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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Grade II Glioma

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site📍 Boadilla del Monte Fundación de investigación HM · Tests: Olaparib; 177Lu-DOTATATE A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma NCT04166409Phase 3132 sites📍 Birmingham📍 Mesa📍 Phoenix National Cancer Institute (NCI) · Tests: Biospecimen Collection, Carboplatin, Echocardiography Test, Magnetic Resonance Imaging, Questionnaire Administration Injection of Active Allogeneic Natural Killer Cells in Patients With Gliomas NCT06687681Phase 21 site📍 Tehran Marzieh Ebrahimi · Tests: NK cell therapy Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma NCT04540107Phase 11 site📍 San Francisco Susan Chang · Tests: Hyperpolarized Carbon C 13 Pyruvate, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopic Imaging Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume) NCT06159478Phase 26 sites📍 Kashiwa📍 Sapporo📍 Kyoto National Cancer Center, Japan · Tests: Binimetinib 15 MG Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… · Tests: LMP744, Conventional Surgery or Biopsy Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy NCT05180825Phase 225 sites📍 Amiens📍 Angers📍 Besançon University Hospital, Strasbourg, France · Tests: Trametinib, Vinblastine Measure of the Potential Evoked by Electric Stimulation NCT02509442NA1 site📍 Montpellier University Hospital, Montpellier · Tests: Diffusion of direct electric stimulation A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma NCT06410248Phase 11 site📍 Chicago Northwestern University · Tests: Biospecimen Collection, Magnetic Resonance Imaging, Questionnaire Administration, Resection, Temozolomide Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma NCT06468176NA8 sites📍 Montpellier📍 Amiens📍 Bordeaux Institut du Cancer de Montpellier - Val d'Aurelle · Tests: Cognitive Behavioral Therapy (CBT) neuropsychologist Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas NCT06381570EARLY Phase 11 site📍 Toronto Daniel Morgenstern · Tests: Tovorafenib, Vinblastine Vorasidenib Maintenance for IDH Mutant Astrocytoma NCT06809322Phase 359 sites📍 Bedford Park📍 Camperdown📍 Heidelberg European Organisation for Research and Treatment of Cancer … · Tests: Vorasidenib, Vorasidenib Placebo Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade Gliomas NCT05768919Phase 1, Phase 22 sites📍 Washington D.C.📍 Baltimore SignPath Pharma, Inc. · Tests: Treatment Period 1, Treatment Period 2, Treatment Period 3, Treatment Period 4a Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021) NCT04485559Phase 117 sites📍 Birmingham📍 Los Angeles📍 San Diego University of California, San Francisco · Tests: Everolimus, Trametinib ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas NCT06838676Phase 220 sites📍 Aurora📍 Washington D.C.📍 Miami Nationwide Children's Hospital · Tests: ACT001 A Clinical Study to Improve Brain Function and Quality of Life of Patients With Newly Diagnosed Brain Tumors (Gliomas). NCT05331521Phase 319 sites📍 Heidelberg📍 Berlin📍 Bochum University Hospital Heidelberg · Tests: CETEG, PCV, RT HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM NCT03596086Phase 1, Phase 21 site📍 Houston David Baskin MD · Tests: ADV/HSV-tk (gene therapy) Proton vs. Photon Radiotherapy for Patients With WHO Grade 2-3 Glioma NCT07750457NA2 sites📍 Essen📍 Giessen University Hospital, Essen · Tests: Proton therapy, Photon therapy Implantable Microdevice In Primary Brain Tumors NCT04135807EARLY Phase 11 site📍 Boston Oliver Jonas · Tests: Microdevice Clinical Study of Carbon Ion Radiotherapy for High-grade Glioma NCT06831773NA1 site📍 Wuwei Gansu Wuwei Tumor Hospital · Tests: Carbon ion combined with photon radiotherapy Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas NCT04623931Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Quality-of-Life Assessment, Questionnaire Administration, Radiation Therapy, Temozolomide Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared NCT07547163n/a1 site📍 Milan Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Tests: Vorasidenib, Radiotherapy, active surveillance A Study of 177Lu-PSMA-617 in People With Gliomas NCT07223034Phase 17 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Temozolomide, 177Lu-PSMA-617, 68Ga-PSMA-PET scan/ MRI, Quality of Life Questionnaires A Vaccine Trial for Low Grade Gliomas NCT02358187Phase 21 site📍 Pittsburgh James Felker · Tests: Experimental: HLA-A2 Restricted Glioma Antigen-Peptides with Poly-ICLC PRO-GLIO: PROton Versus Photon Therapy in IDH-mutated Diffuse Grade II and III GLIOmas NCT05190172NA1 site📍 Oslo Oslo University Hospital · Tests: Radiation therapy Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas NCT06964737Phase 11 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Anti-GARP Chimeric Antigen Receptor-T Cells, Biospecimen Collection, Chest Radiography, Echocardiography Test, Magnetic… Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma NCT07091864NA3 sites📍 Phoenix📍 Jacksonville📍 Rochester Mayo Clinic · Tests: Best Practice, Biospecimen Collection, Dietary Intervention, Glucose Measurement, Magnetic Resonance Imaging Study of Pembrolizumab and M032 (NSC 733972) NCT05084430Phase 1, Phase 21 site📍 Birmingham University of Alabama at Birmingham · Tests: M032, Pembrolizumab Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease NCT07703436Phase 212 sites📍 Los Angeles📍 San Francisco📍 New Haven Nuvation Bio Inc. · Tests: Safusidenib
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