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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Idiopathic Inflammatory Myopathy (IIM)

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) NCT06350110Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: CD19- BCMA CAR-T cells Adult and Juvenile Myositis NCT00017914n/a4 sites๐Ÿ“ Atlanta๐Ÿ“ Bethesda๐Ÿ“ Research Triangle Park National Institute of Environmental Health Sciences (NIEHS) CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C) in Patients With Relapse/Refractory Autoimmune Diseases NCT07315087Phase 11 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: QT-019C An Exploratory Study of CD19/CD22/BCMA CAR-T Cells (BZE2204) in Subjects With Relapsed or Refractory Autoimmune Diseases NCT07174843EARLY Phase 11 site๐Ÿ“ Shanghai Shanghai Cell Therapy Group Co.,Ltd ยท Tests: CD19/CD22/BCMA CAR-T cells(BZE2204) A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2) NCT06733935Phase 1, Phase 218 sites๐Ÿ“ Orange๐Ÿ“ Gainesville๐Ÿ“ Miami Nkarta, Inc. ยท Tests: NKX019, Fludarabine, Cyclophosphamide Safety and Efficacy of ULSC on Disease Severity and Steroid Tapering in Participants With Dermatomyositis/ Polymyositis (DM/PM), Also Known as Idiopathic Inflammatory Myopathy (IIM) NCT07160205Phase 2, Phase 32 sites๐Ÿ“ Gainesville๐Ÿ“ Miami Restem, LLC. ยท Tests: ULSC (1.5 x 10^8 cells/dose), Placebo (no cells) Optimizing Treatment on Idiopathic Inflammatory Myopathies NCT03092180n/a1 site๐Ÿ“ Sรฃo Paulo University of Sao Paulo ยท Tests: Intravenous Infusion A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic Inflammatory Myopathies NCT06698796Phase 326 sites๐Ÿ“ Glendale๐Ÿ“ Frisco๐Ÿ“ Houston Pfizer ยท Tests: Dazukibart Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases NCT07085676Phase 11 site๐Ÿ“ Jerusalem Polina Stepensky ยท Tests: HBI0101 CART GC012F Injection in Refractory Idiopathic Inflammatory Myopathy NCT07086404EARLY Phase 11 site๐Ÿ“ Wuhan Daishi Tian ยท Tests: GC012F Injection infusion A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis) NCT06455449Phase 3237 sites๐Ÿ“ Phoenix๐Ÿ“ Irvine๐Ÿ“ Aurora AstraZeneca ยท Tests: Anifrolumab (blinded), Placebo, Anifrolumab (unblinded, open label) AlloNKยฎ, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases. NCT06991114Phase 252 sites๐Ÿ“ Tuscaloosa๐Ÿ“ Phoenix๐Ÿ“ Tucson Artiva Biotherapeutics, Inc. ยท Tests: Allogeneic NK Cells A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease NCT06308978Phase 121 sites๐Ÿ“ Beverly Hills๐Ÿ“ Fullerton๐Ÿ“ Irvine Fate Therapeutics ยท Tests: FT819, Fludarabine, Cyclophosphamide, Bendamustine A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases NCT07115745Phase 128 sites๐Ÿ“ Boston๐Ÿ“ Durham๐Ÿ“ Camperdown Juno Therapeutics, Inc., a Bristol-Myers Squibb Company ยท Tests: BMS-986515, Fludarabine, Cyclophosphamide, Tocilizumab A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)] NCT05895786Phase 3138 sites๐Ÿ“ Glendale๐Ÿ“ Phoenix๐Ÿ“ Phoenix Pfizer ยท Tests: PF-06823859, Placebo A Study of AZD0120 in Autoimmune Diseases NCT07295847Phase 122 sites๐Ÿ“ Tucson๐Ÿ“ Stanford๐Ÿ“ Chicago AstraZeneca ยท Tests: AZD0120 A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease NCT06925542Phase 117 sites๐Ÿ“ La Jolla๐Ÿ“ Redwood City๐Ÿ“ Chicago CRISPR Therapeutics ยท Tests: CTX112 A Study of OL-108 in Relapsed/Refractory Autoimmune Diseases NCT06980597Phase 12 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Beijing GoBroad Hospital ยท Tests: OL-108 A Study of CC312 for Relapsed/Refractory Autoimmune Diseases NCT07193810EARLY Phase 11 site๐Ÿ“ Deyang CytoCares Inc ยท Tests: CC312 Safety Study of CC312 in Autoimmune Disease Patients NCT06888960EARLY Phase 11 site๐Ÿ“ Tianjin CytoCares Inc ยท Tests: CC312 A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease NCT07085104Phase 117 sites๐Ÿ“ Phoenix๐Ÿ“ Loma Linda๐Ÿ“ Aurora Allogene Therapeutics ยท Tests: ALLO-329, Cyclophosphamide, Fludarabine Adult Autoimmune Myopathies (MAIA) NCT04792931NA1 site๐Ÿ“ Brest University Hospital, Brest ยท Tests: description of adult autoimmune myopathies Follow-up of Patients With Inflammatory Myopathies Associated With a Biobank NCT05454527n/a2 sites๐Ÿ“ Paris๐Ÿ“ Paris Assistance Publique - Hรดpitaux de Paris Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases NCT07087912Phase 42 sites๐Ÿ“ Sรฃo Paulo๐Ÿ“ Sรฃo Paulo University of Sao Paulo General Hospital ยท Tests: Dengue 1,2,3,4 (attenuated) vaccine Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases NCT06548607EARLY Phase 11 site๐Ÿ“ Bengbu Nanjing Bioheng Biotech Co., Ltd. ยท Tests: CD19 or CD19-BCMA CAR-T Ublituximab in Autoantibody Positive Immune Mediated Necrotizing Myopathy NCT07103746Phase 28 sites๐Ÿ“ Birmingham๐Ÿ“ Atlanta๐Ÿ“ Chicago National Institute of Allergy and Infectious Diseases (NIAIโ€ฆ ยท Tests: Ublituximab, Placebo for Ublituximab OM336 in Seropositive Autoimmune Diseases NCT07229144Phase 11 site๐Ÿ“ Hamilton Lakefront Biotherapeutics West LLC ยท Tests: OM336 Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Patients With Sporadic Inclusion Body Myositis NCT06479863EARLY Phase 12 sites๐Ÿ“ Austin๐Ÿ“ Austin Austin Neuromuscular Center ยท Tests: Pozelimab/Cemdisiran FT839 in Autoimmune Diseases NCT07800871Phase 1, Phase 21 site๐Ÿ“ Fullerton Fate Therapeutics ยท Tests: FT839 Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases NCT06285539Phase 26 sites๐Ÿ“ Amsterdam๐Ÿ“ Heerlen๐Ÿ“ Nijmegen UMC Utrecht ยท Tests: Filgotinib
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