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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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18 recruiting trials

for HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN) NCT07209189Phase 21 site📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Toripalimab + Chemotherapy, Toripalimab, Chemoradiotherapy or radiation Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma NCT03875716NA1 site📍 Boston Dana-Farber Cancer Institute · Tests: Radiation therapy De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE) NCT06307015NA1 site📍 Saint Leonards Royal North Shore Hospital · Tests: De-escalation, Standard of care A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer NCT06319963Phase 1, Phase 24 sites📍 Orlando📍 Tampa📍 Tampa Theravectys S.A. · Tests: Two IM injections Lenti-HPV-07, One IM injection Lenti-HPV-07 CUE-101with Pembrolizumab for Locally Advanced HPV+HNSCCs NCT07172256Phase 21 site📍 New Haven Yale University · Tests: CUE-101, Pembrolizumab Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study NCT06115772n/a1 site📍 Rochester Mayo Clinic · Tests: Non-Interventional Study Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery NCT06747390Phase 11 site📍 Philadelphia Ryan Carey · Tests: Lidocaine 1% Injectable Solution Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION) NCT07513389Phase 21 site📍 Charleston Medical University of South Carolina · Tests: Active Surveillance With ctHPVDNA (NavDx®) Patients With Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical Intervention NCT06821243n/a1 site📍 Rome Regina Elena Cancer Institute Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer NCT06323460Phase 21 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Biospecimen Collection, Carboplatin, Cisplatin, Computed Tomography, External Beam Radiation Therapy Phase 1 Clinical Trial of FluBHPVE6E7 Immunotherapy for HPV16-Associated Oropharyngeal Cancer NCT06589609Phase 11 site📍 Vienna BlueSky Immunotherapies GmbH · Tests: FluBHPVE6E7 E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers NCT05639972Phase 1, Phase 22 sites📍 New Brunswick📍 New Brunswick Christian Hinrichs · Tests: E7 TCR-T cells, Aldesleukin E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers NCT05686226Phase 23 sites📍 Bethesda📍 New Brunswick📍 New Brunswick Christian Hinrichs · Tests: E7 TCR-T cells, Aldesleukin Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer NCT06223568Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: Docetaxel, Cisplatin, PRGN-2009 Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC NCT04564989n/a3 sites📍 Rochester📍 Chapel Hill📍 North Charleston UNC Lineberger Comprehensive Cancer Center A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC) NCT05307939Phase 28 sites📍 Miami📍 Basking Ridge📍 Middletown Memorial Sloan Kettering Cancer Center · Tests: HPV ctDNA Assay, MRI Studies, EORTC QLQ H&N 35 and C30, MDADI-HN, COST-FACIT Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study NCT04900623Phase 22 sites📍 Boston📍 Boston Jonathan Schoenfeld, MD, MPH · Tests: NavDx HPV ctDNA Testing, Radiotherapy, Chemotherapy drug A Phase I/IIa Clinical Trial to Investigate BVAC-E6E7 in Subjects With HPV Positive HNSCC. NCT06797986Phase 1, Phase 22 sites📍 Seoul📍 Seoul Cellid Co., Ltd. · Tests: BVAC-E6E7 (low level), BVAC-E6E7 (high level), BVAC-E6E7 (RP2D)
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