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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Glioblastoma, IDH-wildtype

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma NCT07452458Phase 354 sites๐Ÿ“ Irvine๐Ÿ“ Los Angeles๐Ÿ“ Orange NRG Oncology ยท Tests: Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Questionnaire Administration, Radiation Therapy Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rฮฑ2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas NCT07544992Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Echocardiography Test, FDGโ€ฆ Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma NCT05879367Phase 18 sites๐Ÿ“ Birmingham๐Ÿ“ Detroit๐Ÿ“ New York Orbus Therapeutics, Inc. ยท Tests: Eflornithine (Dose Level 1), Eflornithine (Dose Level 2), Eflornithine (Dose Level -1), Temozolomide Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas NCT07468136Phase 1, Phase 21 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Eflornithine, Lumbar Puncture, Magnetic Resonance Imaging, Retifanlimab Metabolomics and Transcriptomics of Low- and High-Grade Gliomas NCT07832734n/a1 site๐Ÿ“ Milan I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203) NCT06146738n/a8 sites๐Ÿ“ San Francisco๐Ÿ“ Boston๐Ÿ“ Leuven Jasper Gerritsen ยท Tests: Palliative Care, Tumor biopsy, Tumor resection Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide NCT04945148Phase 27 sites๐Ÿ“ Suresnes๐Ÿ“ Bron๐Ÿ“ Marseille Hopital Foch ยท Tests: Metformin, Radiation IMRT, Temozolomide Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site๐Ÿ“ Bethesda National Institute of Neurological Disorders and Stroke (NIโ€ฆ ยท Tests: LMP744, Conventional Surgery or Biopsy Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma NCT06419946Phase 320 sites๐Ÿ“ Graz๐Ÿ“ Innsbruck๐Ÿ“ Linz Vastra Gotaland Region ยท Tests: Temozolomide, Lomustine A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma NCT06552260EARLY Phase 13 sites๐Ÿ“ Boston๐Ÿ“ Boston๐Ÿ“ Boston Ugonma Chukwueke ยท Tests: Troriluzole THERApeutic Outcomes Related to Gut microBIOME in Glioblastoma (GBM) Patients Receiving Chemo-radiation (THERABIOME-GBM) NCT05326334n/a1 site๐Ÿ“ Ottawa Ottawa Hospital Research Institute Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma NCT06410248Phase 11 site๐Ÿ“ Chicago Northwestern University ยท Tests: Biospecimen Collection, Magnetic Resonance Imaging, Questionnaire Administration, Resection, Temozolomide Feasibility of ONCOhabitats for Surgical and Treatment Planning in IDH-Wildtype Glioblastoma (SINUE) NCT07111195n/a5 sites๐Ÿ“ Alicante๐Ÿ“ Barcelona๐Ÿ“ Murcia Juan M Garcia-Gomez ยท Tests: The ONCOhabitats software for MRI-based habitat segmentation Glutamate Inhibitors in Glioblastoma NCT05664464Phase 1, Phase 21 site๐Ÿ“ Zurich University of Zurich ยท Tests: Gabapentin, Sulfasalazine, Memantine, Temozolomide, Radiotherapy Feasibility of FMISO in Brain Tumors NCT03649880Phase 21 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: ยนโธF-Fluoromisonidazole, Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography, Oxygen Therapy Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment NCT05432804Phase 1, Phase 239 sites๐Ÿ“ Phoenix๐Ÿ“ Duarte๐Ÿ“ Irvine National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Magnetic Resonance Imaging, Placebo Administration, Selinexor, Temozolomide Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma NCT05929495Phase 21 site๐Ÿ“ Milan University of Milano Bicocca ยท Tests: Metformin [177Lu]Lu-DOTA-EB-RGD2 Therapy in Patients With Recurrent High-grade Glioma NCT07655869EARLY Phase 12 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Beijing Tiantan Hospital ยท Tests: [177Lu]Lu-DOTA-EB-RGD2 The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma NCT06273176n/a8 sites๐Ÿ“ San Francisco๐Ÿ“ Boston๐Ÿ“ Leuven Erasmus Medical Center ยท Tests: Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia withoโ€ฆ TTFields Plus FET-PET-Guided Stereotactic Radiosurgery Versus TTFields Alone for Recurrent Glioblastoma (Tarrget 2.0) NCT07668869NA1 site๐Ÿ“ Bydgoszcz Prof. Franciszek Lukaszczyk Memorial Oncology Center ยท Tests: Tumor Treating Fields (TTFields), FET-PET-Guided Stereotactic Radiosurgery Dosimetry, Safety, and Efficacy Study of [177Lu]Lu-XT771 in Patients With Recurrent Glioblastoma NCT07648823EARLY Phase 12 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Beijing Tiantan Hospital ยท Tests: [177Lu]Lu-XT771 Analyzing and Solving Exceptional Long-term Survivors in Solid Tumors With Poor Prognosis NCT06160596n/a1 site๐Ÿ“ Villejuif Cure 51 ยท Tests: Long term survival multimodal analysis GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma NCT07301268Phase 21 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Bispecific CD80-lgG4Fc-IL-2v Fusion Protein GI-102, Computed Tomography, Echocardiography Test,โ€ฆ Evaluate the Efficacy and Safety of Atorvastatin Combined With Temozolomide in the Treatment of Glioblastoma NCT06327451Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University General Hospital ยท Tests: Atorvastatin 20mg The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201) NCT06118723n/a8 sites๐Ÿ“ San Francisco๐Ÿ“ Boston๐Ÿ“ Leuven Jasper Gerritsen ยท Tests: Supramaximal resection, Maximal safe resection Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing Craniotomy NCT05789394Phase 11 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Allogeneic Adipose-derived Mesenchymal Stem Cells, Biospecimen Collection, Craniotomy, Magnetic Resonance Imaging, Ommaโ€ฆ Evaluate the Efficacy and Safety of ADCV01 as an Add-On Treatment for Primary Glioblastoma Multiforme (GBM) Patients NCT04115761Phase 23 sites๐Ÿ“ Taichung๐Ÿ“ Taoyuan๐Ÿ“ Taichung Ever Supreme Bio Technology Co., Ltd. ยท Tests: autologous dendritic cells Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial NCT06319027Phase 218 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ Jacksonville ECOG-ACRIN Cancer Research Group ยท Tests: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging, Fluciclovine F18, Gadolinium-Chelate, Magnetic Resโ€ฆ ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial NCT07089641Phase 12 sites๐Ÿ“ Los Angeles๐Ÿ“ New York Jonsson Comprehensive Cancer Center ยท Tests: Biospecimen Collection, Echocardiography Test, EGFR Inhibitor ERAS-801, Fludeoxyglucose F-18, Magnetic Resonance Imaging Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas NCT04623931Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Quality-of-Life Assessment, Questionnaire Administration, Radiation Therapy, Temozolomide
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