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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Hypopharyngeal Cancer

A Machine Learning-Based Risk Prediction Model for Head and Neck Cancerous Lesions NCT07532538n/a1 site๐Ÿ“ Nanjing The Affiliated Nanjing Drum Tower Hospital of Nanjing Univeโ€ฆ Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome NCT06380686n/a2 sites๐Ÿ“ Essen๐Ÿ“ Hanover AIO-Studien-gGmbH ยท Tests: data collection Immune Biomarker Study for Cisplatin-ineligible Patients Receiving Chemoradiotherapy With Docetaxel NCT06947668n/a1 site๐Ÿ“ Erlangen University of Erlangen-Nรผrnberg Medical School Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites๐Ÿ“ Tampa๐Ÿ“ Chicago๐Ÿ“ Fairway National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Resโ€ฆ Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: SX-682, DTX Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population NCT06997068Phase 21 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Celecoxib, Erlotinib Hydrochloride, Imaging Procedure, Interview, Methotrexate Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site๐Ÿ“ Rotterdam Erasmus Medical Center ยท Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants NCT00898638n/a4 sites๐Ÿ“ Nashville๐Ÿ“ Nashville๐Ÿ“ Nashville Vanderbilt University Medical Center ยท Tests: biologic sample preservation procedure, medical chart review Neoadjuvant PD-1 Inhibitor Combined With Cetuximab and Platinum in Resectable Locally Advanced Hypopharyngeal Carcinoma NCT06151743Phase 21 site๐Ÿ“ Shanghai Eye & ENT Hospital of Fudan University ยท Tests: three cycles (toripalimab + cetuximab + platinum), Radical surgery, Radiotherapy or chemoradiotherapy Use of SPY Imaging System to Minimize Fistulas After Hypopharyngeal Reconstruction NCT06831149Phase 21 site๐Ÿ“ Pittsburgh Matthew Spector ยท Tests: Removal of pharyngeal mucosa with decreased perfusion will be performed, SPY-PHI, ICG (Indocyanine Green) Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Irvine National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography The Management of Metastatic Neck Nodes in N2/3 Hypopharyngeal Squamous Cell Carcinoma NCT05494190NA3 sites๐Ÿ“ Harbin๐Ÿ“ Jinan๐Ÿ“ Shanghai Eye & ENT Hospital of Fudan University ยท Tests: Docetaxel, Cisplatin, Capecitabine, Concomitant chemoradiotherapy, Surgery Window of Opportunity in Preserving Laryngeal Function Trial NCT07423078Phase 21 site๐Ÿ“ Pittsburgh Matthew Spector ยท Tests: Toripalimab, Carboplatin, Cisplatin, Paclitaxel, Radiation Therapy The Voice as a Tool to Detect Recurrence of Laryngeal and Hypopharyngeal Cancer NCT05894070n/a2 sites๐Ÿ“ Bern๐Ÿ“ Zurich Insel Gruppe AG, University Hospital Bern ยท Tests: Voice recording, ENT (Ear, Nose and Throat) examination including transnasal fiberendoscopy, and VHI-30-questionnaire Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers NCT00900419n/a1 site๐Ÿ“ Aurora University of Colorado, Denver ยท Tests: immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology, biopsy Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients" NCT01365169NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Exercise Intervention, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] NCT06137378Phase 29 sites๐Ÿ“ Mannheim๐Ÿ“ Ulm๐Ÿ“ Mรผnchen University of Leipzig ยท Tests: KEYTRUDAยฎ A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC NCT07807163Phase 27 sites๐Ÿ“ Fort Myers๐Ÿ“ Orlando๐Ÿ“ St. Petersburg Bicara Therapeutics ยท Tests: Ficerafusp alfa, Pembrolizumab (KEYTRUDAยฎ) Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer NCT06532279Phase 2153 sites๐Ÿ“ Gilbert๐Ÿ“ Peoria๐Ÿ“ Phoenix NRG Oncology ยท Tests: Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy Integrated Cancer Repository for Cancer Research NCT02012699n/a42 sites๐Ÿ“ Greenwood Village๐Ÿ“ Manchester๐Ÿ“ Daytona Beach University of Nebraska Submental Flap for the Reconstruction of Hypopharyngectomy NCT06161779NA1 site๐Ÿ“ Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ยท Tests: Surgical reconstruction Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) NCT06648096Phase 1, Phase 22 sites๐Ÿ“ Hanover๐Ÿ“ Barcelona Fundaciรณ Institut de Recerca de l'Hospital de la Santa Creuโ€ฆ ยท Tests: Afatinib Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytrudaยฎ) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) NCT04198766Phase 1, Phase 242 sites๐Ÿ“ Duarte๐Ÿ“ Glendale๐Ÿ“ Los Angeles Inhibrx Biosciences, Inc ยท Tests: INBRX-106 - Hexavalent OX40 agonist antibody, pembrolizumab 200 mg, pembrolizumab 400 mg, Carboplatin AUC-5, Carboplatiโ€ฆ Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer NCT06980038Phase 212 sites๐Ÿ“ Irvine๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles National Cancer Institute (NCI) ยท Tests: Anti-CD40 Agonist Monoclonal Antibody CDX-1140, Biopsy Procedure, Biospecimen Collection, Cemiplimab, Computed Tomograpโ€ฆ Clinical Treatments in Specialized Diseases of Laryngeal Carcinoma (LC) and Hypopharyngeal Carcinoma (HPC) NCT04908696n/a1 site๐Ÿ“ Shanghai Eye & ENT Hospital of Fudan University ยท Tests: routines Intraoperative Methadone for the Management of Postoperative Pain in Patients With Head and Neck Cancers NCT07857655Phase 41 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Electronic Health Record Review, Fentanyl, Laryngoscopy, Methadone, Surgical Procedure Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery NCT02734537Phase 2679 sites๐Ÿ“ Birmingham๐Ÿ“ Anchorage๐Ÿ“ Anchorage ECOG-ACRIN Cancer Research Group ยท Tests: Cisplatin, Intensity-Modulated Radiation Therapy, Laboratory Biomarker Analysis Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia NCT07359586n/a2 sites๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou Zhejiang University Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma NCT07156227Phase 13 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ Pittsburgh National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Camonsertib, Computed Tomography, Positron Emission Tomography, Stereotactic Body Radiation Theโ€ฆ
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