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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for HPV Positive Oropharyngeal Squamous Cell Carcinoma

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites📍 Tampa📍 Chicago📍 Fairway National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN) NCT07209189Phase 21 site📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Toripalimab + Chemotherapy, Toripalimab, Chemoradiotherapy or radiation TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites📍 Atlanta📍 Atlanta Emory University · Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Res… Reduced Elective Nodal and CTV Dose for HPV+ Oropharyngeal Squamous Cell Carcinoma NCT07497607Phase 21 site📍 Cincinnati Sara Medek · Tests: Cisplatin, Radiotherapy Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma NCT03875716NA1 site📍 Boston Dana-Farber Cancer Institute · Tests: Radiation therapy De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE) NCT06307015NA1 site📍 Saint Leonards Royal North Shore Hospital · Tests: De-escalation, Standard of care A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer NCT06319963Phase 1, Phase 24 sites📍 Orlando📍 Tampa📍 Tampa Theravectys S.A. · Tests: Two IM injections Lenti-HPV-07, One IM injection Lenti-HPV-07 Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL) NCT06088381Phase 25 sites📍 Baltimore📍 Baltimore📍 Bel Air University of Maryland, Baltimore · Tests: Experimental Observation, Observation per Standard of Care, Adjuvant Treatment per Standard of Care, Circulating Tumor … Intranasal WSK-IM05 Vaccine Plus Tislelizumab as Neoadjuvant Therapy for HPV+ OPSCC NCT07565740Phase 11 site📍 Chengdu West China Hospital · Tests: WSK-IM05 (4×10^10 vp), WSK-IM05 (8×10^10 vp), WSK-IM05 (1.6x10^11 vp), Tislelizumab Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites📍 Tucson📍 Tucson📍 Irvine National Cancer Institute (NCI) · Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography CUE-101with Pembrolizumab for Locally Advanced HPV+HNSCCs NCT07172256Phase 21 site📍 New Haven Yale University · Tests: CUE-101, Pembrolizumab Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study NCT06115772n/a1 site📍 Rochester Mayo Clinic · Tests: Non-Interventional Study Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer NCT06532279Phase 2153 sites📍 Gilbert📍 Peoria📍 Phoenix NRG Oncology · Tests: Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery NCT06747390Phase 11 site📍 Philadelphia Ryan Carey · Tests: Lidocaine 1% Injectable Solution ctHPVDNA in HPV Positive Squamous Cell Carcinoma of the Oropharynx NCT06915038NA2 sites📍 Carmel📍 Indianapolis Indiana University · Tests: NavDx, Adjuvant Radiation 30 Gray, Adjuvant Radiation 40 Gray A Study Comparing Personalized Radiation Therapy With Standard Radiation Therapy in People With HPV-Positive Throat Cancer NCT06563479Phase 39 sites📍 Hartford📍 Miami📍 Basking Ridge Memorial Sloan Kettering Cancer Center · Tests: FMISO-PET Scan, Chemoradiation, Chemoradiation, Assessments Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer NCT06323460Phase 21 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Biospecimen Collection, Carboplatin, Cisplatin, Computed Tomography, External Beam Radiation Therapy The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial) NCT05419089Phase 22 sites📍 Paramus📍 New York Icahn School of Medicine at Mount Sinai · Tests: Robotic surgery De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA NCT05541016Phase 23 sites📍 Scottsdale📍 Jacksonville📍 Rochester Mayo Clinic · Tests: Biospecimen Collection, Cisplatin, Computed Tomography, Diffusing Alpha-emitter Radiation Therapy, Docetaxel Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus NCT05918510n/a1 site📍 Rome Regina Elena Cancer Institute · Tests: Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx NCT05600842n/a1 site📍 Orange University of California, Irvine · Tests: Intensity-Modulated Radiation Therapy (IMRT) Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma NCT07156227Phase 13 sites📍 Duarte📍 Irvine📍 Pittsburgh National Cancer Institute (NCI) · Tests: Biospecimen Collection, Camonsertib, Computed Tomography, Positron Emission Tomography, Stereotactic Body Radiation The… Oropharynx (OPX) Biomarker Trial NCT06356272n/a1 site📍 Rochester Mayo Clinic · Tests: Non-Interventional Study E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers NCT05639972Phase 1, Phase 22 sites📍 New Brunswick📍 New Brunswick Christian Hinrichs · Tests: E7 TCR-T cells, Aldesleukin Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation NCT06662058NA1 site📍 Atlanta Emory University · Tests: Audiometric Test, Audiometric Test, Audiometric Test, Interview Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial NCT06636734Phase 22 sites📍 Atlanta📍 Atlanta Emory University · Tests: Biospecimen Collection, Computed Tomography, Lovastatin, Magnetic Resonance Imaging, Pembrolizumab E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers NCT05686226Phase 23 sites📍 Bethesda📍 New Brunswick📍 New Brunswick Christian Hinrichs · Tests: E7 TCR-T cells, Aldesleukin Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer NCT06914999EARLY Phase 11 site📍 Atlanta Emory University · Tests: Computed Tomography, Fludeoxyglucose F-18, Intensity-Modulated Proton Therapy, Intensity-Modulated Radiation Therapy, P… BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study NCT05136196Phase 2232 sites📍 Phoenix📍 Little Rock📍 Beverly Hills National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate, Computed Tomography, Magnetic Resonance Imaging A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC) NCT07063212Phase 27 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Sacituzumab Govitecan, Cetuximab
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