHR-A1904 for Injection, SHR-8068 Injection Albumin-bound Paclitaxel-based Second-line Treatment Regimens for Locally Advanced or Metastatic G/GEJ Adenocarcinoma NCT07389876n/a1 site๐Ÿ“ Shanghai Fudan University ยท Tests: Albumin-bound Paclitaxel, Immune Checkpoint Inhibitor, Anti-angiogenic drug, Trastuzumab emtansine HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT) NCT04447352Phase 315 sites๐Ÿ“ Aachen๐Ÿ“ Dresden๐Ÿ“ Frankfurt Krankenhaus Nordwest ยท Tests: 5-Fluorouracil, Leucovorin, Oxaliplatin, Docetaxel, Cisplatin An Open Label Phase 2 Study of Total Neoadjuvant Therapy (TNT) Consisting of FLOT With Pembrolizumab and Short Radiation for Patients With Locally Advanced Gastroesophageal Junction Adenocarcinoma NCT07018570Phase 21 site๐Ÿ“ Kashiwa National Cancer Center Hospital East ยท Tests: Pembrolizumab, Docetaxel, Oxaliplatin, Levofolinate, Fluorouracil (5-FU) Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer NCT04592211Phase 1, Phase 21 site๐Ÿ“ Seoul Yonsei University ยท Tests: olaparib+pembrolizumab+paclitaxel A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma NCT07023315Phase 36 sites๐Ÿ“ Beijing๐Ÿ“ Fuzhou๐Ÿ“ Shijiazhuang Akeso ยท Tests: Cadonilimab, SOX chemotherapy, Placebo A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors NCT06657144Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ Duarte๐Ÿ“ Aurora Coherus Oncology, Inc. ยท Tests: CHS-114, Toripalimab, 5 Fluorouracil, Cisplatin A Study of PD-1 Inhibitors Combined With Fruquintinib and Chemotherapy in First-line Treatment of HER2-negative Advanced G/GEJ Cancer NCT06158919NA1 site๐Ÿ“ Shanghai Fudan University ยท Tests: Fruquintinibใ€Nivolumabใ€Sintilimabใ€Oxaliplatinใ€Teysunoใ€Capecitabine
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