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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Locally Advanced Head and Neck Carcinoma

cDNA and Residual Disease After Chemoradiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinomas NCT07178847NA4 sites๐Ÿ“ Aurillac๐Ÿ“ Clermont-Ferrand๐Ÿ“ Lyon Centre Jean Perrin ยท Tests: blood sampling Adebrelimab ยฑInduction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC NCT06510660Phase 21 site๐Ÿ“ Fuzhou Fujian Medical University Union Hospital ยท Tests: adebrelimab Envafolimab Combined With Chemoradiotherapy and Recombinant Human Endostatin for LA-NPC. NCT06059261Phase 21 site๐Ÿ“ Chongqing Chongqing University Cancer Hospital ยท Tests: Envafolimab and recombinant human endostatin combined with chemoradiotherapy Neoadjuvant Adebrelimab Plus Chemotherapy for Esophageal Cancer: A Clinical Study NCT07437898Phase 21 site๐Ÿ“ Putian The Affiliated Hospital of Putian University ยท Tests: Adebrelimab, chemotherapy Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer NCT06173986Phase 1, Phase 21 site๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: PD-1inhibitor, nab-paclitaxel + cisplatin, Radiotherapy Nimotuzumab Combined With Immunotherapy and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma NCT07601737Phase 21 site๐Ÿ“ Shanghai Shanghai General Hospital, Shanghai Jiao Tong University Scโ€ฆ ยท Tests: Nimotuzumab Injection, Tislelizumab, Albumin-Bound Paclitaxel /nab-Paclitaxel, Cisplatin (Or Carboplatin), Radical surgโ€ฆ Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites๐Ÿ“ Tampa๐Ÿ“ Chicago๐Ÿ“ Fairway National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies NCT05473156Phase 1, Phase 21 site๐Ÿ“ Taipei AP Biosciences Inc. ยท Tests: AP203, AP203 Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy NCT05892354NA20 sites๐Ÿ“ Fuzhou๐Ÿ“ Fuzhou๐Ÿ“ Guangzhou First Affiliated Hospital of Guangxi Medical University ยท Tests: Enteral immunonutrition, Standard enteral nutrition Radiotherapy Alone Versus Concurrent Chemo-radiotherapy for Nasopharyngeal Carcincoma Patients With Undectable EBV DNA After One Cylce Neoadjuvant Chemotherpy NCT05674305Phase 31 site๐Ÿ“ Shanghai Fudan University ยท Tests: Radiotherapy, Cisplatin Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors NCT04777994Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ New Haven๐Ÿ“ Baltimore Calico Life Sciences LLC ยท Tests: ABBV-CLS-484, Vascular Endothelial Growth Factor Receptor (VEGFR) Tyrosine Kinase Inhibitor (TKI), Programmed Cell Deatโ€ฆ Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC (KEYSTONE-002) NCT04807673Phase 31 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Pembrolizumab, Paclitaxel, Cisplatin, neoadjuvant chemoradiotherapy GAPP Induction and Concurrent Chemoradiotherapy Followed by Toripalimab Maintenance for Nasopharyngeal Carcinoma. NCT06851247Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Toripalimab, Anlotinib, Gemcitabine, Cisplatin, radiation A Study of Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell Carcinoma NCT06354530Phase 2, Phase 31 site๐Ÿ“ Chongqing Army Medical Center of PLA ยท Tests: anlotinib, Thoracic radiotherapy Pembrolizumab and Induction Chemotherapy in Locally Advanced HNSCC NCT05272696Phase 21 site๐Ÿ“ Guangzhou Guangdong Provincial People's Hospital ยท Tests: Nab-paclitaxel, cisplatin and Pembrolizumab combination, surgery, Adjuvant Chemoradiotherapy, Radical concurrent chemorโ€ฆ Becotatug Vedotin Combined With a PD-1 Inhibitor in the Treatment of Locally Advanced Recurrent Nasopharyngeal Carcinoma. NCT07781358Phase 21 site๐Ÿ“ Shanghai Hongmeng Yu ยท Tests: Becotatug Vedotin, PD-1 / PD-L1 monoclonal antibody Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC NCT06601309Phase 21 site๐Ÿ“ Fuzhou Fujian Medical University Union Hospital ยท Tests: Serplulimab, Paclitaxel+Cisplatin (Neoadjuvant Chemotherapy), Paclitaxel+Cisplatin(Concurrent Chemoradiotherapy), Radioโ€ฆ A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC NCT07385001Phase 1, Phase 21 site๐Ÿ“ Xi'an Tang-Du Hospital ยท Tests: AK112, AK112, AK112 + Neoadjuvant chemotherapy Neoadjuvant Chemotherapy Versus Neoadjuvant Chemoradiotherapy for Resectable Locally Advanced Esophageal Cancer (HCHTOG1903) NCT04138212Phase 31 site๐Ÿ“ Zhengzhou Henan Cancer Hospital ยท Tests: Paclitaxel, Cisplatin, neoadjuvant chemoradiation therapy Perioperative Tislelizumab Plus Chemotherapy for Resectable Thoracic Oesophageal Squamous Cell Carcinoma NCT06056336Phase 21 site๐Ÿ“ Shanghai Guo Xufeng ยท Tests: Tislelizumab A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma NCT06256588Phase 3277 sites๐Ÿ“ Jonesboro๐Ÿ“ Los Angeles๐Ÿ“ Solvang GlaxoSmithKline ยท Tests: Dostarlimab, Placebo A Clinical Study on the Efficacy and Safety of Paclitaxel Polymeric Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma NCT06356688Phase 21 site๐Ÿ“ Nanjing Sun Jing ยท Tests: Paclitaxel Polymeric Micelles for Injection and Cisplatin combined with Cadonilimab Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site๐Ÿ“ Rotterdam Erasmus Medical Center ยท Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS) NCT06709417Phase 21 site๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: Sintilimab, Chemotherapy, radiotherapy Carbon Ion Re-Radiotherapy in Patients With Recurrent or Progressive Locally Advanced Head-and-Neck Cancer NCT04185974NA2 sites๐Ÿ“ Heidelberg๐Ÿ“ Marburg University Hospital Heidelberg ยท Tests: C12 re-irradiation, Photon re-irradiation Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC NCT06170710Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Anti-PD-1 monoclonal antibody, Postoperative CCRT Neoadjuvant CADI-05 in Combination With Pembrolizumab for Surgically Resectable Locally Advanced Head and Neck Squamous Cell Carcinomas NCT07455032Phase 12 sites๐Ÿ“ Philadelphia๐Ÿ“ Philadelphia Fox Chase Cancer Center ยท Tests: intradermal injection of CADI-05, Pembrolizumab PDT For Induction Therapy For Head And Neck Cancer NCT07214987Phase 22 sites๐Ÿ“ Boston๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: Toripalimab-tpzi, Cisplatin, Docetaxel The Prognostic Value of the Degree of Pathological Response of Induction Chemotherapy for NPC NCT06182657n/a1 site๐Ÿ“ Nanchang Jiangxi Provincial Cancer Hospital A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types NCT07503808Phase 115 sites๐Ÿ“ Denver๐Ÿ“ Sarasota๐Ÿ“ Detroit IDEAYA Biosciences ยท Tests: IDE034
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