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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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12 recruiting trials

for High-risk Muscle Invasive Urothelial Carcinoma

Is Prolonged Systemic Immunotherapy Necessary After Achieving Tumor-free Status in Patients With Extensive Transurethrally Unresectable Very-high-risk NMIBC? NCT07625527Phase 24 sites📍 Tianjin📍 Tianjin📍 Tianjin Tianjin Medical University Second Hospital · Tests: Active Surveillance, PD-1/PD-L1 Inhibitor-Based Systemic Immunotherapy Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors NCT06493552Phase 2, Phase 31 site📍 Santa Monica Vasgene Therapeutics, Inc · Tests: SEphB4-HSA, Pembrolizumab, Gemcitabine, Cisplatin, Enfortumab vedotin EV + Toripalimab vs GC as Neoadjuvant Therapy in Locally Advanced/High-Risk MIBC NCT07647289Phase 21 site📍 Beijing Peking University Third Hospital · Tests: enfortumab vedotin (EV), Toripalimab, Gemcitabine (Chemotherapy), Cisplatin Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC NCT07322263Phase 21 site📍 Iowa City Michael A. O'Donnell · Tests: Intravesical Gemcitabine and Docetaxel Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer NCT07480356Phase 311 sites📍 Queen Creek📍 Little Rock📍 Bakersfield Protara Therapeutics · Tests: TARA-002, Investigator's Choice of Intravesical Chemotherapy Evaluating Safety and Efficacy of Verity-BCG in BCG-naïve Patients With Intermediate and High-risk Non-muscle Invasive Bladder (NMIBC) NCT05037279Phase 36 sites📍 Vancouver📍 Kingston📍 Toronto Verity Pharmaceuticals Inc. · Tests: Bacillus Calmette-Guerin: Strain Russian BCG-I, Bacillus Calmette-Guerin: Strain TICE An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC NCT07720284Phase 3160 sites📍 Hot Springs📍 Little Rock📍 Little Rock AstraZeneca · Tests: Dato-DXd, Rilvegostomig, Durvalumab, Nivolumab, Pembrolizumab Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma at High-Risk Recurrence NCT06682728Phase 21 site📍 Orange University of California, Irvine · Tests: Sacituzumab Govitecan (SG), Nivolumab Vesical Imaging-Reporting and Data System (VI-RADS) Followed by Photodynamic Trans-urethral Resection of Bladder Tumours (PDD-TURBT) to Avoid Secondary Resections (Re-TURBT) in Non-Muscle Invasive Bladder Cancers (NMIBCs) NCT05962541Phase 41 site📍 Rome University of Roma La Sapienza · Tests: PDD-TURBT with hexaminolevulinate (Hexvix®), Power Led Saphira (TM) DV+BCG in HER2-Expressing, BCG-Naïve High-Risk NMIBC NCT07207824Phase 31 site📍 Shanghai Fudan University · Tests: Active Comparator: BCG induction and maintenance, DV + BCG induction and maintenance Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial NCT06770582Phase 2147 sites📍 Tucson📍 Fayetteville📍 Rogers National Cancer Institute (NCI) · Tests: Biospecimen Collection, Cisplatin, Computed Tomography, Fluorouracil, Gemcitabine A Multicenter Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD) NCT06991868n/a1 site📍 Beijing Peking University First Hospital
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