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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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21 recruiting trials

for Large B-Cell Lymphoma (LBCL)

Bendamustine Versus Fludarabine/Cyclophosphamide for Lymphodepletion in Chimeric Antigen Receptor T-cell Immunotherapy (CAR-T): a Randomized Trial. NCT07593482Phase 29 sites📍 Aarau📍 Basel📍 Bellinzona Swiss Cancer Institute · Tests: bendamustine hydrochloride, Cyclophosphamide, Fludarabine Linperlisib Combined With Immunochemotherapy in Relapsed/Refractory LBCL NCT06489808Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Linperlisib, Rituximab, Gemcitabine, Oxaliplatin, Ifosfamide CAR-T Combined With ASCT in the Treatment of Relapsed/Refractory Large B-cell Lymphoma With High-risk Factors. NCT07538635Phase 21 site📍 Hangzhou Zhejiang Cancer Hospital · Tests: Axicabtagene Ciloleucel Real World Practice With Academic Anti CD19 CAR-T Cell Therapy in Relapse/Refractory B-cell Lymphoma NCT07524816n/a1 site📍 Lyasny N.N. Alexandrov National Cancer Centre · Tests: CAR-T cell therapy Epcoritamab (Epcor)-Containing Combination Salvage Therapy Followed by ASCT & Epcor Consolidation in Patients With Relapsed LBCL NCT06287398Phase 21 site📍 Melbourne Australasian Leukaemia and Lymphoma Group · Tests: Epcoritamab Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma NCT06905509Phase 21 site📍 Sacramento University of California, Davis · Tests: Autologous Hematopoietic Stem Cell Transplantation, Carboplatin, Cytarabine, Dexamethasone, Epcoritamab AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL NCT07215585Phase 382 sites📍 Clayton📍 Macquarie University📍 Melbourne AstraZeneca · Tests: AZD0486, R-mini-CHOP A Phase I/II Trial of CT1190B in Patients With Relapsed/Refractory Large B-Cell Lymphoma NCT07823829Phase 1, Phase 23 sites📍 Shanghai📍 Shanghai📍 Hubei UCARsgen Biotech Limited · Tests: CT1190B intravenous infusion Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma NCT06830759n/a73 sites📍 Ciudad Autonoma de Buenos Aire📍 Pilar📍 Ciudad Autonoma de Buenos Aire AbbVie Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL NCT06104592Phase 21 site📍 Tampa H. Lee Moffitt Cancer Center and Research Institute · Tests: Comprehensive Ablative Bridging Irradiation (CABI), Chimeric Antigen Receptor T-Cell Therapy Investigator Initiated Study to Assess the Safety of Combination of CLS-015 With Anti-CD-19 CAR-T Cells in Patients With Stable/Progressive Large B Cell Lymphoma at Lymphodepletion. NCT07361224Phase 11 site📍 Tel Aviv Tel-Aviv Sourasky Medical Center · Tests: rhDNase I A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7×19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma NCT07788118Phase 1, Phase 21 site📍 Hangzhou Second Affiliated Hospital, Zhejiang University, School of … · Tests: 7×19-THEMIS CAR-T cells Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL NCT06526793Phase 294 sites📍 Phoenix📍 Duarte📍 Jacksonville AstraZeneca · Tests: Surovatamig A Phase II Study of Loncastuximab Tesirine as Consolidation Strategy in Patients With LBCL in PR After CAR T-cell Therapy NCT05464719Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Loncastuximab Tesirine CD19-targeted CAR T Cells for Relapsed or Refractory (R/R) Large B-cell Lymphoma NCT06479356Phase 21 site📍 Tianjin Shanghai Ming Ju Biotechnology Co., Ltd. · Tests: Relma-cel Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients NCT04844866Phase 251 sites📍 Graz📍 Innsbruck📍 Linz Miltenyi Biomedicine GmbH · Tests: MB-CART2019.1, Standard of Care Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL NCT06500273Phase 285 sites📍 Gilbert📍 Hot Springs📍 Berkeley Allogene Therapeutics · Tests: cemacabtagene ansegedleucel, Fludarabine, Cyclophosphamide, Foresight CLARITY™ IUO MRD test, powered by PhasED-Seq™ The Efficacy and Safety of Pola-ZR-Glo in Older Treatment-naive Patients With LBCL NCT07514169Phase 21 site📍 Shanghai Ruijin Hospital · Tests: Pola-ZR-Glo (Polatuzumab Vedotin, Zanubrutinib, Lenalidomide and Glofitamab) regimen The Efficacy and Safety of Glofitamab in Combination With PD-1 Antibody and Lenalidomide in Patients With Relapsed/Refractory Large B-cell Lymphoma (LBCL) With TP53 Aberrations: A Prospective, Multicenter, Phase II Clinical Study NCT07240194Phase 21 site📍 Nanjing The First Affiliated Hospital with Nanjing Medical Universi… · Tests: Glofitamab, PD-1 Inhibitor, Lenalidomide, Obinutuzumab CD19 CAR-T Therapy for Patients With Newly Diagnosed High-risk Large B-cell Lymphoma NCT04661020Phase 21 site📍 Hangzhou Zhejiang University · Tests: CD19 CAR-T cells A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies. NCT06542250Phase 1, Phase 231 sites📍 La Jolla📍 Boston📍 Rochester AstraZeneca · Tests: AZD5492
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