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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Locally Advanced Head and Neck Squamous Cell Carcinoma

cDNA and Residual Disease After Chemoradiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinomas NCT07178847NA4 sites📍 Aurillac📍 Clermont-Ferrand📍 Lyon Centre Jean Perrin · Tests: blood sampling Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC NCT06510660Phase 21 site📍 Fuzhou Fujian Medical University Union Hospital · Tests: adebrelimab Neoadjuvant Adebrelimab Plus Chemotherapy for Esophageal Cancer: A Clinical Study NCT07437898Phase 21 site📍 Putian The Affiliated Hospital of Putian University · Tests: Adebrelimab, chemotherapy Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer NCT06173986Phase 1, Phase 21 site📍 Shanghai Shanghai Chest Hospital · Tests: PD-1inhibitor, nab-paclitaxel + cisplatin, Radiotherapy Nimotuzumab Combined With Immunotherapy and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma NCT07601737Phase 21 site📍 Shanghai Shanghai General Hospital, Shanghai Jiao Tong University Sc… · Tests: Nimotuzumab Injection, Tislelizumab, Albumin-Bound Paclitaxel /nab-Paclitaxel, Cisplatin (Or Carboplatin), Radical surg… Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites📍 Tampa📍 Chicago📍 Fairway National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies NCT05473156Phase 1, Phase 21 site📍 Taipei AP Biosciences Inc. · Tests: AP203, AP203 Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors NCT04777994Phase 130 sites📍 Tucson📍 New Haven📍 Baltimore Calico Life Sciences LLC · Tests: ABBV-CLS-484, Vascular Endothelial Growth Factor Receptor (VEGFR) Tyrosine Kinase Inhibitor (TKI), Programmed Cell Deat… Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC (KEYSTONE-002) NCT04807673Phase 31 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: Pembrolizumab, Paclitaxel, Cisplatin, neoadjuvant chemoradiotherapy A Study of Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell Carcinoma NCT06354530Phase 2, Phase 31 site📍 Chongqing Army Medical Center of PLA · Tests: anlotinib, Thoracic radiotherapy Pembrolizumab and Induction Chemotherapy in Locally Advanced HNSCC NCT05272696Phase 21 site📍 Guangzhou Guangdong Provincial People's Hospital · Tests: Nab-paclitaxel, cisplatin and Pembrolizumab combination, surgery, Adjuvant Chemoradiotherapy, Radical concurrent chemor… Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC NCT06601309Phase 21 site📍 Fuzhou Fujian Medical University Union Hospital · Tests: Serplulimab, Paclitaxel+Cisplatin (Neoadjuvant Chemotherapy), Paclitaxel+Cisplatin(Concurrent Chemoradiotherapy), Radio… A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC NCT07385001Phase 1, Phase 21 site📍 Xi'an Tang-Du Hospital · Tests: AK112, AK112, AK112 + Neoadjuvant chemotherapy Induction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal Cancer NCT06421376Phase 23 sites📍 Anyang📍 Xinxiang📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Cardonilizumab, Chemoradiotherapy ±immunotherapy, Radical surgery Neoadjuvant Chemotherapy Versus Neoadjuvant Chemoradiotherapy for Resectable Locally Advanced Esophageal Cancer (HCHTOG1903) NCT04138212Phase 31 site📍 Zhengzhou Henan Cancer Hospital · Tests: Paclitaxel, Cisplatin, neoadjuvant chemoradiation therapy Perioperative Tislelizumab Plus Chemotherapy for Resectable Thoracic Oesophageal Squamous Cell Carcinoma NCT06056336Phase 21 site📍 Shanghai Guo Xufeng · Tests: Tislelizumab A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma NCT06256588Phase 3277 sites📍 Jonesboro📍 Los Angeles📍 Solvang GlaxoSmithKline · Tests: Dostarlimab, Placebo A Clinical Study on the Efficacy and Safety of Paclitaxel Polymeric Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma NCT06356688Phase 21 site📍 Nanjing Sun Jing · Tests: Paclitaxel Polymeric Micelles for Injection and Cisplatin combined with Cadonilimab Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site📍 Rotterdam Erasmus Medical Center · Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS) NCT06709417Phase 21 site📍 Shanghai Shanghai Chest Hospital · Tests: Sintilimab, Chemotherapy, radiotherapy Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC NCT06170710Phase 21 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Anti-PD-1 monoclonal antibody, Postoperative CCRT Neoadjuvant CADI-05 in Combination With Pembrolizumab for Surgically Resectable Locally Advanced Head and Neck Squamous Cell Carcinomas NCT07455032Phase 12 sites📍 Philadelphia📍 Philadelphia Fox Chase Cancer Center · Tests: intradermal injection of CADI-05, Pembrolizumab PDT For Induction Therapy For Head And Neck Cancer NCT07214987Phase 22 sites📍 Boston📍 Boston Massachusetts General Hospital · Tests: Toripalimab-tpzi, Cisplatin, Docetaxel A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types NCT07503808Phase 115 sites📍 Denver📍 Sarasota📍 Detroit IDEAYA Biosciences · Tests: IDE034 Radiotherapy Target Volume Delineation in Locally Advanced Esophageal Cancer in the Immunotherapy Era NCT07858630n/a1 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: GTV-CTV Longitudinal Margin, Regional Lymph Node Irradiation Strategy Neoadjuvant Immunochemotherapy for LAOSCC NCT06258811Phase 31 site📍 Shanghai Lai-ping Zhong · Tests: albumin paclitaxel, cispatin, tislelizumab Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites📍 Tucson📍 Tucson📍 Irvine National Cancer Institute (NCI) · Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography Adebrelimab Combined With Neoadjuvant Chemotherapy in Borderline Resectable Locally Advanced Esophageal Squamous Cell Carcinoma NCT07638436Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Adebrelimab Injection The Efficacy and Safety of De-escalated Postoperative Radiotherapy in Locally Advanced HNSCC With pCR/MPR NCT05854823NA1 site📍 Zhuhai Fifth Affiliated Hospital, Sun Yat-Sen University · Tests: dose-reduced radiotherapy Window of Opportunity in Preserving Laryngeal Function Trial NCT07423078Phase 21 site📍 Pittsburgh Matthew Spector · Tests: Toripalimab, Carboplatin, Cisplatin, Paclitaxel, Radiation Therapy
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