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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Gastroesophageal Junction (GEJ) Cancer

Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer NCT06121700Phase 21 site📍 Shanghai Fudan University · Tests: Radiotherapy targeted to the primary lesion, Radiotherapy targeted to the metastatic lesions, Anti-PD-1 monoclonal anti… AK104 in Combination With AK112 Plus Chemotherapy(SOX/XELOX) as First-line Treatment for Advanced G/GEJ Cancer NCT06196697Phase 21 site📍 Harbin Harbin Medical University · Tests: Cadonilimab, Ivonescimab, XELOX, SOX Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer NCT04592211Phase 1, Phase 21 site📍 Seoul Yonsei University · Tests: olaparib+pembrolizumab+paclitaxel A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer. NCT06902545n/a15 sites📍 Goyang-si📍 Suwon📍 Suwon Astellas Pharma Korea, Inc. · Tests: zolbetuximab The Effect of Different Digestive Tract Reconstruction Methods on Postoperative Quality of Life After Proximal Gastrectomy NCT06929949n/a1 site📍 Changchun The First Hospital of Jilin University A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors NCT06131840Phase 148 sites📍 Phoenix📍 Scottsdale📍 Duarte Seagen, a wholly owned subsidiary of Pfizer · Tests: PF-08046050, bevacizumab, 5-Fluorouracil (5-FU), Oxaliplatin, Leucovorin (LV) A Trial of Adebrelimab Plus (SHR-A1811/SHR-A1904 With Chemotherapy) or SHR-8068 as Treatment for Gastric/GEJ Cancer NCT07110571Phase 22 sites📍 Shijiazhuang📍 Hangzhou Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Tests: Adebrelimab Injection, SHR-A1811 for Injection, SHR-A1904 for Injection, SHR-8068 Injection A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors NCT04895709Phase 1, Phase 247 sites📍 Clovis📍 Los Angeles📍 Newport Beach Bristol-Myers Squibb · Tests: BMS-986340, BMS-936558-01, Docetaxel, Pumitamig A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma NCT07023315Phase 36 sites📍 Beijing📍 Fuzhou📍 Shijiazhuang Akeso · Tests: Cadonilimab, SOX chemotherapy, Placebo A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites📍 Duarte📍 Los Angeles📍 San Francisco Nurix Therapeutics, Inc. · Tests: NX-1607, Paclitaxel Cadonilimab Combination Regimen as First-line Treatment for HER2-expressing GC/GEJ Patients NCT06650332Phase 1, Phase 21 site📍 Hangzhou Zhejiang Cancer Hospital · Tests: cadonilimab, Trastuzumab, XELOX, Disitamab Vedotin, mFOLFOX6 Dual-target CLDN18.2/HER2 CAR-NK Cells for Advanced Gastric/GEJ Cancer NCT07551362Phase 1, Phase 21 site📍 Shenzhen Beijing Biotech · Tests: EB-DT-CAR-NK, Fludarabine, Cyclophosphamide Perioperative Treatment of Combined Radiotherapy With SOX, Apatinib and Camrelizumab for Oesophagogastric Cancer NCT07026149Phase 21 site📍 Shanghai Ruijin Hospital · Tests: Apatinib+Camrelizumab+SOX, Preoperative Radiotherapy A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer NCT06901531Phase 3252 sites📍 Birmingham📍 Bakersfield📍 Cerritos Astellas Pharma Global Development, Inc. · Tests: zolbetuximab, Pembrolizumab, Capecitabine, Oxaliplatin, Folinic acid (leucovorin or local equivalent) Perioperative FLOT(D) With Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR) in Esophageal Cancer NCT07700420Phase 11 site📍 Dallas University of Texas Southwestern Medical Center · Tests: PULSAR- Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy, FLOT (Fluorouracil+Leucovorin+Oxaliplatin+D… DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 17 sites📍 Denver📍 Grand Rapids📍 St Louis Duboce Biopharmaceuticals, Inc. · Tests: DBC-664 Study of Adjuvant Chemotherapy With or Without PD-1 Inhibitors and Chemoradiotherapy in Resected pN3 Gastric (G) or GEJ Adenocarcinoma NCT04997837Phase 31 site📍 Shanghai Fudan University · Tests: PD-1 inhibitor, Oxaliplatin, Capecitabine, Tegafur-gimeracil-oteracil potassium, 5-FU Fruquintinib in Combination With Sintilimab and CAPEOX as First-line Treatment for G/GEJ Cancer NCT06329973Phase 1, Phase 21 site📍 Zhengzhou Henan Cancer Hospital · Tests: Fruquintinib in combination with Sintilimab and CAPEOX OGT-assisted Overlap Esophagojejunostomy Versus Traditional Overlap Method NCT05450835NA12 sites📍 Quanzhou📍 Guangzhou📍 Guangzhou Nanfang Hospital, Southern Medical University · Tests: OGT group, Overlap group An Open Label Phase 2 Study of Total Neoadjuvant Therapy (TNT) Consisting of FLOT With Pembrolizumab and Short Radiation for Patients With Locally Advanced Gastroesophageal Junction Adenocarcinoma NCT07018570Phase 21 site📍 Kashiwa National Cancer Center Hospital East · Tests: Pembrolizumab, Docetaxel, Oxaliplatin, Levofolinate, Fluorouracil (5-FU) Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma NCT06925243Phase 34 sites📍 Lanzhou📍 Lanzhou📍 Lanzhou Zuoyi Jiao · Tests: Neoadjuvant apatinib combined with sintilimab and perioperative SOX, Neoadjuvant sintilimab combined with perioperative… A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors NCT06657144Phase 130 sites📍 Tucson📍 Duarte📍 Aurora Coherus Oncology, Inc. · Tests: CHS-114, Toripalimab, 5 Fluorouracil, Cisplatin Tislelizumab in Combination With Pre-operative CRT Versus SOC for Locally Advanced G/GEJ Adenocarcinoma NCT05687357Phase 23 sites📍 Wuhan📍 Nanjing📍 Taiyuan The Affiliated Nanjing Drum Tower Hospital of Nanjing Unive… · Tests: Tislelizumab, S-1, Oxaliplatin, Nab paclitaxel, Radiation T-Dxd in Combination With Ramucirumab as HER2 Low Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma NCT05894824Phase 1, Phase 21 site📍 Seoul Yonsei University · Tests: T-Dxd(Trastuzmab deruxtecan), Ramucirumab Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination With or Without Nivolumab for the 1L Treatment of Participants With HER2-negative, Previously Untreated, Unresectable or Metastatic Gastric/GEJ Adenocarcinoma NCT07700979Phase 325 sites📍 Phoenix📍 Los Angeles📍 Denver Akeso · Tests: Cadonilimab, CAPOX regimen, Nivolumab, Placebo HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT) NCT04447352Phase 315 sites📍 Aachen📍 Dresden📍 Frankfurt Krankenhaus Nordwest · Tests: 5-Fluorouracil, Leucovorin, Oxaliplatin, Docetaxel, Cisplatin Perioperative HLX10 (Serplulimab) With S-1+Oxaliplatin (SOX) in Locally Advanced and PD-L1-Positive Gastric or Esophagogastric Junction Adenocarcinoma NCT07699939Phase 218 sites📍 Chiba📍 Fukuoka📍 Gifu National Cancer Center, Japan · Tests: serplulimab, Placebo A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites📍 Birmingham📍 Los Angeles📍 Miami Astellas Pharma Global Development, Inc. · Tests: ASP546C Neoadjuvant Cadonilimab Combined With Perioperative Oxaliplatin Plus S1 for Diffuse or Mixed Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma NCT06949033Phase 34 sites📍 Lanzhou📍 Lanzhou📍 Lanzhou Zuoyi Jiao · Tests: Neoadjuvant cadonilimab combined with perioperative SOX, Neoadjuvant placebo plus perioperative SOX A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer NCT05365581Phase 146 sites📍 Orange📍 Santa Monica📍 Chicago Astellas Pharma Global Development, Inc. · Tests: ASP2138, Pembrolizumab, Oxaliplatin, Leucovorin, Fluorouracil
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