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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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22 recruiting trials

for High Grade Neuroendocrine Neoplasms

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site📍 Boadilla del Monte Fundación de investigación HM · Tests: Olaparib; 177Lu-DOTATATE Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs) NCT06926634Phase 22 sites📍 Rochester📍 St Louis Washington University School of Medicine · Tests: Zanzalintinib A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity NCT06406465Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: Belinostat, Cisplatin, Etoposide Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites📍 Scottsdale📍 Bethesda📍 Columbus Novartis Pharmaceuticals · Tests: dabrafenib, trametinib IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors NCT05039801Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: Bevacizumab, Glutaminase-1 Inhibitor IACS-6274, Paclitaxel, Capivasertib Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C... NCT06161532Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: Sacituzumab govitecan, Atezolizumab An Investigational Scan ([68Ga] Ga-FAPI-04 PET/CT) for the Imaging of Patients With High-Grade Neuroendocrine Cancer NCT07132645EARLY Phase 11 site📍 Ann Arbor University of Michigan Rogel Cancer Center · Tests: Computed Tomography, Gallium Ga 68-DOTA-FAPI-04, Positron Emission Tomography Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients" NCT01365169NA1 site📍 Houston M.D. Anderson Cancer Center · Tests: Exercise Intervention, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring Sintilimab Combined With IBI310 and Surufatinib for the Treatment of G3-NET and NEC (NESSIE) NCT05165407Phase 22 sites📍 Beijing📍 Beijing Peking University · Tests: Sintilimab, IBI310, Surufatinib Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER) NCT06228066Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: Lurbinectedin, Avelumab Omitting Therapeutic Lymph Node Dissection in Patients With Melanoma (Stage 3) and Major Pathological Response in the Index Lymph Node NCT06754904NA1 site📍 Rotterdam D.J. (Dirk) Grünhagen · Tests: Omitting TLND, Index node procedure SVV-001 With Nivolumab and Ipilimumab in Patients With Poorly Differentiated Neuroendocrine Carcinomas (NEC) or Well-Differentiated High-Grade Neuroendocrine Tumors (NET) NCT06889493Phase 11 site📍 Miami Peter Hosein, MD · Tests: Seneca Valley Virus-001 (SVV-001), Nivolumab, Ipilimumab Screening Trial for Pain Relief in Schwannomatosis (STARFISH) NCT05684692Phase 21 site📍 Boston Massachusetts General Hospital · Tests: Siltuximab, Erenumab-Aooe, Siltuximab Matching Placebo, Erenumab-Aooe Matching Placebo Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease NCT07509034Phase 11 site📍 Bethesda National Cancer Institute (NCI) · Tests: Autologous B7-H3 CAR T, Cyclophosphamide, Fludarabine Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET NCT06784752Phase 367 sites📍 Scottsdale📍 Fayetteville📍 Denver Novartis Pharmaceuticals · Tests: [177Lu]Lu-DOTA-TATE, Octreotide LAR Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors NCT07517198Phase 13 sites📍 Los Angeles📍 Fort Worth📍 West Valley City Exscientia AI Ltd., a wholly owned subsidiary of Recursion … · Tests: EXS74539 Lenvatinib Plus Pembrolizumab in Well Differentiated G3 Neuroendocrine Tumors NCT05746208Phase 21 site📍 San Francisco University of California, San Francisco · Tests: Lenvatinib, Pembrolizumab, Hyperpolarized 13C-Pyruvate Pancreatic Radiofrequency Under High Echo-endoscopy in the Management of Pancreatic Neuroendocrine Tumors NCT04520932NA1 site📍 Marseille Institut Paoli-Calmettes · Tests: Radiofrequency ablation NALIRIFOX as Second-Line Chemotherapy in Extrapulmonary High-grade Neuroendocrine Neoplasms: a Prospective, Single-center, Single-arm Trial NCT07077551Phase 21 site📍 Hangzhou Second Affiliated Hospital, Zhejiang University, School of … · Tests: NALIRIFOX A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors NCT07115043Phase 1, Phase 213 sites📍 Grand Rapids📍 St Louis📍 Pittsburgh AstraZeneca · Tests: AZD6750, rilvegostomig CompArative Analysis Between, Thymic, pulmonaRy and Pancreatic Well Differentiated High Grade Neuroendocrine Tumors NCT07429851n/a1 site📍 Milan European Institute of Oncology Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors NCT07410494Phase 1, Phase 21 site📍 Beijing Essen Biotech · Tests: EB-SELECT Single-Target CAR-NK Cells, Dual-Target Antigen-Selected CAR-NK
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