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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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14 recruiting trials

for Leptomeningeal Metastasis of Breast Cancer

Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Methotrexate in Breast Cancer With Leptomeningeal Metastasis NCT06543992Phase 21 site📍 Nanjing The First Affiliated Hospital with Nanjing Medical Universi… · Tests: Intrathecal Administration of Thiotepa in Combination with Methotrexate via the Ommaya Reservoir Study in Patients With Breast Cancer Leptomeningeal Metastasis NCT06638294n/a2 sites📍 Washington D.C.📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial NCT06500481Phase 358 sites📍 Phoenix📍 Little Rock📍 Encinitas NRG Oncology · Tests: Biospecimen Collection, Computed Tomography, Involved-Field Radiation Therapy, Lumbar Puncture, Magnetic Resonance Imag… Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer NCT06462092Phase 1, Phase 21 site📍 Huizhou Guangzhou Medical University · Tests: Sacituzumab Govitecan, Pemetrexed Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer NCT05746325NA1 site📍 Jacksonville Mayo Clinic · Tests: Digital Photography, Lumbar Puncture, Magnetic Resonance Imaging, Medical Device Usage and Evaluation, Biospecimen Coll… A Phase IIa Study to Evaluate NBQ72S NCT06810804Phase 21 site📍 Beijing Nantong Bencao Quadriga Medical Technology Co. Ltd. · Tests: NBQ72S Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer NCT06518057Phase 23 sites📍 San Francisco📍 New York📍 Seattle University of Washington · Tests: Biospecimen Collection, Computed Tomography, Electronic Health Record Review, Lumbar Puncture, Magnetic Resonance Imagi… Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer NCT06910761Phase 22 sites📍 Duarte📍 Irvine City of Hope Medical Center · Tests: Biospecimen Collection, Craniospinal Irradiation, Electronic Health Record Review, Lumbar Puncture, Magnetic Resonance … Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis NCT02422641Phase 23 sites📍 Baltimore📍 St Louis📍 Winston-Salem Wake Forest University Health Sciences · Tests: High-dose Methotrexate (8 gm/m2; HD-MTX) Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease NCT05800275Phase 211 sites📍 Bordeaux📍 Caen📍 Clermont-Ferrand UNICANCER · Tests: Tucatinib Oral Tablet, Capecitabine tablets, Trastuzumab Injection Phase I/II Study of Intrathecal/Ommaya T-DXd in HER2-Expressing Breast Cancer With Leptomeningeal/Brain Metastases NCT07134153Phase 1, Phase 22 sites📍 Shanghai📍 Shanghai Fudan University · Tests: T-DXd BRain-AVOidant Proton Craniospinal Irradiation for Leptomeningeal Metastases From Solid Tumor Malignancies NCT07789912NA1 site📍 Miami University of Miami · Tests: Radiation Treatments Using Brain- Avoidant Proton Craniospinal Irradiation (BRAVO- pCSI) Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis NCT06230055Phase 41 site📍 Shanghai Fudan University · Tests: Ommaya reservoir, Systematic chemotherapy, Intrathecal chemotherapy Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Trastuzumab in Breast Cancer With Leptomeningeal Metastasis NCT07263425Phase 21 site📍 Nanjing The First Affiliated Hospital with Nanjing Medical Universi… · Tests: Intrathecal Administration of Thiotepa in Combination with Trastuzumab via the Ommaya Reservoir
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