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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Glioblastoma, Recurrent

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site📍 Boadilla del Monte Fundación de investigación HM · Tests: Olaparib; 177Lu-DOTATATE Sonodynamic Therapy in Patients With Recurrent GBM NCT06039709Phase 11 site📍 Charlottesville Shayan Moosa, MD · Tests: 5-ALA and Low-Intensity Focused Ultrasound (SDT) Predictive Value of Soluble CD146 in Glioblastoma Patients NCT06001281NA1 site📍 Marseille Assistance Publique Hopitaux De Marseille · Tests: plasma collection Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas NCT07544992Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Echocardiography Test, FDG… Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma NCT06815029Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Biospecimen Collection, Chimeric Antigen Receptor T-Cell Therapy, Echocardiography, Fludeoxyglucose F-18, Intracranial … Evaluating Safety, Tolerability, and Preliminary Efficacy of YSCH-01 Monotherapy and in Combination With Atezolizumab for Recurrent Glioblastoma NCT07538128EARLY Phase 11 site📍 Shanghai Huashan Hospital · Tests: YSCH-01, Atezolizumab (1200 mg every three weeks) BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma NCT04903795Phase 11 site📍 Durham Mustafa Khasraw, MBChB, MD, FRCP, FRACP · Tests: hEGFRvIII-CD3 (BRiTE) A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM NCT05303467Phase 19 sites📍 Birmingham📍 San Diego📍 San Francisco Boston Scientific Corporation · Tests: TheraSphere GBM Multiple Intracerebral Doses of Neural Stem Cell-Based Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas NCT05139056Phase 14 sites📍 Duarte📍 Stanford📍 Chicago City of Hope Medical Center · Tests: Neural Stem Cells-expressing CRAd-S-pk7, Resection Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature NCT06894225Phase 21 site📍 Singapore National Neuroscience Institute · Tests: ACT001 Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain Metastases NCT05911230NA1 site📍 Basel University Hospital, Basel, Switzerland · Tests: Advanced diffusion-weighted MRI (ADW-MRI) Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) NCT04427384n/a54 sites📍 Phoenix📍 Little Rock📍 Castro Valley GT Medical Technologies, Inc. · Tests: GammaTile A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases NCT07268053EARLY Phase 11 site📍 Phoenix Nader Sanai · Tests: Risvutatug rezetecan Intraarterial Carboplatin + Caelyx vs Intraarterial Carboplatin + Etoposide Phosphate for Progressing Glioblastoma NCT06356883Phase 21 site📍 Sherbrooke Université de Sherbrooke · Tests: IA Carboplatin + IA Caelyx, IA Carboplatin + IA Etoposide Phosphate GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma NCT06815432Phase 11 site📍 Houston Baylor College of Medicine · Tests: 15.GPC3-CAR T cells Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors NCT05283330Phase 18 sites📍 Chicago📍 Iowa City📍 Lexington Orano Med Theranostics, SAS · Tests: ²¹²Pb-DOTAM-GRPR1 ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors NCT04732065Phase 17 sites📍 San Francisco📍 Washington D.C.📍 Atlanta Sabine Mueller, MD, PhD · Tests: ONC206, Standard of Care Radiation Therapy, Optional Proton (1H) MR spectroscopy (MRS) A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma NCT07579208Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: NK Cells, NK Cells A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST Trial NCT07074756NA2 sites📍 Jacksonville📍 Rochester Mayo Clinic · Tests: Chemotherapy, Computed Tomography, Internet-Based Intervention, Magnetic Resonance Imaging, Neurologic Examination Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… · Tests: LMP744, Conventional Surgery or Biopsy A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma NCT06672575Phase 1, Phase 22 sites📍 Houston📍 Houston M.D. Anderson Cancer Center · Tests: Ivonescimab A Study of BL-B01D1 in Patients With Recurrent Glioblastoma NCT06598787Phase 21 site📍 Beijing Sichuan Baili Pharmaceutical Co., Ltd. · Tests: BL-B01D1 for Injection A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma NCT05698524Phase 11 site📍 Omaha University of Nebraska · Tests: PCI 24781, Temozolomide A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent Glioblastoma NCT07297212Phase 26 sites📍 Beijing📍 Chongqing📍 Jinan BioNTech SE · Tests: Pumitamig, Bevacizumab, Temozolomide Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme NCT00083512n/a1 site📍 Bethesda National Cancer Institute (NCI) A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma NCT06552260EARLY Phase 13 sites📍 Boston📍 Boston📍 Boston Ugonma Chukwueke · Tests: Troriluzole CARv3-TEAM-E T Cells in Glioblastoma NCT05660369Phase 11 site📍 Boston Marcela V. Maus, M.D.,Ph.D. · Tests: CARv3-TEAM-E T cells A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… Tris-CAR-T Cell Therapy for Recurrent Glioblastoma NCT05577091Phase 11 site📍 Beijing Beijing Tiantan Hospital · Tests: Inverse correlated dual-target, truncated IL7Ra modified CAR -expressing autologous T-lymphocytes. Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma NCT07551336Phase 11 site📍 Shenzhen Beijing Biotech · Tests: Dual-target CAR-NK cells, Cyclophosphamide, Intracranial catheter/reservoir for locoregional delivery, Fludarabine
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