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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Hypopharyngeal Squamous Cell Carcinoma

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome NCT06380686n/a2 sites📍 Essen📍 Hanover AIO-Studien-gGmbH · Tests: data collection Immune Biomarker Study for Cisplatin-ineligible Patients Receiving Chemoradiotherapy With Docetaxel NCT06947668n/a1 site📍 Erlangen University of Erlangen-Nürnberg Medical School Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites📍 Tampa📍 Chicago📍 Fairway National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites📍 Atlanta📍 Atlanta Emory University · Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Res… Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: SX-682, DTX Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site📍 Rotterdam Erasmus Medical Center · Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants NCT00898638n/a4 sites📍 Nashville📍 Nashville📍 Nashville Vanderbilt University Medical Center · Tests: biologic sample preservation procedure, medical chart review Use of SPY Imaging System to Minimize Fistulas After Hypopharyngeal Reconstruction NCT06831149Phase 21 site📍 Pittsburgh Matthew Spector · Tests: Removal of pharyngeal mucosa with decreased perfusion will be performed, SPY-PHI, ICG (Indocyanine Green) Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites📍 Tucson📍 Tucson📍 Irvine National Cancer Institute (NCI) · Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography The Management of Metastatic Neck Nodes in N2/3 Hypopharyngeal Squamous Cell Carcinoma NCT05494190NA3 sites📍 Harbin📍 Jinan📍 Shanghai Eye & ENT Hospital of Fudan University · Tests: Docetaxel, Cisplatin, Capecitabine, Concomitant chemoradiotherapy, Surgery Window of Opportunity in Preserving Laryngeal Function Trial NCT07423078Phase 21 site📍 Pittsburgh Matthew Spector · Tests: Toripalimab, Carboplatin, Cisplatin, Paclitaxel, Radiation Therapy Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers NCT00900419n/a1 site📍 Aurora University of Colorado, Denver · Tests: immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology, biopsy European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] NCT06137378Phase 29 sites📍 Mannheim📍 Ulm📍 München University of Leipzig · Tests: KEYTRUDA® A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC NCT07807163Phase 27 sites📍 Fort Myers📍 Orlando📍 St. Petersburg Bicara Therapeutics · Tests: Ficerafusp alfa, Pembrolizumab (KEYTRUDA®) Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer NCT06532279Phase 2153 sites📍 Gilbert📍 Peoria📍 Phoenix NRG Oncology · Tests: Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) NCT06648096Phase 1, Phase 22 sites📍 Hanover📍 Barcelona Fundació Institut de Recerca de l'Hospital de la Santa Creu… · Tests: Afatinib Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) NCT04198766Phase 1, Phase 242 sites📍 Duarte📍 Glendale📍 Los Angeles Inhibrx Biosciences, Inc · Tests: INBRX-106 - Hexavalent OX40 agonist antibody, pembrolizumab 200 mg, pembrolizumab 400 mg, Carboplatin AUC-5, Carboplati… Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer NCT06980038Phase 212 sites📍 Irvine📍 Los Angeles📍 Los Angeles National Cancer Institute (NCI) · Tests: Anti-CD40 Agonist Monoclonal Antibody CDX-1140, Biopsy Procedure, Biospecimen Collection, Cemiplimab, Computed Tomograp… Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery NCT02734537Phase 2679 sites📍 Birmingham📍 Anchorage📍 Anchorage ECOG-ACRIN Cancer Research Group · Tests: Cisplatin, Intensity-Modulated Radiation Therapy, Laboratory Biomarker Analysis Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma NCT07156227Phase 13 sites📍 Duarte📍 Irvine📍 Pittsburgh National Cancer Institute (NCI) · Tests: Biospecimen Collection, Camonsertib, Computed Tomography, Positron Emission Tomography, Stereotactic Body Radiation The… Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation NCT06662058NA1 site📍 Atlanta Emory University · Tests: Audiometric Test, Audiometric Test, Audiometric Test, Interview Neoadjuvant EGFR-ADC Combined With Anti-PD-1 Monoclonal Antibody in Resectable Locally Advanced Hypopharyngeal Squamous Cell Carcinoma NCT07665190Phase 21 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: Becotatug Vedotin and Pucotenlimab Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial NCT06636734Phase 22 sites📍 Atlanta📍 Atlanta Emory University · Tests: Biospecimen Collection, Computed Tomography, Lovastatin, Magnetic Resonance Imaging, Pembrolizumab Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment NCT06589804Phase 3202 sites📍 Little Rock📍 Marysville📍 Palo Alto National Cancer Institute (NCI) · Tests: Biospecimen Collection, Cetuximab, Computed Tomography, Magnetic Resonance Imaging, Pembrolizumab 5-Fluorouracil Response and Optimization STudy (The FROST Trial) NCT07419464Phase 21 site📍 St Louis Washington University School of Medicine · Tests: 5-Fluorouracil Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy NCT05337631n/a18 sites📍 Baltimore📍 New York📍 Cleveland University Hospital Freiburg Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer NCT06914999EARLY Phase 11 site📍 Atlanta Emory University · Tests: Computed Tomography, Fludeoxyglucose F-18, Intensity-Modulated Proton Therapy, Intensity-Modulated Radiation Therapy, P… Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer NCT07058805Phase 23 sites📍 Basel📍 Bern📍 Zurich Olgun Elicin · Tests: Compartmentalized Postoperative Radiotherapy BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study NCT05136196Phase 2232 sites📍 Phoenix📍 Little Rock📍 Beverly Hills National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate, Computed Tomography, Magnetic Resonance Imaging Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck NCT01473784NA1 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: transoral robotic surgery, quality of life assessment
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