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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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23 recruiting trials

for Impaired Hepatic Function

Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment NCT07036133Phase 14 sites📍 Cerritos📍 Chicago📍 Detroit Acrotech Biopharma Inc. · Tests: Pralatrexate Injection A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With and Without Reduced Liver Function NCT07269301Phase 13 sites📍 Lake Forest📍 Orlando📍 Tampa Pfizer · Tests: PF-07328948 A Phase I Clinical Trial to Evaluate the Pharmacokinetic and Safety of Ammoxetine Hydrochloride Enteric-Coated Tablets in Participants With Mild Hepatic Impairment, Moderate Hepatic Impairment, and Normal Liver Function NCT07694843Phase 11 site📍 Suzhou CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · Tests: ammoxetine hydrochloride enteric-coated tablets A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers. NCT07401862Phase 13 sites📍 Orlando📍 San Antonio📍 Kistarcsa Eli Lilly and Company · Tests: LY3841136 Comparative PK Assessment Study of Casdatifan in Moderate Hepatically Impaired Participants Versus Matched Participants With Normal Hepatic Function NCT07751250Phase 11 site📍 San Antonio Arcus Biosciences, Inc. · Tests: Casdatifan A Study to Learn About the Medicine Called PF-08653944 in People With and Without Reduced Liver Function NCT07519135Phase 13 sites📍 Miami Lakes📍 Orlando📍 Tampa Pfizer · Tests: PF-08653944 Pharmacokinetics of Petrelintide in Participants With Impaired Hepatic Function NCT07682818Phase 13 sites📍 Wroclaw📍 Bratislava📍 Malacky Zealand Pharma · Tests: Petrelintide Pharmacokinetic Study of Vorasidenib in Severe Hepatically Impaired and Matched-Control Participants NCT07250633Phase 13 sites📍 Chandler📍 Orlando📍 San Antonio Institut de Recherches Internationales Servier (I.R.I.S.) · Tests: Vorasidenib 20mg Assessment of Quizartinib Pharmacokinetic in Subjects With Severe Hepatic Impairment NCT06740799Phase 13 sites📍 Miami📍 Miami📍 St. Petersburg Daiichi Sankyo · Tests: Quizartinib A Study of the Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment NCT07165002Phase 13 sites📍 Kistarcsa📍 Auckland📍 Bratislava Eli Lilly and Company · Tests: LY3537031 A Study to Learn How the Body Processes the Study Medicine Called Vepdegestrant in People With Loss of Liver Function NCT07231991Phase 14 sites📍 Miami📍 Miami Lakes📍 Orlando Pfizer · Tests: vepdegestrant A Trial to Examine if Repinatrabit is Processed Differently in Adults With Reduced Liver or Kidney Function Compared to Adults With Normal Liver and Kidney Function NCT07713758Phase 11 site📍 Miami Otsuka Pharmaceutical Development & Commercialization, Inc. · Tests: Repinatrabit A Study of HDM1002 in Subjects With And Without Varying Degrees Of Hepatic Impairement NCT06985615Phase 11 site📍 Suzhou Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. · Tests: Single dose of HDM1002 on Day 1 Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib NCT06997276Phase 13 sites📍 Miami📍 Orlando📍 San Antonio SpringWorks Therapeutics, Inc., a healthcare company of Mer… · Tests: Mirdametinib (MEK Inhibitor) A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of HS-10506 NCT07844967Phase 11 site📍 Hefei Jiangsu Hansoh Pharmaceutical Co., Ltd. · Tests: HS-10506 Pharmacokinetic Study of Vorolanib Tablets in Trial Participants With Hepatic Impairment NCT07809802Phase 11 site📍 Changchun Betta Pharmaceuticals Co., Ltd. · Tests: vorolanib, vorolanib, Vorolanib Perioperative Analgesia With Erector Spinae Plane Block in Liver Transplant Recipients NCT06857331NA1 site📍 Kyiv Bogomolets National Medical University · Tests: Erector Spinae Plane Block using 0.2% ropivacaine Investigation of Pharmacokinetics,Safety,and Pharmacodynamics of HSK39297 in Subjects With Hepatic Impairment NCT07152288Phase 11 site📍 Beijing Haisco Pharmaceutical Group Co., Ltd. · Tests: HSK39297 tablets, HSK39297 tablets, HSK39297 tablets A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment NCT07643155Phase 14 sites📍 Lake Forest📍 San Dimas📍 Orlando Insmed Incorporated · Tests: Treprostinil Palmitil Inhalation Powder A Pharmacokinetic Study of D-2570 in Participants With Hepatic Impairment and Normal Hepatic Function NCT07715149Phase 11 site📍 Bengbu InventisBio Co., Ltd · Tests: D-2570 To Evaluate the Pharmacokinetics of Hemay005 Tablets in Subjects With Liver Damage NCT06376474Phase 11 site📍 Wuhan Ganzhou Hemay Pharmaceutical Co., Ltd · Tests: Hemay005 A Study to Learn How the Study Medicine Called Atirmociclib is Handled by the Body in People With Normal Liver Function and Different Levels of Liver Disease NCT07677358Phase 13 sites📍 Miami Lakes📍 Orlando📍 Tampa Pfizer · Tests: Atirmociclib A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment NCT07343960Phase 12 sites📍 Rialto📍 San Antonio AstraZeneca · Tests: Capivasertib
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