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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for High-risk Neuroblastoma

Study in Children and Adolescents of 177Lu-DOTATATE (Lutatheraยฎ) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site๐Ÿ“ Boadilla del Monte Fundaciรณn de investigaciรณn HM ยท Tests: Olaparib; 177Lu-DOTATATE Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma NCT06172296Phase 3180 sites๐Ÿ“ Birmingham๐Ÿ“ Mobile๐Ÿ“ Mesa National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Carboplatin, Cisplatin A Study of a Vaccine in Combination With ฮฒ-glucan and GM-CSF in People With Neuroblastoma NCT04936529Phase 21 site๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: ฮฒ-glucan, GM-CSF, OPT-821 Immunotherapy With Dinutuximab Beta in Combination With Chemotherapy for the Treatment of Patients With Primary Neuroblastoma Refractory to Standard Therapy and With Relapsed or Progressive Disease NCT05272371Phase 11 site๐Ÿ“ Krakow Jagiellonian University ยท Tests: Chemoimmunotherapy (Dinutuximab beta in combination with chemotherapy) Phase I Study of Umbilical Cord Blood Natural Killer (NK) Cell Therapy for Children With High-risk, R/R Neuroblastoma. NCT06631391Phase 12 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: umbilical cord blood NK cells Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation NCT06942039EARLY Phase 112 sites๐Ÿ“ Calgary๐Ÿ“ Vancouver๐Ÿ“ Winnipeg C17 Council ยท Tests: Cytarabine IT, hydrocortisone, Cisplatin, Vincristine, Etoposide High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN) NCT04221035Phase 3142 sites๐Ÿ“ Sydney๐Ÿ“ Clayton๐Ÿ“ Nedlands Gustave Roussy, Cancer Campus, Grand Paris ยท Tests: Vincristine, Carboplatin, Etoposide, Vindesine, Dacarbazine A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma NCT06057948Phase 27 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: OPT-821 (QS-21), oral ฮฒ-glucan Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma NCT05489887Phase 226 sites๐Ÿ“ Birmingham๐Ÿ“ Little Rock๐Ÿ“ Oakland Giselle Sholler ยท Tests: Naxitamab Dinutuximab-beta and Chemotherapy in Newly Diagnosed High-Risk Neuroblastoma NCT07688252Phase 12 sites๐Ÿ“ Taipei๐Ÿ“ Taoyuan Chang Gung Memorial Hospital ยท Tests: Dinutuximab Beta, Induction chemotherapy Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma NCT02605421Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Thiotepa, Cyclophosphamide, Melphalan, Etoposide, Carboplatin 177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-risk Neuroblastoma NCT04903899Phase 25 sites๐Ÿ“ Copenhagen๐Ÿ“ Vilnius๐Ÿ“ Utrecht Jakob Stenman ยท Tests: 177Lu-DOTATATE Dual-Target GD2/B7-H3 CAR-NK Cells for Pediatric Relapsed or Refractory Neuroblastoma NCT07502287Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-DTNB-NK, Fludarabine, Cyclophosphamide Reduced Intensity Haploidentical BMT for High Risk Solid Tumors NCT01804634Phase 23 sites๐Ÿ“ Baltimore๐Ÿ“ The Bronx๐Ÿ“ Valhalla Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Cyclophosphamide, Fludarabine, low dose total body irradiation, Melphalan, Tacrolimus Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma NCT06831552NA6 sites๐Ÿ“ Hartford๐Ÿ“ Atlanta๐Ÿ“ Boston Dana-Farber Cancer Institute ยท Tests: RISE Intervention Chemoimmunotherapy Combined With Autologous NK Cell Therapy for Pediatric Patients With Refractory and Relapsed High-Risk Neuroblastoma and Ganglioneuroblastoma NCT07375563Phase 31 site๐Ÿ“ Moscow Federal Research Institute of Pediatric Hematology, Oncologโ€ฆ ยท Tests: Dinutuximab beta, temozolomide, irinotecan, autologous NK cell, irinotecan, temozolomide, dinutuximab beta, NK-cell proโ€ฆ Study Combining Dinutuximab Beta With Two Chemotherapy Regimens in Neuroblastoma NCT06485947Phase 11 site๐Ÿ“ Utrecht Princess Maxima Center for Pediatric Oncology ยท Tests: Dinutuximab beta, chemotherapy treatment called GPOH, chemotherapy treatment called rapid COJEC A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors NCT05135975Phase 26 sites๐Ÿ“ Birmingham๐Ÿ“ Aurora๐Ÿ“ Washington D.C. Nationwide Children's Hospital ยท Tests: Cabozantinib N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma NCT06528496Phase 21 site๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: DANYELZA, Sargramostim, Cytoxan, Topotecan, Vincristine Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL) NCT03126916Phase 3164 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ Little Rock Children's Oncology Group ยท Tests: Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspiration and Biopsy, Busulfanโ€ฆ Safety and Efficacy of Systemic Allogenic NK Cells in R/R Neuroblastoma NCT06674265Phase 11 site๐Ÿ“ Tehran Marzieh Ebrahimi ยท Tests: Allogenic NK cells infusion Patients Between the Ages of 12 Months to 21 Years With Newly-Diagnosed High-Risk Neuroblastoma Will Receive Children's Oncology Group (COG) Type Recommended Therapy With the Addition of Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) to Induction Cycles 1-5 NCT07537400Phase 21 site๐Ÿ“ Jerusalem Shaare Zedek Medical Center ยท Tests: Naxitamab Induction Chemoimmunotherapy for Patients With High-risk Neuroblastoma NCT06071897Phase 31 site๐Ÿ“ Moscow Federal Research Institute of Pediatric Hematology, Oncologโ€ฆ ยท Tests: monoclonal antibodies GD2 Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors NCT06814496Phase 1, Phase 23 sites๐Ÿ“ Gilbert๐Ÿ“ Tucson๐Ÿ“ Seattle University of Arizona ยท Tests: Tarlatamab, Concurrent Radiation Therapy, Sequential Radiation therapy Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors NCT02508038Phase 11 site๐Ÿ“ Madison University of Wisconsin, Madison ยท Tests: TCRฮฑฮฒ+/CD19+ depleted Haploidentical HSCT, Zoledronate A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients NCT07549321Phase 2, Phase 318 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Chicago Renaissance Pharma Ltd. ยท Tests: hu1418K322A + Temozolomide + Irinotecan Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma NCT06803875Phase 1, Phase 22 sites๐Ÿ“ Boston๐Ÿ“ Boston Roberto Chiarle ยท Tests: Autologous hALK.CAR T cells Pediatric Precision Laboratory Advanced Neuroblastoma Therapy NCT02559778Phase 228 sites๐Ÿ“ Birmingham๐Ÿ“ Little Rock๐Ÿ“ Oakland Giselle Sholler ยท Tests: Ceritinib, dasatinib, sorafenib, vorinostat, DFMO Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastoma NCT06013618Phase 21 site๐Ÿ“ Guangzhou Sun Yat-Sen University Cancer Center ยท Tests: Naxitamab monotherapy, GM-CSF, Irinotecan, Temozolomide, Naxitamab in combination therapy Adding Of Naxitamb In Induction Therapy For High Risk Neuroblastoma NCT06574698n/a1 site๐Ÿ“ Guanzhou Guangzhou Women and Children's Medical Center ยท Tests: Addition of anti-GD2 immunotherapy (Naxitamab) at the stage of induction chemotherapy
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