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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for HER2 Positive Early Breast Cancer

Pyrotinib Plus Trastuzumab and Chemotherapy for HER2-Positive Early Breast Cancer NCT07635342Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: Pyrotinib Maleate, Trastuzumab (H, 8mg/kg, pegylated liposomal doxorubicin hydrochloride, Cyclophosphamide, Paclitaxel โ€ฆ I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer NCT01042379Phase 242 sites๐Ÿ“ Birmingham๐Ÿ“ Scottsdale๐Ÿ“ Tucson QuantumLeap Healthcare Collaborative ยท Tests: Standard Therapy, AMG 386 with or without Trastuzumab, AMG 479 (Ganitumab) plus Metformin, MK-2206 with or without Trasโ€ฆ The Efficacy and Safety of Pyrotinib, Trastuzumab Combined With Taxanes in the Treatment of Trastuzumab-treated HER2+ Advanced Breast Cancer (ABC). NCT06217185Phase 41 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: Pyrotinib, Trastuzumab, Taxanes, Capecitabine Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer NCT07214532NA49 sites๐Ÿ“ Phoenix๐Ÿ“ Scottsdale๐Ÿ“ Tucson Natera, Inc. ยท Tests: ctDNA-Guided Treatment Strategy Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies NCT07211178n/a16 sites๐Ÿ“ Birmingham๐Ÿ“ Whittier๐Ÿ“ Weston Tempus AI ยท Tests: There are no interventions in this observational study. JUdicious Surveillance for Trastuzumab Induced Cardiotoxicity in the First Year NCT06930521NA1 site๐Ÿ“ Toronto Women's College Hospital ยท Tests: Intervention - Low Risk Group OR Intermediate Risk Group Evaluation of [68Ga]Ga-NOTA-anti-HER2-sdAb PET/CT for Predicting Pathological Complete Response After Neoadjuvant Chemotherapy in HER2 Positive Early Breast Cancer NCT07593976Phase 21 site๐Ÿ“ Rouen Centre Henri Becquerel ยท Tests: [68Ga]Ga-NOTA-anti-HER2-sdAb Positron Emission Tomography Neoadjuvant Adebrelimab and Chemotherapy in High-rish ER+/HER2- BC NCT06500208Phase 21 site๐Ÿ“ Shanghai Shanghai Jiao Tong University School of Medicine ยท Tests: Adebrelimab combined with nab-paclitaxel, epirubicin and cyclophosphamide Adjuvant Therapy Choice for Non-pCR HER2 Positive Early Breast Cancer After Neoadjuvant Therapy NCT06693037n/a1 site๐Ÿ“ Beijing Shu Wang Tirzepatide Weight Loss for MRD+ Early Breast Cancer NCT06517212Phase 21 site๐Ÿ“ Dallas Baylor Research Institute ยท Tests: Tirzepatide A Study to Assess Treatment Patterns and Treatment Adherence in Early HER2-positive Breast Cancer Participants After Treatment Decentralization NCT07527741n/a10 sites๐Ÿ“ Loznica๐Ÿ“ Poลพarevac๐Ÿ“ Bor Hoffmann-La Roche Adjuvant Trastuzumab Plus Neratinib in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer After Neoadjuvant Trastuzumab Plus Pertuzumab NCT05760612Phase 31 site๐Ÿ“ Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ยท Tests: Trastuzumab and neratinib, Trastuzumab and Pertuzumab Efficacy and Safety of Dalpiciclib With Endocrine Therapy as Adjuvant Treatment in HR+/ HER2- Early Breast Cancer NCT06341894Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: Dalpiciclib, Endocrine therapy Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer NCT04481932Phase 21 site๐Ÿ“ Beijing Peking University ยท Tests: Trastuzumab combined with Pyrotinib and chemotherapy Pyrotinib in Women With High-risk in Early Stage Breast Cancer NCT05834764Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: Pyrotinib Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer NCT06106477NA1 site๐Ÿ“ Milwaukee Medical College of Wisconsin ยท Tests: Intermittent Fasting EC-THP Versus TCbHP in HER2-positive Lymph Node Positive Early Breast Cancer NCT05883852Phase 31 site๐Ÿ“ Shanghai Fudan University ยท Tests: Docetaxel, carboplatin, Trastuzumab, Pertuzumab, Epirubicin ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast Cancer NCT06970912Phase 21 site๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: Dalpiciclib + Aromatase Inhibitor with ctDNA-Guided Therapy, Taxane-Based Neoadjuvant Chemotherapy Dalpiciclib With or Without Entinostat and Letrozole in HR+/HER2- Early Breast Cancer NCT07492394Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: entinostat, Dalpiciclib, Letrozole Short-course Trastuzumab, Pertuzumab with Taxanes in the Adjuvant Treatment of Early HER2-positive Breast Cancer NCT05891561Phase 21 site๐Ÿ“ Shanghai Shanghai Jiao Tong University School of Medicine ยท Tests: Pertuzumab Trastuzumab Rezetecan Neoadjuvant Therapy in THP-Insensitive HER2-Positive Early Breast Cancer NCT07647263Phase 21 site๐Ÿ“ Suzhou The First Affiliated Hospital of Soochow University ยท Tests: THP Regimen (Taxane + Trastuzumab + Pertuzumab), Trastuzumab Rezetecan (SHR-A1811) Fovinaciclib Plus Aromatase Inhibitors and Dual HER2 Blockade in a Response-Adapted Neoadjuvant Strategy for HR-Positive/HER2-Positive Early Breast Cancer NCT07616427Phase 23 sites๐Ÿ“ Nanjing๐Ÿ“ Hangzhou๐Ÿ“ Ningbo Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Fovinaciclib, Aromatase Inhibitors, Trastuzumab + Pertuzumab Asian Multicenter Prospective Study in HER2 Positive Early Breast Cancer for Detecting MRD by ctDNA;HARMONY Study NCT05433753n/a1 site๐Ÿ“ Chuo-ku National Cancer Center, Japan Ablation Compare With Surgery for Early Breast Cancer NCT07484087NA1 site๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: breast conserving surgery, cryo-thermal ablation Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial NCT07407920Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Biospecimen Collection, Hormone Therapy, Pembrolizumab, Pertuzumab, Trastuzumab Diagnostic HER2DX-guided Treatment for Patients wIth Early-stage HER2-positive Breast Cancer NCT06446882NA29 sites๐Ÿ“ Graz๐Ÿ“ Leoben๐Ÿ“ Linz Fundacio Clinic Barcelona ยท Tests: Personalized treatment according to molecular diagnosis with HER2DX, Treatment by physicianยดs choice, blinded to the diโ€ฆ Neoadjuvant Trastuzumab-rezetecan Plus Pertuzumab or Nab-Paclitaxel, Carboplatin, Trastuzumab, and Pyrotinib After Suboptimal Response to Neoadjuvant Dual HER2-Targeted Therapy Combined With Chemotherapy in HER2-Positive Early Breast Cancer NCT07340398Phase 21 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Nab paclitaxel, Carboplatin, Trastuzumab, Pertuzumab, SHR-A1811 A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence NCT06492616Phase 3567 sites๐Ÿ“ Daphne๐Ÿ“ Chandler๐Ÿ“ Gilbert Stemline Therapeutics, Inc. ยท Tests: Elacestrant, Anastrozole, Letrozole, Exemestane, Tamoxifen Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer NCT05020860Phase 22 sites๐Ÿ“ Houston๐Ÿ“ Houston Baylor Breast Care Center ยท Tests: Paclitaxel, Carboplatin, Trastuzumab, Pertuzumab, Doxorubicin fREEDOM: REsonance for Early Detection Of Breast Cancer Metastases NCT06328465NA1 site๐Ÿ“ Milan European Institute of Oncology ยท Tests: Diffusion whole body MRI
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