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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for High Risk of Recurrence

Iparomlimab and Tuvonralimab as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With High Risk of Recurrence NCT06954116Phase 21 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: Iparomlimab and Tuvonralimab (QL1706), Partial hepatectomy Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma NCT06536049Phase 1, Phase 23 sites๐Ÿ“ Minneapolis๐Ÿ“ Columbus๐Ÿ“ Richmond Yazeed Sawalha ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Epcoritamab A Prospective Randomized Non-inferiority Trial Comparing Anti-CD20 Maintenance Versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis NCT07189325Phase 31 site๐Ÿ“ Montpellier University Hospital, Montpellier ยท Tests: Platform therapies (Dimethyl Fumarate, Teriflunomide, Glatiramer Acetate, Beta-interferons), Anti-CD20 therapies (Ocrelโ€ฆ Toripalimab Combined With Gemcitabine and Cisplatin (GemCis) as Preoperative Neoadjuvant Therapy for Resectable Intrahepatic Cholangiocarcinoma NCT06721286Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Teripalimab, Gemcitabine + Cisplatin, Surgery Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors NCT07174661NA1 site๐Ÿ“ Scottsdale Mayo Clinic ยท Tests: Advance Care Planning, Educational Intervention, Electronic Health Record Review, Survey Administration Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) Progression NCT06975332NA2 sites๐Ÿ“ Warsaw๐Ÿ“ Warsaw Medical University of Warsaw ยท Tests: Local, targeted therapy with alpha emitter [225Ac]Ac-DOTA-SP (TAT) CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome NCT04493164Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Ivosidenib, Liposome-encapsulated Daunorubicin-Cytarabine Adjuvant Rezvilutamide Monotherapy for High-Risk Prostate Cancer After Radical Prostatectomy NCT07711314Phase 21 site๐Ÿ“ Nanjing The Affiliated Nanjing Drum Tower Hospital of Nanjing Univeโ€ฆ ยท Tests: Rezvilutamide Tablets Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL NCT06806033Phase 253 sites๐Ÿ“ Anchorage๐Ÿ“ Clovis๐Ÿ“ Fullerton Hoffmann-La Roche ยท Tests: Obinutuzumab, Glofitamab, Gemcitabine, Oxaliplatin GOT Applied As Neoadjuvant Regimen for Patients of Resectable ICC with High-risk Factors of Recurrence NCT05557578Phase 22 sites๐Ÿ“ Hangzhou๐Ÿ“ Hanzhou Zhejiang Cancer Hospital ยท Tests: Tislelizumab combined with GEMOX (GOT) regimen Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer NCT06441110Phase 31 site๐Ÿ“ Fuzhou Fujian Medical University Union Hospital ยท Tests: Tislelizumab in Combination with Bacillus Calmette-Guรฉrin Efficacy and Safety of Icaritin Combined With mFOLFOX in Postoperative HCC With High-risk Recurrence Factors NCT07337460Phase 21 site๐Ÿ“ Yangzhou Northern Jiangsu People's Hospital ยท Tests: Icaritin Soft Capsules and mFOLFOX ๏ผšOxaliplatin,leucovorin calcium,5-fluorouracil Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell Histiocytosis in Children NCT07022834Phase 21 site๐Ÿ“ Chengdu West China Second University Hospital ยท Tests: Dabrafenib or Trametinib and Clofarabine Glofitamab Combined With Lenalidomide in High Risk Patients With Relapsed or Refractory Mantle Cell Lymphoma NCT07460362Phase 21 site๐Ÿ“ Beijing Peking University Third Hospital ยท Tests: Glofitamab, Lenalidomide Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma NCT06649812Phase 2114 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Los Angeles National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography Plasma Radiofrequency Ablation at Low Temperature Versus Electrocautery Block Resection at High Frequency for Localized Recurrent Nasopharyngeal Carcinoma NCT04425265NA3 sites๐Ÿ“ Guangzhou๐Ÿ“ Zhuhai๐Ÿ“ Nanchang Sun Yat-sen University ยท Tests: Plasma radiofrequency ablation, Electrocautery block resection [177Lu]Lu-DOTA-EB-RGD2 Therapy in Patients With Recurrent High-grade Glioma NCT07655869EARLY Phase 12 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Beijing Tiantan Hospital ยท Tests: [177Lu]Lu-DOTA-EB-RGD2 Safety, Tolerability, and Preliminary Efficacy of BH011 in Subjects With Non-Muscle-Invasive Bladder Cancer NCT06732531Phase 1, Phase 26 sites๐Ÿ“ Beijing๐Ÿ“ Xiamen๐Ÿ“ Changsha Zhuhai Beihai Biotech Co., Ltd ยท Tests: BH011 Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome NCT04047641Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cladribine, Cytarabine, Idarubicin, Quizartinib CC-99282 + Rituximab Early Post CART for Non-Hodgkin's Lymphoma NCT06209619Phase 11 site๐Ÿ“ Columbus Nathan Denlinger ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Golcadomide, Positron Emission Tomography Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome NCT03661307Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Decitabine, Quizartinib, Venetoclax Evaluation of EXL01, a New Live Biotherapeutic Product to Prevent Recurrence of Clostridioides Difficile Infection in High-risk Patients NCT06306014Phase 1, Phase 210 sites๐Ÿ“ Annecy๐Ÿ“ Clermont-Ferrand๐Ÿ“ Grenoble Hospices Civils de Lyon ยท Tests: EXL01, EXL01, Placebo Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy NCT07000084Phase 360 sites๐Ÿ“ Birmingham๐Ÿ“ Fairbanks๐Ÿ“ Gilbert Alliance for Clinical Trials in Oncology ยท Tests: BCG Solution, Biopsy of Bladder, Cystoscopy, Computed Tomography, Magnetic Resonance Imaging Venetoclax Basket Trial for High Risk Hematologic Malignancies NCT05292664Phase 15 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Atlanta Andrew E. Place, MD ยท Tests: Venetoclax, Azacitidine, Cytarabine, Methotrexate, Hydrocortisone Exploring the Efficacy and Safety of Tislelizumab in Combination With S-1 in the Treatment of Patients With Postoperative Recurrent High-risk Intrahepatic Cholangiocarcinoma NCT06664021Phase 22 sites๐Ÿ“ Fuyang๐Ÿ“ Hefei Anhui Provincial Hospital ยท Tests: Tislelizumab combined with S-1 Study in Children and Adolescents of 177Lu-DOTATATE (Lutatheraยฎ) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site๐Ÿ“ Boadilla del Monte Fundaciรณn de investigaciรณn HM ยท Tests: Olaparib; 177Lu-DOTATATE Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252 NCT06126744Phase 12 sites๐Ÿ“ New York๐Ÿ“ Durham Duke University ยท Tests: MVR-C5252 A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma NCT07464925Phase 13 sites๐Ÿ“ Tampa๐Ÿ“ Chicago๐Ÿ“ New York Tetragon Biosciences Ltd ยท Tests: GLIX1 Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia NCT03418038Phase 24 sites๐Ÿ“ Mankato๐Ÿ“ Rochester๐Ÿ“ Eau Claire Mayo Clinic ยท Tests: Ascorbic Acid, Carboplatin, Cisplatin, Cytarabine, Dexamethasone A Clinical Trial Evaluating the Tolerability, Safety, and Preliminary Efficacy of NRG-103 Injection in Patients With Recurrent or Progressive High-grade Glioma NCT07710690Phase 13 sites๐Ÿ“ Shanghai๐Ÿ“ Wuhan๐Ÿ“ Xi'an Neuregen Therapeutics Co., Ltd. ยท Tests: NRG-103
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