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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for HER2-Gastric/Gastroesophageal Junction Cancer

First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2) NCT06730373Phase 220 sites๐Ÿ“ Zhengzhou๐Ÿ“ Binzhou๐Ÿ“ Dongying Qilu Hospital of Shandong University ยท Tests: Disitamab Vedotin, Sintilimab, S-1, Trastuzumab, Oxaliplatin IKS014 in Advanced Solid Tumors That Express HER2 NCT05872295Phase 113 sites๐Ÿ“ Newport Beach๐Ÿ“ Boston๐Ÿ“ Nashville Iksuda Therapeutics Ltd. ยท Tests: IKS014 Ph1b/2 Study of the Safety and Efficacy of SHR-A1811 Combinations in Advanced HER2 Expression Gastric Cancer NCT05671822Phase 21 site๐Ÿ“ Shanghai Suzhou Suncadia Biopharmaceuticals Co., Ltd. ยท Tests: SHR-A1811 and SHR-1701, SHR-A1811 and capecitabine, SHR-A181, SHR-1701, and capecitabine, SHR-A1811, SHR-1316, and capeโ€ฆ KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy NCT05427383Phase 2, Phase 31 site๐Ÿ“ Beijing Shanghai JMT-Bio Inc. ยท Tests: KN026/Placbo Injection, Paclitaxel Injection, Docetaxel Injection, Irinotecan Injection BC001 in Combination with Sintilimab and XELOX in the Treatment of HER-2 Negative Advanced or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma. NCT06773312Phase 11 site๐Ÿ“ Beijing Sichuan Luzhou Buchang Biopharmaceutical Co., Ltd. ยท Tests: BC001+Sintilimab+XELOX Phase 2 Trial of KN026+KN046ยฑXELOX in HER2-positive Locally Advanced GC NCT06023758Phase 21 site๐Ÿ“ Beijing Peking University ยท Tests: KN026, KN046, XELOX A Phase โ…ข Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer NCT06764875Phase 3304 sites๐Ÿ“ Anchorage๐Ÿ“ Phoenix๐Ÿ“ Duarte AstraZeneca ยท Tests: Rilvegostomig, Trastuzumab deruxtecan, Trastuzumab, Pembrolizumab, 5-fluorouracil A Phase 2 Clinical Study of ABSK061 and ABSK043 NCT06632262Phase 221 sites๐Ÿ“ Guiyang๐Ÿ“ Guiyang๐Ÿ“ Shijiazhuang Abbisko Therapeutics Co, Ltd ยท Tests: ABSK061 + ABSK043, ABSK061+ABSK043 in combination with CAPOX IBI343 Combined With Sintilimab Plus Chemotherapy in Gastric Cancer NCT07025889Phase 1, Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: IBI343, Sintilimab, Oxaliplatin, S-1 T-Dxd in Combination With Ramucirumab as HER2 Low Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma NCT05894824Phase 1, Phase 21 site๐Ÿ“ Seoul Yonsei University ยท Tests: T-Dxd(Trastuzmab deruxtecan), Ramucirumab Perioperative Disitamab Vedotin Plus Toripalimab and XELOX in Gastric or Gastroesophageal Junction Adenocarcinoma. NCT06155383Phase 211 sites๐Ÿ“ Beijing๐Ÿ“ Fuzhou๐Ÿ“ Kunming RemeGen Co., Ltd. ยท Tests: Capecitabine, oxaliplatin, Disitamab Vedotin, Toripalimab Comparing Modified XELOX Plus Sintilimab With Standard XELOX Plus Sintilimab in First-line Treatment for HER2-negative Gastric/Gastroesophageal Junction Adenocarcinoma NCT05918094Phase 310 sites๐Ÿ“ Guangzhou๐Ÿ“ Guiyang๐Ÿ“ Harbin Sun Yat-sen University ยท Tests: Experimental dose: modified XELOX + sintilimab, Standard dose: standard XELOX + sintilimab Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Gastroesophageal Cancers NCT07464470n/a1 site๐Ÿ“ Moscow Blokhin's Russian Cancer Research Center ยท Tests: HER2 Testing, MSI Testing, PD-L1 Testing, CLDN18.2 Testing Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors NCT06293898Phase 126 sites๐Ÿ“ Birmingham๐Ÿ“ Duarte๐Ÿ“ Los Angeles SystImmune Inc. ยท Tests: BL-M07D1 Disitamab Vedotin Plus Trastuzumab in Patients With HER2 Positive GC/GEJ Patiens NCT06572319Phase 1, Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: Disitamab Vedotin(RC48) Plus Tratuzumab A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer. NCT06902545n/a15 sites๐Ÿ“ Goyang-si๐Ÿ“ Suwon๐Ÿ“ Suwon Astellas Pharma Korea, Inc. ยท Tests: zolbetuximab A Phase โ…ข Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer NCT06532006Phase 3208 sites๐Ÿ“ Anaheim๐Ÿ“ Los Alamitos๐Ÿ“ Greeley Shanghai Henlius Biotech ยท Tests: HLX22, Pembrolizumab, Trastuzumab, Oxaliplatin, Capecitabine Cadonilimab Combination Regimen as First-line Treatment for HER2-expressing GC/GEJ Patients NCT06650332Phase 1, Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: cadonilimab, Trastuzumab, XELOX, Disitamab Vedotin, mFOLFOX6 A Study of Fruquintinib Plus Chemotherapy for Postoperative Treatment of HER2-Negative Gastric Cancer With Poor TRG NCT06774222Phase 21 site๐Ÿ“ Zhengzhou Henan Cancer Hospital ยท Tests: Fruquintinib A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer NCT06901531Phase 3252 sites๐Ÿ“ Birmingham๐Ÿ“ Bakersfield๐Ÿ“ Cerritos Astellas Pharma Global Development, Inc. ยท Tests: zolbetuximab, Pembrolizumab, Capecitabine, Oxaliplatin, Folinic acid (leucovorin or local equivalent) Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination With or Without Nivolumab for the 1L Treatment of Participants With HER2-negative, Previously Untreated, Unresectable or Metastatic Gastric/GEJ Adenocarcinoma NCT07700979Phase 325 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ Denver Akeso ยท Tests: Cadonilimab, CAPOX regimen, Nivolumab, Placebo Fruquintinib Combined With Trastuzumab and XELOX as First-line Treatment in Patients With HER2-positive Advanced Gastric Cancer NCT07334431Phase 1, Phase 21 site๐Ÿ“ Zhengzhou Henan Cancer Hospital ยท Tests: fruquintinib๏ผ‹trastuzumab + XELOX M108 Plus CAPOX Versus Placebo Plus CAPOX as First-line Treatment for Claudin (CLDN) 18.2-Positive, HER2-Negative, PD-L1 CPS<5, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma. NCT06177041Phase 31 site๐Ÿ“ Beijing FutureGen Biopharmaceutical (Beijing) Co., Ltd ยท Tests: M108 monoclonal antibody, Placebo, Oxaliplatin, Capecitabine A Study on the Safety and Efficacy of the Combination of Candenizumab, Lenvatinib, and SOX Regimen in the Treatment of HER2 Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Patients NCT06277024NA1 site๐Ÿ“ Fuzhou Fujian Medical University ยท Tests: Combination of Cardonizumab with Lenvatinib and SOX regimen A Study of Disitamab Vedotin Combined With Trastuzumab and Tislelizumab Versus Chemotherapy Combined With Trastuzumab With or Without Pembrolizumab in HER2-high Expression Advanced Gastric or Gastroesophageal Junction Adenocarcinoma. NCT07315750Phase 31 site๐Ÿ“ Beijing RemeGen Co., Ltd. ยท Tests: Disitamab Vedotin, Tislelizumab, CAPOX (oxaliplatin/capecitabine), Trastuzumab, Pembrolizumab Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors NCT07660055Phase 15 sites๐Ÿ“ Omaha๐Ÿ“ Darlinghurst๐Ÿ“ Montreal Novartis Pharmaceuticals ยท Tests: [68Ga]Ga-DWJ155, [177Lu]Lu-DWJ155 Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread NCT06324357Phase 1, Phase 2104 sites๐Ÿ“ Cerritos๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Boehringer Ingelheim ยท Tests: Zongertinib, Trastuzumab deruxtecan, Trastuzumab emtansine, Trastuzumab, Capecitabine A Study of PD-1 Inhibitors Combined With Fruquintinib and Chemotherapy in First-line Treatment of HER2-negative Advanced G/GEJ Cancer NCT06158919NA1 site๐Ÿ“ Shanghai Fudan University ยท Tests: Fruquintinibใ€Nivolumabใ€Sintilimabใ€Oxaliplatinใ€Teysunoใ€Capecitabine mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma NCT05677490Phase 3798 sites๐Ÿ“ Birmingham๐Ÿ“ Anchorage๐Ÿ“ Anchorage Alliance for Clinical Trials in Oncology ยท Tests: Fluorouracil, Leucovorin Calcium, Oxaliplatin, Irinotecan, Nivolumab A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Whittier Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan
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