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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Laryngeal Squamous Cell Carcinoma

VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer NCT04057209NA4 sites📍 Paris📍 Mumbai📍 Bern Olgun Elicin · Tests: Single Vocal Cord Irradiation (SVCI), Arm A: Transoral CO2-Laser Microsurgical Cordectomy (TLM) Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome NCT06380686n/a2 sites📍 Essen📍 Hanover AIO-Studien-gGmbH · Tests: data collection Immune Biomarker Study for Cisplatin-ineligible Patients Receiving Chemoradiotherapy With Docetaxel NCT06947668n/a1 site📍 Erlangen University of Erlangen-Nürnberg Medical School Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy NCT05793151NA4 sites📍 St Louis📍 Durham📍 Charleston Medical University of South Carolina · Tests: ENDURE Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer NCT07180901NA1 site📍 Montreal Centre hospitalier de l'Université de Montréal (CHUM) · Tests: Proactive Risk-Based Optimization and Notifications for Treatment and Outcomes (PRONTO) Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites📍 Tampa📍 Chicago📍 Fairway National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib Intralesional Chemotherapy (IC): Cisplatin + Epinephrine NCT07392580Phase 21 site📍 Miami University of Miami · Tests: Cisplatin, Epinephrine injection, Laryngeal Biopsy, Endoscopic Surgery Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN) NCT07209189Phase 21 site📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Toripalimab + Chemotherapy, Toripalimab, Chemoradiotherapy or radiation TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites📍 Atlanta📍 Atlanta Emory University · Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Res… Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: SX-682, DTX Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site📍 Rotterdam Erasmus Medical Center · Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation RAPA-201 Therapy of Solid Tumors NCT05144698Phase 1, Phase 21 site📍 Hackensack Rapa Therapeutics LLC · Tests: RAPA-201 Rapamycin Resistant T Cells, Chemotherapy Prior to RAPA-201 Therapy, Pembrolizumab (PD-1 Blocking Antibody) Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants NCT00898638n/a4 sites📍 Nashville📍 Nashville📍 Nashville Vanderbilt University Medical Center · Tests: biologic sample preservation procedure, medical chart review Use of SPY Imaging System to Minimize Fistulas After Hypopharyngeal Reconstruction NCT06831149Phase 21 site📍 Pittsburgh Matthew Spector · Tests: Removal of pharyngeal mucosa with decreased perfusion will be performed, SPY-PHI, ICG (Indocyanine Green) Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites📍 Tucson📍 Tucson📍 Irvine National Cancer Institute (NCI) · Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography Window of Opportunity in Preserving Laryngeal Function Trial NCT07423078Phase 21 site📍 Pittsburgh Matthew Spector · Tests: Toripalimab, Carboplatin, Cisplatin, Paclitaxel, Radiation Therapy Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers NCT00900419n/a1 site📍 Aurora University of Colorado, Denver · Tests: immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology, biopsy European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] NCT06137378Phase 29 sites📍 Mannheim📍 Ulm📍 München University of Leipzig · Tests: KEYTRUDA® A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC NCT07807163Phase 27 sites📍 Fort Myers📍 Orlando📍 St. Petersburg Bicara Therapeutics · Tests: Ficerafusp alfa, Pembrolizumab (KEYTRUDA®) Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer NCT06532279Phase 2153 sites📍 Gilbert📍 Peoria📍 Phoenix NRG Oncology · Tests: Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) NCT06648096Phase 1, Phase 22 sites📍 Hanover📍 Barcelona Fundació Institut de Recerca de l'Hospital de la Santa Creu… · Tests: Afatinib Study Evaluating the Safety and Feasibility of Panitumumab-IRDye800 and [18F]NOTA-ABY-030 for Targeted Dual-Modality Imaging (TDMI) in Head and Neck Squamous Cell Carcinoma NCT07741643Phase 11 site📍 Nashville Vanderbilt-Ingram Cancer Center · Tests: Panitumumab-IRDye800, [18F]NOTA-ABY-030 Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer NCT06980038Phase 212 sites📍 Irvine📍 Los Angeles📍 Los Angeles National Cancer Institute (NCI) · Tests: Anti-CD40 Agonist Monoclonal Antibody CDX-1140, Biopsy Procedure, Biospecimen Collection, Cemiplimab, Computed Tomograp… High-Resolution PET-CT Imaging for Surgical Margin Visualization NCT06915454NA1 site📍 Nashville Vanderbilt-Ingram Cancer Center · Tests: Intra-op PET/CT Specimen Scanner Intraoral Hypothermia Device for Preserving Taste During Radiation NCT06579248EARLY Phase 11 site📍 Detroit Henry Ford Health System · Tests: Intraoral Device Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery NCT02734537Phase 2679 sites📍 Birmingham📍 Anchorage📍 Anchorage ECOG-ACRIN Cancer Research Group · Tests: Cisplatin, Intensity-Modulated Radiation Therapy, Laboratory Biomarker Analysis Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma NCT07156227Phase 13 sites📍 Duarte📍 Irvine📍 Pittsburgh National Cancer Institute (NCI) · Tests: Biospecimen Collection, Camonsertib, Computed Tomography, Positron Emission Tomography, Stereotactic Body Radiation The… Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer NCT03114462Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: Stereotactic Hypofractionated Radioablation, Questionnaires Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation NCT06662058NA1 site📍 Atlanta Emory University · Tests: Audiometric Test, Audiometric Test, Audiometric Test, Interview Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer NCT04754321Phase 11 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: External Beam Radiation Therapy, Intraoperative Radiation Therapy, Pembrolizumab, Quality-of-Life Assessment, Salvage S…
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